Báo cáo y học: "A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis" pot

... Access Research A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis Evgeniya A Oshchepkova-Nedosekina* and Vitalii A Likhoshvai Address: Institute of Cytology and ... was under way. The values obtained for the parameters are shown in Table 1. Methods The model to describe the reaction catalyzed by adenylo- succi...

Ngày tải lên: 13/08/2014, 16:21

... studies. Results In Figure 1, we compare the amounts of LH released in 5 minute intervals in the original model and the present model in response to continuous administration of 5 nM GnRH. In both models there ... endothelin at one hour intervals. Note that the response to Endothelin is markedly different than the response to GnRH in Panel A of Figure 14. If we chan...

Ngày tải lên: 13/08/2014, 22:22

... [26], the hybrid individual-continuum model of [11], the hydrogel model of [20], and the diffusion -reaction model [27]. For our study we bui ld on the prototype biofilm model of [16], in which the ... throughout the paper. We formulate this model in the framework of the density-dependent nonlinear diffu- sion model for biofilms which was originally introd...

Ngày tải lên: 13/08/2014, 16:20

... the model can reasonably detect the genetic control of cancer incidence curves. In practice, our model can formulate a number of meaningful hypotheses, e.g., (7)-(9). In this study, these hypothesis tests ... whether there is a difference in age-specific genetic effects between the two environments. This can be tested by formulating the following hypotheses: The critical v...

Ngày tải lên: 13/08/2014, 16:21

... corresponding to a fast-rising, fast-decaying effect of insulin on peripheral tissues. We therefore set and we define as the average time for the metabolic effect of insulin in changing glyc- emia. The ... Rome the evening before the study. At 07.00 hours on the following morning, the infu- sion catheter was inserted into an antecubital vein; the sampling catheter was intr...

Ngày tải lên: 13/08/2014, 23:20

... significantly lower inthearea8.0cmfromtheentryuptotheexitofthe projectile as compared with the size of the temporary cavity. Discussion This model for examining potential wound contamina- tion ... been involved in drafting the manuscript. NCG was involved in revising the manuscript. All authors read and approved the final manuscript. Competing interests The authors dec...

Ngày tải lên: 11/08/2014, 20:21

... mixed inhibition [37]. Ornithine there- fore binds to the active site of CyrA at a binding site distinct from the hydroxylamine-binding site. This binding affects the rate of reaction by factor ... spectro- photometrically by following the formation of orni- thine upon incubation with l-arginine and glycine. Although this indicated the utilization of l-arginine as a substrate by C...

Ngày tải lên: 06/03/2014, 22:21

... selec- tion and, therefore, bias in the dataset. Further, allowance had to be made for the variability in admission criteria for the various hospitals across Spain. Finally, since day care attendance ... hospitalised infants within the Munich study. Further, only six of the hospitalised infants had a confirmed diagnosis of RSV, as testing is not routine in Germany. Taking...

Ngày tải lên: 12/08/2014, 14:20

... 14 E I i I j dA I i I j dA jji n i = ∫ − () ∫ + () ⎧ ⎨ ⎪ ⎪ ⎩ ⎪ ⎪ ⎫ ⎬ ⎪ ⎪ ⎭ ⎪ ⎪ ∫∫ =≠= ∑ Ω Ω   2 2 11, nn ∑ , (2) where Ω denotes the image domain. Minimizing the energy function (2) is equivalent to simultaneously minimizing the diffe rence betwe en any pair of binary images in the training database. What ... technique yields n level sets functions Y= {Y 1 , Y 2 , Y n } co...

Ngày tải lên: 13/08/2014, 16:20

... time points: 4, 7, 15 and 24 h for cells pre- senting a biofilm phenotype and for cells in the planktonic state. For this purpose, they grew the two groups of cells in the same reactor in order ... clustering, performed the model and the statistical analysis, and drafted the manuscript. SRR participated in the design of the study and helped to draft the manus...

Ngày tải lên: 13/08/2014, 16:20