Báo cáo y học: " When once is not enough – further evidence of procalcitonin-guided antibiotic stewardship" pot

... action by the study physicians or was overruled by the physicians in charge. Second, the precise microbiologic etiology of the causative organisms and the documented relapse rate, secondary infections ... still-high costs of this test and unforeseen adverse consequences if used indiscriminately. Despite these limitations, the study by Hochreiter and colleagues presents another piece of...

Ngày tải lên: 13/08/2014, 16:21

... responsibility for the integrity of the data and the accuracy of the data analysis. Both authors contributed equally to the study. Study concept and design: ET, JB, FJA, IGC, JIGH. Data acquisition: ... decrease SSIs. In contrast to the findings of Belda et al. [2], clinical trials by Pryor et al. [4] and, more recently, by Meyhoff et al. [5], found no difference in SSI risk when 80%...

Ngày tải lên: 10/08/2014, 09:23

... the characteris- tics of the individual (e.g. genotype, coping strategy, expectation and previous experiences). Given the com- plexity, it is not surprising that a variety of control inter- ventions ... deconditioning/extinction of, for example, knee osteoarthritis pain [91,92]. In such a scenario, the construction of a placebo control is virtually impossible, as any kind of se...

Ngày tải lên: 13/08/2014, 15:21

... essentially the severity of the underlying disease. © 2010 BioMed Central Ltd Atrial  brillation is not just an artefact in the ICU Philippe Seguin* and Yoann Launey See related research by Meierhenrich ... mortality. Interestingly, they reported a signifi - cant and continuous increase in C-reactive protein levels the days before the occurrence of AF, corroborating previous fi ndin...

Ngày tải lên: 13/08/2014, 21:20

... HIV is the most prevalent is at risk for many dis- eases, not only HIV. We add to the jeopardy of this child by some of the interventions we provide as part of PMTCT programmes. This jeopardy is ... programmes in many places, and both continu- ity of care and follow up is very often poor. Quality of counselling, particularly as it relates to infant feeding, is of poor...

Ngày tải lên: 20/06/2014, 08:20

... the hypothesis that uric acid (UA), regardless of crystal deposition, may play a direct pathogenic role in multiple diseases, including renal disease [4,5]. UA is a ubiquitous by-product of purine ... maximum weekly levels of 21 and 14 units for males and females, respectively; none of them was hyperuricaemic. This is why we have not included alcohol consumption in the univariab...

Ngày tải lên: 09/08/2014, 14:22

... and tumor necrosis factor-α (TNF-α). Functionally active NF- κB exists mainly as a heterodimer consisting of subunits of the Rel family, and this heterodimer is normally sequestered in the cytosol as ... Assay or by biochemical assay. Expression of IκB, p50, p65, inducible nitric oxide synthetase (iNOS), cyclooxygenase-2 (COX- 2) as well as phosphorylation of MAP kinase family was d...

Ngày tải lên: 11/08/2014, 08:22

... n theairwayofmicebyusingthePASstain.ThePAS stain is mainly used for stai ning str uctures containing a high pro portion of carbohydrate macromolecules (glyco- gen, glycoprotein, and proteoglycans), typically ... 40 objective lens. Visualization of th e nuclei was by 4’,6-dia- midine-2’-phenylindole, dihydrochloride (DAPI) staining. Statistical analysis Analyses were performed using SPSS...

Ngày tải lên: 12/08/2014, 13:22

... reversible phenotype switching, which confers broad functional capacity [4,5]. At one extreme airway myocytes exist in an immature phenotype that is characterised by a high ten- dency for proliferation, ... secretion of ECM proteins, and synthesis of inflammatory mediators in response to a number of environmental cues [4-7]. In con- trast, myocytes of a mature phenotype serve a prim...

Ngày tải lên: 12/08/2014, 16:20

... ventilation primarily due t o ALI, pneumonia, influenza, aspiration, exacerba- tion of chronic obstructive airway disease, or other acute lung disorder. Statistical analysis On the basis of previous ... significantly reduced histological and other evidence of pulmonary microvascular thrombosis [13,35]. Animal models of sepsis and ALI have also demonstrated reduced micro- vascular th...

Ngày tải lên: 13/08/2014, 21:21