Báo cáo y học: "A continuum mathematical model of endothelial layer maintenance and senescence" ppsx

... Access Research A continuum mathematical model of endothelial layer maintenance and senescence Ying Wang, Baltazar D Aguda and Avner Friedman* Address: Mathematical Biosciences Institute, and Department of ... model monitored the changes of the EC monolayer over a period of 60 years, with a discrete time step of 1 year. Dead ECs could be replaced either by divi...

Ngày tải lên: 13/08/2014, 16:21

... discrete model of the cell cycle and a continuous macroscopic model of tumor growth and invasion. The basis of the model is that the sensitivity to irradiation depends on cell cycle phase and that ... purposes) Theoretical Biology and Medical Modelling Open Access Research A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies B...

Ngày tải lên: 13/08/2014, 23:20

... strongly non- monotonic behavior of parameter ψ(t) in some of our modeling scenarios can possibly be explained by applying the concept of dynamic speciation to the formation of a toxin- antibody complex ... a system of cells), but also provides a high fidelity estimation of the limiting uptake rate of toxin by a cell (especially when it is limited by diffusion). More importantly...

Ngày tải lên: 13/08/2014, 16:20

... their physiology and immunology.  ese physiological diff er- ences may limit their validity in safety and toxicity tests. Disparities between humans and marmosets in the immune system will ... novel and promising non-human primate model of RA for preclinical research. With regard to its experimental handling and practicability, as well as its evolutionary distance from huma...

Ngày tải lên: 12/08/2014, 15:22

... Barbini 1 1 Department of Surgery and Bioengineering, University of Siena, Viale Bracci, 53100 Siena, Italy 2 Department of Physiopathology, Experimental Medicine and Public Health, University of Siena, Via ... a probability threshold to be compared with the predicted model probability of morbidity [28]. By using the sensitivity (SE) and specificity (SP) values, the ROC curv...

Ngày tải lên: 12/08/2014, 23:24

... and mortality assumptions [12], vaccine efficacy, duration of vaccine efficacy (varied by both an assumption of limited dura- tion of full vaccine efficacy followed by no efficacy and also by ... utility gain from prevention is the utility that would otherwise be lost due to illness. An extension of the standard utility model and analysis of prevention interventions is offer...

Ngày tải lên: 13/08/2014, 11:22

... to be 0.6, and a body surface area of 1.73 m 2 is assumed. Tumor cord geometry parameters Vessel and cord radii Tumors can vary greatly in the level of perfusion and in the regularity of their ... study, it is not nec- essary to consider the effects of hypoxia, and I only con- sider the viable part of the tumor cord. A schematic of the circulation coupled to the tumor cor...

Ngày tải lên: 13/08/2014, 16:20

... our study only documented exact values of GCS and SBP in 48% and 53% of records, respectively. Exact RR was documented in 10% and RR RTS cate- gory in 54%. One cause of this discrepancy may be that ... emergency vehi- cle with light -and- siren response for the study purpose only. This study of documentation quality was part of a cross-sectional MVA study evaluating whether pa...

Ngày tải lên: 25/10/2012, 09:56

... The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability. Crit Care 2008, 12:R129. 40. Rattanataweeboon P, Vilaichone W, Vannasaeng S: Stress hyperglycemia in ... 4 of 8 underlying physiology, there is a combination of physio- logical factors predisposing a patient for hyperglycaemia in acute illness, during which hyperglycaemic mecha- nisms i...

Ngày tải lên: 25/10/2012, 10:02

... University of Maryland, Baltimore, Maryland, USA, 3 Departments of Psychiatry and Pediatrics, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA, 4 Department of Social Pharmacy, Pharmacoepidemiology ... Glaeske 5 and Satish C Valluri 1 Address: 1 Pharmaceutical Health Services Research, School of Pharmacy, University of Maryland, Baltimore, Maryland, USA, 2 Dep...

Ngày tải lên: 25/10/2012, 10:06