Báo cáo y học: "Incretins in the ICU: is insulin on its way out" pdf

... and induction of satiety [8-12]. The beauty of GLP-1 is that it does not stimulate Commentary Incretins in the ICU: is insulin on its way out? Michelle A Kovalaske and Gunjan Y Gandhi Division ... effects on insulin and glucagon in hospitalized patients. Finally, GLP-1 in and of itself may not cause hypoglycemia. When used in conjunction with insulin, however,...

Ngày tải lên: 13/08/2014, 16:21

... beginning in the medulla and extend- ing to the midbrain. This pathway links the brain with perception of external events. Pain is a very potent activa- tor of this system, and this explains the ... the brain. CRF is anxiogenic when injected intravenously, probably interacting with noradrenergic neurons in these areas, increasing activity [63]. CRF may Review Agitation in...

Ngày tải lên: 12/08/2014, 18:20

... trials of intensive insulin therapy in the ICU found that electrophysiological abnormalities suggestive of polyneuro- pathy were less common in patients receiving tight glycemic control [7]. Another ... pathological responses that may be compounded by systemic inflammation, infection, hypercortisolemia, and malnutrition [9]. In healthy volunteers and in critically ill patients, be...

Ngày tải lên: 13/08/2014, 19:20

... performed in order to investigate additional outcomes, primarily the safety of epoetin alfa for this indication.  e study design was virtually the same as the 2002 study, although the current ... fi ndings, however, are not entirely conclusive. With further analysis, the authors showed that the increase in throm botic events only aff ected patients not receiving heparin pr...

Ngày tải lên: 14/08/2014, 07:21

... for the two- subunit wild-type complex confirms the contribution of additional charge(s) located on the two further subunits of the native oxidase. In focussing on the main interaction domain on ... not address the question whether any other (aromatic) side chains in this or the neighbouring position might be able to support electron transfer to the Cu A site, thereby...

Ngày tải lên: 22/02/2014, 07:20

... This raises the possibility that any one or a combination of these properties may in uence the binding of apolipoproteins to lipoprotein particles. The capacity to fractionate lipid emulsions into ... analysis, 1000 synthetic data sets were generated, based on the best-fit continuous size distribution, each with different normally distributed noise. For each point in the distrib...

Ngày tải lên: 08/03/2014, 09:20

... 1 Classification of Chronic Rhinosinusitis Recurrent acute rhinosinusitis Chronic purulent rhinosinusitis Chronic hyperplastic rhinosinusitis Chronic rhinosinusitis with polyposis Samter’s triad 3 Allergic ... involving the paranasal sinuses (chronic hyperplastic rhinosinusitis) but without polypo- sis and those patients with diffuse sinonasal polyposis with polyps projecting into or com- p...

Ngày tải lên: 08/08/2014, 20:23

... characterized by hyperactivation of the complement classical pathway, hypoactivation of the complement alternative pathway and overactivation of the terminal pathway. Conclusions: The results obtained ... compo- nents of the alternative pathway, and C3 is the initial point for the alternative pathway and a converge point of all three complement activation pathways, starting up...

Ngày tải lên: 08/08/2014, 21:20

... are strongly related to risk of loss, especially overlying the lesion. BMLs are not the only bone feature related to pain in OA. Attrition of bone is more common in persons with knee pain and ... inflammation at the boney insertion of the collateral ligaments [5] and histological examination shows synovitis investing the ligament insertion sites [6]. In knees, similar bone l...

Ngày tải lên: 09/08/2014, 01:22

... Clinical Disease Activity Index (CDAI) [13]. Indeed, the lower the disease activity category that can be attained under therapy, the lower the progression of joint damage [12,22]. On the other ... consequence of the activation of many cell populations and, ultimately, of the upregulation of proinflammatory cyto- kines [19,20]. By whichever means they themselves become activate...

Ngày tải lên: 09/08/2014, 01:22