Báo cáo y học: " Construction and analysis of a modular model of caspase activation in apoptosis" pot

... cleavage by caspase- 8, Bid translocates to the outer mitochondrial Figure 1 Extrinsic and intrinsic pathways to c aspase-3 activation. Overview of pathways to caspase- 3 activation. Each separate ... through a cascade activation of effector caspases (e.g., caspase- 3) by initiator caspases (e.g., caspase- 8 and -9) and the amplification of death signals implemented by...

Ngày tải lên: 13/08/2014, 16:21

... Packard CJ, Shepherd J, Lindsay GM, Gaw A, Taskinen MR: Thyroid replacement therapy and its influence on postheparin plasma lipases and apolipoprotein-B metabolism in hypothyroidism. J Clin ... from a group because of a lack of steady state in the data (in- and efflux balance), individual subjects are mentioned. - 17 - The calibrated model produced an analysis...

Ngày tải lên: 10/08/2014, 09:22

... ser- ine-type endopeptidase activity, and the other four - a disintegrin and metallopeptidase domain (ADAM) 1, 3, 5, and 26 - have the metalloendopeptidase activity. Pro- tein domain analysis ... Leakey M, Paabo S, Satta Y, Takahata N, Varki A: Inactivation of CMP-N-acetylneuraminic acid hydroxylase occurred prior to brain expansion during human evolution. Proc Natl Acad Sci USA...

Ngày tải lên: 09/08/2014, 20:21

... GTGAGTTACTAAC.CAG GTGAGTTACTAAC.CAG GTGAGTTACTAAC.CAG GTGAGTTACTAAC.CAG .TAG .GTGAGTTACTAAC.CAG .TAG GTGAGTTACTAAC.CAG 11.6% 1.5% 0.8% 5.5% 10.5% Mekouar et al. Genome Biology 2010, ... 0 Phase 1 Phase 2 3n 3n+1 3n+2 GTGAGTTACTAAC.CAG GTGAGTTACTAAC.CAG GTGAGTTACTAAC.CAG 3n 3n+1 3n+2 .GTGAGTTACTAAC.CAG .GTGAGTTACTAAC.CAG .GTGAGTTACTAAC.CAG 3n 3n+1 3n+2 G...

Ngày tải lên: 09/08/2014, 20:22

... regions, particularly North America and A ustralia. Ireland also displays a maximal or near maxima l frequency of alleles that cause or pre- dispose to a number of important diseases, including cystic ... enrichment analysis was carrie d out u sing the GOrilla ap plication [49]. The list of paralogs used in this analysis, and their associated age, were obtained from Vilel...

Ngày tải lên: 09/08/2014, 22:23

... status was sought. Statistical Analysis Statistical data analysis was carried out by means of SPSS (Version 15.0, SPSS Inc., Chicago, IL, USA). Con- tinuous data was summarized as mean ± standard deviation; ... et al.: Early and mid term mortality after coronary artery bypass grafting in women depends on the surgical protocol: retrospective analysis of 3441 on- and off-pump co...

Ngày tải lên: 10/08/2014, 09:22

... principles of Freudian metapsychology and empirical findings in neuropsychiatry Robin L Carhart-Harris* 1 , Helen S Mayberg 2 , Andrea L Malizia 1 and David Nutt 1 Address: 1 Psychopharmacology ... key terms of Freudian metapsychology Libido 'Libido means in psycho -analysis in the first instance the force (thought of as quantitatively variable and Annals of Ge...

Ngày tải lên: 08/08/2014, 23:20

... 1478-6362) Abstract Accelerated atherosclerotic vascular disease (ASVD) is a major cause of death in systemic lupus erythematosus (SLE). Although many authorities are calling for aggressive assessment and management of ... disease develops in 6–9% of SLE patients and accounts for up to 36.4% of deaths in SLE. High rates of atherosclerotic vas- cular disease (ASVD) are pa...

Ngày tải lên: 09/08/2014, 01:22

... cited. Abstract Systemic lupus erythematosus and its murine equivalent, modelled in the New Zealand Black and New Zealand White (NZB × NZW)F 1 hybrid strain, are polygenic inflammatory diseases, ... were sequenced using an ABI PRISM Big Dye terminator ready reaction kit (Applied Biosystems, Warrington, UK) and were analysed on a 3700 DNA Analyser (Applied Biosys- tems). Nucleotide...

Ngày tải lên: 09/08/2014, 06:22

... one-way analysis of variance (top left). Capital letters denote significant differences between levels (passage, collagen I coating, aggrecan coating and no coating), using a two-way analysis of ... one-way anal- ysis of variance (top left). Capital letters denote significant differences between levels (passage, collagen I coating, aggrecan coating and no coat- ing), using a...

Ngày tải lên: 09/08/2014, 10:21