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Báo cáo y học: "Infra-red thermometry: the reliability of tympanic and temporal artery readings for predicting brain temperature after severe traumatic brain injur" pot

Báo cáo y học:

Báo cáo y học: "Infra-red thermometry: the reliability of tympanic and temporal artery readings for predicting brain temperature after severe traumatic brain injur" pot

... not for citation purposes)Vol 13 No 3ResearchInfra-red thermometry: the reliability of tympanic and temporal artery readings for predicting brain temperature after severe traumatic brain ... between brain and tympanic temperature readings are greater than for brain and temporal artery readings, i.e. the arrow to the right of the vertical line indicates that readings favour temporal artery ... pro-vided by 353 temperature 'triplets': brain and tympanic mem-brane readings, and brain and temporal artery readings. The temperature measurements were made by one member of the research...
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Báo cáo y học: "Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes." potx

... in synteny with (eithercopy of) the target gene, we could map it to the correct branchwhen one of the other teleosts had two copies of the bystandergene, and both were in synteny with their ... two copies of the bystander gene is still in synteny with the corresponding copy of the target gene in the fish genome. The code captures the relationship of the bystander orthologs and in-paralogs ... of opportunity' in which it is allowed for one part of the HCNE array to break off from one copy of the GRB, as long as the equivalent part of the array is still in cis to the other copy...
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Báo cáo y học:

Báo cáo y học: "What is the role of surfactant and inhaled nitric oxide in lung transplantation" pps

... reperfusion. Therefore, substitution of surfactant may bridge the patient to recovery of the graft. The combination of iNO and surfactant proved to be successfulin experimental severe reperfusion injury ... mind that the concept of ischaemia/reperfusion injury in clinical transplantation alsoembodies the state of the donor lung before harvesting and the quality of preservation, the method of lung ... injury and pulmonary oedema were the subject of numerous studies. The use of iNO as a means to ameliorate such injury byreduction in pulmonary vascular resistance, leucocytesequestration in the...
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Báo cáo y học:

Báo cáo y học: "Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models" pot

... representation of the CYP3A4-, CYP3A5- and UGT-catalyzed metabolic pathway for MDZFigure 1a) Schematic representation of the CYP3A4-, CYP3A5- and UGT-catalyzed metabolic pathway for MDZ. The percentages of ... for the hydroxyla-tion, normalized to the mean. There is no correlationbetween the CYP3A5 genotype and the affinity of MDZ toCYP3A (Km) or the rate of hydroxylation (Vmax) in the basal state.Figure ... respectively. Figure 6 represents the rank-order plot for the optimized 1OH_Km and 1OH_Vmax values for the Yu et al. [4] data. The result of this figure supports the hypothesis that CYP3A5 plays...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article Automatic Generation of Spatial and Temporal Memory Architectures for Embedded Video Processing Systems" docx

... only necessary for the designers to define the in-terfaces required by the filter, implement the filter, and spec-ify the required memory parameter. The architecture genera-tor then generates the ... SRAM and SDRAM at 150 MHz speed. The figure also il-lustrates the influence of the CAS latency on the performance for SDRAMs using a burst length (Bl) of 8. This latency canbe thought of as the ... between each of the five linepairs (the dashed line is the SRAM and the marked line is the SDRAM). The graph shows that the performance exceeds the HDTV performance 1367768 progressive mode for a tem-poral...
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Báo cáo y học: " Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice

... marrow and the gastrointestinal tissues from the cytotoxicity of CY in mice. We also profiled the changes of the expression of growth factors in gastric tissues in response to the damage by CY and ... denatured and separated by electrophoresis on a SDS-polyacrylamide gel (The percentage of the gel was 15% for VEGF, 15% for EGF, 10% for ODC and 10% for c-Myc protein). The protein was then transferred ... always clinically necessary in cancer patients receiving chemotherapy, so as to allow their immune systems to restore function [2]. On the other hand, the death of GI cells breaks down the physical...
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Báo cáo y học: "Update on the treatment of ocular toxoplasmosis"

... by Rothova et al was 250mg a day or 500mg every other day and therapy was associated with pyrimethamine 100mg on the first day that was fol-lowed by 50mg a day. Prophylaxy of recurrence of ... survey of the opinion of oph-thalmic specialists in uveitis was performed recently by Gary Holland. [3] The reasons that were commonly accepted to introduce a therapy were the following: a) the ... in the therapy of ocular toxoplasmosis. But the out-come was measured 4 weeks after initiation of ther-apy. Dihydrofolate reductase inhibitors (DHFR) have shown their efficacy in vivo in the...
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Báo cáo Y học: Ferritin from the spleen of the Antarctic teleost Trematomus bernacchii is an M-type homopolymer doc

Báo cáo Y học: Ferritin from the spleen of the Antarctic teleost Trematomus bernacchii is an M-type homopolymer doc

... ionmeter before and after the addition of the protein. After 24 h incubation at 20 °C, the samples were analyzed by CD,fluorescence spectroscopy, and size exclusion chromato-graphy.Spectroscopic ... in a soluble and availableform thereby protecting the organism against the toxic effect of ÔfreeÕ iron. The extremely stable quaternary structure of the ferritin molecule is highly conserved. ... alysis of atryptic digest of the protein indicated for the N-terminalpeptide MDSQVR a value of m/z 777, which points t o the presence of acetylme thionine. This r esidue is commonlyfound in the...
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Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx

Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx

... specificity of thisdomain, with residues Tyr91 and Tyr137 forminginteraction pocket 1; Tyr93, Tyr137 and Trp119 form-ing pocket 2, and the valley between n-Src and RTloops included by Trp119 and Tyr132 ... grooves 1 and 2 created by the n-Srcloop and the 310helix, stabilized by stacking interac-tions of the pyrrolidine ring of Pro7 with the aromaticside chain of Tyr137. Modelling of the PRD1-superpeptide, ... highlighted the importance of the Fyn SH3-domain interaction in initi-ating the association with PAG, and how this affectstyrosine phosphorylation and thereby the functionality of PAG as a...
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Báo cáo y học:

Báo cáo y học: "Hypoxia in the pathogenesis of systemic sclerosis" ppt

... procollagenprolyl hydroxylases (P4HA1 and P4HA2), lysyl oxidase (LOX) and lysyl hydroxylases (procollagen lysyl hydroxylase and procollagen lysyl hydroxylase 2). Similar links betweenhypoxia and fibrosis ... essential for the physiological regulation of cellular responses to hypoxia.Upregulation of prolyl hydroxylase domainactivity in chronic hypoxiaInterestingly, PHD2 and PHD3 are induced by hypoxia ... ODDD(positions 402 and 564) triggers the oxygen-dependent regu-lation of HIF-1α. This hydroxylation is catalyzed by a family of 2-oxoglutarate dependent dioxygenases called prolyl hydroxy-lase domains...
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