Báo cáo y học: " The international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and patient outcomes" ppsx

Báo cáo y học: "The International Sepsis Forum’s controversies in sepsis: my initial vasopressor agent in septic shock is norepinephrine rather than dopamine" pot

... weakβ-agonist chronotropic effect of norepinephrine is counterbalanced by an increased venous capacitanceCommentaryThe International Sepsis Forum’s controversies in sepsis: my initial vasopressor agent ... to consider using norepinephrine first. Norepinephrine produces less tachycardia Norepinephrine- induced increase in blood pressure occurswith little change in the heart rate. This is because the ... contrasting effects of dopamine and norepinephrine on systemic and splanchnic oxygen utilization in hyperdynamic sepsis. JAMA 1994, 272:1354-1357.12. Martin C, Eon B, Saux P, Aknin P, Gouin F:...

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Báo cáo y học: "The International Sepsis Forum’s controversies in sepsis: my initial vasopressor agent in septic shock is dopamine rather than norepinephrine" pptx

... norepinephrine, butthese are exceptional cases.CommentaryThe International Sepsis Forum’s controversies in sepsis: my initial vasopressor agent in septic shock is dopamine rather than norepinephrineJean-Louis ... The International Sepsis Forum’s controversies in sepsis: my initial vasopressor agent in septic shock is norepinephrine rather than dopamine. Crit Care2003, 7:3-5.3. Bailey AR, Burchett KR: ... Moreover, thistachycardia is usually well tolerated; it is rare to see thedevelopment of myocardial ischaemia secondary to septic shock. Admittedly, in some cases, in which the heart rate is very fast,...

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Báo cáo y học: " The International Sepsis Forum’s frontiers in sepsis: high cardiac output should be maintained in severe sepsis" ppt

... this strategy should be tailored to the individual patient. Hayes andCommentary The International Sepsis Forum’s frontiers in sepsis: high cardiac output should be maintained in severe sepsis Jean-Louis ... concentrations. The concept is to assess the adequacy of the cardiac output in patientswith severe sepsis, enabling management strategies aimed at optimizing cardiac output to be tailoredto the individual ... tomathematical coupling of data. In complex cases, the relationbetween cardiac index and oxygen extraction ratio may be helpful, especially in anemia [15,16]. Finally, blood lactatelevels may...

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Báo cáo y học: "The International Sepsis Forum’s frontiers in sepsis: high cardiac output should not be maintained in severe sepsis" pptx

... by aCommentaryThe International Sepsis Forum’s frontiers in sepsis: high cardiac output should not be maintained in severe sepsis Vinay K Sharma1and R Phillip Dellinger21Attending Physician, ... subsequent increases in DO2do not result in any further increase in VO2(Fig. 1). Attempts to increasethe DO2beyond this point are more likely to be harmfulbecause the methods used (e.g. inotropes) ... (such as increased oxygen demand in tissues,tachyarrhythmias, worsening distribution of blood flow in tissues, and myocardial ischemia).What is the rationale for maintaining high cardiac output? The...

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Báo cáo y học: " The international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and patient outcomes" ppsx

... [18].Demographics of adult patients with severe sepsis from the PROGRESS registry are displayed in Table 1. Approximately7% of the patients in the database received DrotAA (882 of 12,492). There were ... pre-sented in Table 6. Germany was the highest enrolling country of the PROGRESS Registry and the US had twice the number of patients treated with DrotAA as the next highest country(Canada). Enrollment ... for citation purposes)Vol 13 No 3Research The international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and patient outcomesGreg Martin1, Frank M Brunkhorst2,...

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Báo cáo y học: " The reticulons: a family of proteins with diverse function" pptx

... 160:224-235.36. Iwahashi J, Kawasaki I, Kohara Y, Gengyo-Ando K, Mitani S, Ohshima Y, Hamada N, Hara K, Kashiwagi T, Toyoda T: Caenorhabditiselegans reticulon interacts with RME-1 during embryogene-sis. ... factor betaPIX. J CellBiochem 2006, 99:1203-1215.41. Wakana Y, Koyama S, Nakajima K, Hatsuzawa K, Nagahama M, TaniK, Hauri HP, Melancon P, Tagaya M: Reticulon 3 is involved inmembrane trafficking ... protein remains a possible candidate drug target for the disease.Lastly, RTN4 may have a role in multiple sclerosis andhereditary spastic paraplegia. Autoantibodies against the isoform A- specific...

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