Báo cáo y học: " Extracting key information from historical data to quantify the transmission dynamics of smallpox" doc

... findings, empha- sizing the importance of systematically analyzing histori- cal datasets. Review Extracting key information from historical data Although historical data have frequently been revisited using ... sufficiently quantifying the detailed intrinsic mechanisms by using observed data [6,19,20]. Because of the global eradica- tion, we have had to maximize...

Ngày tải lên: 13/08/2014, 16:21

... tame their stock. They argued that feeding roasted salted maize grains from the palm to animals that are new to the flock aided the animals’ recognition of the farmer to the extent that the animal ... of other key informan ts who were considered to ha ve good knowledg e of specific issues of interest to the study and were prepared to share it [25]. Key...

Ngày tải lên: 10/08/2014, 09:21

... the safety of a single drug but rather to the evaluation of the wide variety of medications that are used to treat a specific disease during pregnancy. Second, the objectives of the study are not ... summary, the prenatal effects of high dose hydroxy- chloroquine used for the treatment of RA have not been studied adequately. However, the available data on th...

Ngày tải lên: 09/08/2014, 08:22

... gene therapy protocols because of the ease of their production and the broad cell tropism, par- ticularly within the cardiovascular system which makes them widely used in myocardial gene therapy. ... are poorly understood, the fundamental hypoth- esis is that, according to the nat ure of signaling stimu- lus, the cardiomyocytes (CMs) can either survive, leading to benefi...

Ngày tải lên: 10/08/2014, 09:21

... bifurcated hydrogen bonds with the thymine or adenine bases. The central N5(D) atom of the drug is hydrogen-bonded to the two O2 atoms of the thymine bases of the central AT steps. Nitrogen atoms N3(D) ... electron density, whereas the rest of the drug molecule fits these maps nicely (Fig. 2B). Also the temperature factors of these two atoms are much higher than t...

Ngày tải lên: 24/03/2014, 04:21

... type III HAE) with the defec ts yet to be identified. The pathophysiology of HAE-C1INH types I and II appears to relate to bradykinin resulting in angioedema. HAE may present under one year of ... Prophylaxis Short Term Prophylaxis HAE patients are encouraged to CARRY TWO DOSES of any of the angioedema event THERAPIES (AERx’s) to have immediately available for ang...

Ngày tải lên: 08/08/2014, 21:20

... ampullary and pancreatic tumors. Hepatogastroenterology 2000, 47:540-544. 11. Nakamura E, Shimitzu M, Itoh T: Secondary tumors of the pancreas: clinicopathological study of 103 autopsy cases of Japanese ... pan- createctomy and splenectomy. From a review of surgical outcomes of previously reported cases including our patient and less than 5% of surgical mortality rate in pan-...

Ngày tải lên: 09/08/2014, 03:21

... against cytotoxic H 2 O 2 cytotoxicity to a similar degree, an effect that could be ascribed either to the direct enzymatic detoxification of H 2 O 2 through the GSH-peroxidase activity of GSTA4-4 ... articular chondro- cytes and as the main precursor for the synthesis of ECM gly- cosaminoglycans in cartilage [35,36]. The inhibition of proteoglycan synthesis in OA chondr...

Ngày tải lên: 09/08/2014, 13:21

... all research topics related to rheumatology. In 2003, the name of the journal was changed to Arthritis Research & Therapy to denote the journal’s aim of incorporating translational aspects of rheumatology ... rheumatology in the past decade. We hope it will not only give the basic investigator a comprehensive overview of the state of knowledge of rheumatology...

Ngày tải lên: 09/08/2014, 13:22

... results in the pro- duction of toxic halides and the hydroxyl radical [20]. MPO activity was assessed in leukocytes (KRG, 10 7 cells/ml) and measured spectrophotometrically as the oxidation of 4-aminoantipyrine ... response to NADPH oxidase-triggering peptides is related to the severity of RGBS. The mechanistic a spects of this asso- ciation should be the subject of...

Ngày tải lên: 11/08/2014, 03:20