Báo cáo y học: "Time variations in the transmissibility of pandemic influenza in Prussia, Germany, from 1918–19" pdf
... onwards. Distribution of the time delay from onset to death during the influenza epidemic in Prussia, Germany, from 1918–19Figure 2 Distribution of the time delay from onset to death during the influenza ... time variations in the transmissibility of pandemic influenza. The findings imply a need to detail the natural history of influenza as we...
Ngày tải lên: 13/08/2014, 16:21
... every 6 to 8 hours) or by continu- ous infusion (3 to 4 IU/kg/hour) [2]. The Bethesda assay was not immediately available in our case and the lack of another bypass agent in the setting of severe ... adjusted depending on plasma FVIII levels and bleeding symp- toms [2]. Another interesting finding in our case was the p resence of persistent melena for two weeks in the...
Ngày tải lên: 11/08/2014, 03:20
... use in acquired hemophilia in the US [2]. By directly activating FX on the surface of activated platelets at the site of injury (thereby bypassing FVIII and FIX), rFVIIa can circum- vent the ... bradycardia that developed in the setting of severe bleeding from acquired factor VIII inhibitor, but the authors did not address whether this bradycardia was associated with...
Ngày tải lên: 11/08/2014, 07:20
Báo cáo y học: " New approaches to the modulation of inflammatory processes in airway disease models" pdf
... delivered directly into the airways, can be transformed by esterase cleavage into the active metabolite (R-M1) producing high local anti-inflammatory activity. The anti-inflammatory effi- cacy of Ciclesonide ... increased the secretion of serous mucus in mouse trachea as well as reducing LPS-induced neutrophilia in rats and pigs. Kinase inhibitors In a session on the role...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: "Black Hawk Down: The evolution of resuscitation strategies in massive traumatic hemorrhage" doc
... work is one of generalizeablity, since the patient population consisted of young, otherwise healthy men suffering primarily penetrating injuries from combat trauma. Whether these findings translate ... after the institution of an early goal directed therapy protocol calling for a 1:1 ratio of plasma to RBCs within the first 6 hours of injury [10]. Sperry and colleague...
Ngày tải lên: 13/08/2014, 11:22
Báo cáo y học: "Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages" pdf
... group of ROS (direct effect) or stim- ulating the synthesis of the cellular GSH levels and therefore protecting the cells against oxidants (indirect effect) by modulating the redox signaling pathways [22,23]. ... in designing the experiments and took part in critical revision of the manuscript. FN partic- ipated in the design and coordination of the study. GF con...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: " Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNF-induced MEK/ERK signalling" ppsx
... TNF-activated NFB-DNA binding activity. The regulation of NFB-DNA binding in primary cells can therefore be explained by the non- specific effect of DMSO on NFB activation. In the present study we determined ... cate- gorized by the molecular function of their protein products into categories that included hyaluronic acid binding activity (including Agc1 and Hapln1) and...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Tandem repeats modify the structure of human genes hosted in segmental duplications" docx
... manually analyzed all these 40 modifications in order to verify the effect of the repeats on the resulting pro- teins. In the majority of cases, the reading frame of the origi- nal protein is ... retention of repeats that can significantly diversify the sequence of the encoded proteins. Fifty percent of variable ITRs modify protein sequences In agreement with...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "DNA transposons and the role of recombination in mutation accumulation in Daphnia pulex" pdf
... and the back-up individuals were dead, the line was propa- gated from beakers of animals from previous genera- tions of the lineage also maintained in the lab (at 10°C) by selecting a ra ndom individual ... Coordination infrastructure for the DGC is provided by The Center for Genomics and Bioinformatics at Indiana University, which is supported in part by the METACyt...
Ngày tải lên: 09/08/2014, 20:21