Báo cáo y học: " Mitochondrial concept of leukemogenesis: ke

Báo cáo y học: " Mitochondrial concept of leukemogenesis: key role of oxygen-peroxide effects" pps

... diagram of mitochondrial (oxygen-peroxide) concept of leukemogenesisFigure 1 Structure functional block diagram of mitochondrial (oxygen-peroxide) concept of leukemogenesis. IL – induc- ers of leukemogenesis; ... Modelling Open Access Review Mitochondrial concept of leukemogenesis: key role of oxygen-peroxide effects Boris N Lyu, Sanzhar B Ismailov*, Bolat I...

Ngày tải lên : 13/08/2014, 16:21

11
124
0

Báo cáo y học: "Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis" ppt

... rheumatoid synovial tissue has been recently demonstrated. We have therefore decided to study the synovial expression of survivin, a key member of the apoptosis inhibitor family. The levels of survivin ... The study was approved by the Ethics Committee of Sahlgren- ska University Hospital. Analyses of survivin and antibodies to survivin Synovial fluid samples were obtained by arth...

Ngày tải lên : 09/08/2014, 06:22

10
505
0

Báo cáo y học: " (R)-albuterol decreases immune responses: role of activated T cells" docx

... and airway hyperresponsiveness. Activated T cells secrete cytokines that are pivotal in the pathogenesis of atopic asthma [5-7]. Further studies have elucidated the key role played by T cell ... anti- inflammatory effects displayed by albuterol isomers that may occur via T cells. Allergen-induced pulmonary inflammation is a T cell dependent process mediated by key inflammatory cytokin...

Ngày tải lên : 12/08/2014, 15:21

9
257
0

Báo cáo y học: " Th2 cytokines and asthma The role of interleukin-5 in allergic eosinophilic disease" doc

... phorbol myristate acetate, zymosan, and formyl-methionyl-leucyl-phenylalanine [25, 60–65], with a respiratory burst, activation of phospholi- pases, production of eicosanoids, and secretion of pre- formed ... hyperreactivity was abated by blocking the activity of interleukin-1, and interleukin-1β mRNA and protein levels are increased by interleukin-5. Interleukin-5 may contribute to a...

Ngày tải lên : 12/08/2014, 18:20

9
313
0

Báo cáo y học: " Bench-to-bedside review: The role of the alveolar epithelium in the resolution of pulmonary edema in acute lung injury" pps

... evidence that synthesis and open probability of ENaC increase during ALI [21]. Finally, hyperplasia of the alveolar epithelium may contribute to increased AFC in ALI [47]. Many of the factors ... have demonstrated a lack of effect of endotoxin on the integrity of the epithelial barrier [42]. The conflicting findings of preserved versus impaired AFC in ALI may be partly explained...

Ngày tải lên : 12/08/2014, 20:20

9
430
0

Báo cáo y học: "Bench-to-bedside review: The role of β-lactamases in antibiotic-resistant Gram-negative infections" potx

... generally stable to hydrolysis by all other β-lactamases that have serine at the active site of the enzyme [11]. Early reports of this group of chromosomal enzymes were from single isolates of ... these new members of the OXA family have carbapenem-hydrolyzing activity. Because hydrolysis rates may be slow compared with other carba- penemases, full carbapenem resistance may re...

Ngày tải lên : 13/08/2014, 20:21

8
506
0

Báo cáo y học: " Updating the evidence for the role of corticosteroids in severe sepsis and septic shock: a Bayesian meta-analytic perspective" pot

... estimates of current therapeutic efficacy would suggest analysis excluding the former study, the result of which was to reduce hetero- geneityofthemortalityeffectby40%andtoreveala probability of corticosteroid ... American Association of Critical-Care Nurses; American College of Chest Physicians; American College of Emergency Physicians; Canadian Critical Care Society; European So...

Ngày tải lên : 13/08/2014, 21:21

15
536
0

Báo cáo y học: "The concept of “compartment allergy": prilocaine injected into different skin layers" pdf

... Contact Allergy Group (DKG) series as well as key substances of plaster ingredients (acrylates, benzoylperoxide, substi- tuted glycidylethers, diaminodiphenylmethan) and methylhydroxybenzoate were ... are most often caused by ester compounds of LA putatively because of its metabolite paraaminobenzoeacid (PABA) as the relevant antigenic structure [3]. Delayed-type hypers ensitivity aga...

Ngày tải lên : 08/08/2014, 21:20

4
376
0

Báo cáo y học: " Mitochondrial targeting of human NADH dehydrogenase (ubiquinone) flavoprotein 2 (NDUFV2) and its association with early-onset hypertrophic cardiomyopathy and encephalopathy" ppt

... the mitochondrial targeting of this protein (data not shown). Establishing the human disease mechanism of the early- onset hypertrophic cardiomyopathy and encephalopath The patients of early-onset ... with early-onset hypertrophic cardiomyopathy and encephalopathy. Conclusions In conclusion, the MTS of NDUFV2 is located at the N- terminus of the precursor protein and is proteoly...

Ngày tải lên : 10/08/2014, 05:21

17
434
0

Báo cáo y học: "Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathoge"nesis of the disease potx

... phosphorylation, decreased mitochondrial membrane potential, increased production of reactive oxygen species (ROS), activation of mitochondrial permeability transition (MPT), mitophagy of dysfunctional ... collapse of mitochondrial membrane potential and the elimination of dysfunctional mitochondria by mitophagy. Our results support this hypothesis, showing the presence of...

Ngày tải lên : 12/08/2014, 11:22

11
288
0