Báo cáo y học: "Optimization principles of dendritic structure" docx

... Research, Department of Physiology, University College London, UK, 2 Department of Physiology, University College London, UK , 3 Max-Planck Institute of Neurobiology, Department of Systems and Computational ... integration of spatially dis- tributed inputs are characteristic of many dendrites; these principles may well therefore be applicable for many other systems. In recent...

Ngày tải lên: 13/08/2014, 16:21

... analyzed the morphology of type I DA neurons in these mutant flies. In most cases, the mutant alleles pro- duced a phenocopy of the RNAi phenotype, validating the accuracy of the approach. Analysis ... that affect different aspects of dendrite arborization. But is there any unity of mechanism behind the functional unity of each group? The answer is likely to be yes. For instance,...

Ngày tải lên: 14/08/2014, 16:21

... cell separates the Analysis of the essentiality of hubs and composite hubsFigure 2 Analysis of the essentiality of hubs and composite hubs. (a) Comparison of the percentages of essential genes in ... revealed by global comparisons and composite motifs Haiyuan Yu ¤ , Yu Xia ¤ , Valery Trifonov and Mark Gerstein Address: Department of Molecular Biophysics and Biochemistry, Whitn...

Ngày tải lên: 14/08/2014, 16:21

... very high pK a value of Tyr16 can only be attributed to a highly desolvated environment, contributed by hydrophobic residues from both monomers. The role that Tyr16 plays in the structure of ... highly charged and has not been the subject of detailed study. The hydrophobic and charged faces of the RIIa D/D are diametrically opposed to each other. Interestingly, phosphorylation of RI...

Ngày tải lên: 08/03/2014, 22:20

... University of Pennsylvania School of Medicine, Philadelphia, PA, USA and 3 Division of Neonatal-Perinatal Medicine, Division of Pulmonary and Vascular Biology, Room K4.224, University of Texas ... signifi- cant cause of morbidity and mortality affecting as many as 30–40% of infants born less than 30 weeks gestation [1]. While the pathophysiology of BPD includes both inflam-...

Ngày tải lên: 12/08/2014, 16:20

... ret- roviral envelope glycoproteins of at least one of them (HERV-W and possibly ERV-3) may be involved in natural syncytium induction to form the syncytiotrophoblast [61- 63]. Murine mammary tumor virus ... phylogeny Host phylogeny Retrovirology 2006, 3:67 http://www.retrovirology.com/content/3/1/67 Page 4 of 11 (page number not for citation purposes) Temin's provirus hypothesis v...

Ngày tải lên: 13/08/2014, 09:20

... Complex systems admit many descriptions (ways of looking at the system) each of which is only partially true. Each way of looking at a complex system requires its own description, its own mode of analysis ... which the principles of the thermodynamics of "closed" systems studied by physicists do not apply. Unlike closed systems (in which a state of equilibrium is est...

Ngày tải lên: 13/08/2014, 23:20

... regulation of translation of maternally inherited mRNA by cytoplasmic polyadenylation in Xenopus oocytes. Polyadenylation is required before the mRNA can be trans- lated, and regulation of this ... therefore necessary for oocyte maturation and embryonic development. Cytoplas- mic polyadenylation depends on phosphorylation of CPEB, a protein that is bound to specific cytoplasmic polyad...

Ngày tải lên: 14/08/2014, 14:21

... matrix of SLNs is composed of solid li- pids. The majority of lipids commonly used are trig- lyceride esters of hydrogenated fatty acids. Hydro- genated cottonseed oil (Lubritab™ or Sterotex™), hydrogenated ... poly- dispersity and entrapment efficiency for all the pre- pared formulae. The polydispersity index is a meas- ure of the width of the dispersion of particles. Narrow...

Ngày tải lên: 25/10/2012, 11:22

... Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR- agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity. Journal of Inflammation 2010 ... advan- tages of targeting DCs is their role as key initiators of adaptive immunity, t hereby positioned upstream of the effector cells in e.g. autoimmunity [1,8]. Furthermore...

Ngày tải lên: 11/08/2014, 06:22