Báo cáo y học: "Even without our biases, the outlook for prognostication is grim" docx

... appropriate recommendations for our patients. There is no safety in numbers. Commentary Even without our biases, the outlook for prognostication is grim James Downar 1,2,3,4 1 University Health Network, ... II score? The evidence suggests that physician prognostication consis- tently and significantly outperforms prediction models such as the APACHE II score [2], a...

Ngày tải lên: 13/08/2014, 16:21

... all of these genetic polymorphisms comprised a haplotype. We therefore checked the genotypic data reported by other investigators and estimated the carry- ing rate of each haplotype in the disease ... of IL-18 is a characteristic feature in both AOSD and systemic JIA, which is the reason why many investigators may consider these two diseases to be the same entity. The human IL...

Ngày tải lên: 09/08/2014, 07:20

... analysis. Microcirculatory analysis For quantitative off-line analysis, a computer-assisted image analysis system was used (CapImage v7.4; Zeintl, Heidelberg, Germany). The functional capillary ... together, these findings testify that orally administered PC is able to interfere with inflammation, but the critical time for PC involvement is during the onset of CIA. The exact p...

Ngày tải lên: 09/08/2014, 14:20

... a very low percentage of cells with JAK2V617F, it may take many years to show a clear MPN symptom, and some may never reach the stage before they die of other diseases. It is also likely that JAK2V617F-bearing ... met the criteria for diagnosis of MPNs, but many of them had other conditions including cardiovascular diseases, which may be the result of underlying hematological disord...

Ngày tải lên: 10/08/2014, 21:23

... mitochondrial therapy are not clearly defined. Efforts in this direction have already been made [15] and may be among the keys to future sepsis therapy. Competing interests The authors declare that they ... Clearly, these haemodynamic effects are typical for endotoxin- induced sepsis but not for hyperdynamic sepsis, as is en- countered in patients receiving adequate haemodynamic sup...

Ngày tải lên: 13/08/2014, 11:22

... Vahlbruch J, Hoy L, Haller H, Fliser D, Kielstein JT: The Hannover Dialysis Outcome Study: comparison of standard versus intensified extended dialysis for patients with acute kidney injury in the intensive ... studies where dialysis dose is normalized to body weight, other difficulties may arise as well. What should be considered as ‘body weight’: dry weight, weight before admission,...

Ngày tải lên: 13/08/2014, 16:20

... Agency of Canada (PHAC). The funding body had no role in study design, in the collection, analysis, and interpretation of the data, in the writing of the manuscript, or in the decision to submit the ... body fat) have pro- duced consistently high values for steps/day: 15,000- 16,000 steps/day for boys and 12,000-13,000 steps/day for girls [23,54], but these findings may be...

Ngày tải lên: 14/08/2014, 08:20

... CG: Tracheotomy: why, when, and how? Respir Care 2010, 55:1056-1068. 6. Trouillet JL, Combes A, Luyt CE, Nieszkowska A, Chastre J: Early tracheotomy: the end of the controversy. Reanimation ... Guillain-Barré syndrome; MV, mechanical ventilation; NIMV, non-invasive mechanical ventilation. Competing interests The authors declare that they have no competing interests. Published: 20 May...

Ngày tải lên: 14/08/2014, 08:21

... analyses to explore other phenotype-genotype associations that were not initially hypothesized, specifically the possibility that a particular length may be associated with disease or a disease ... ov er half of the samples were run twice. The raw sizing data were visually analyzed for peak quality followed by analysis and bin- ning using the GeneMapper software (Applied Biosys- tem...

Ngày tải lên: 12/08/2014, 15:22

... deterioration. The latter study does have several weaknesses, which the authors themselves point out. The study is retrospective and there is no ability within the data trawling to identify causes of delay. ... availability of an intensivist outside working hours and mortality was observed. This may in part be explained by the excellent provision of ICU-trained doctors in The...

Ngày tải lên: 13/08/2014, 08:20