Báo cáo y học: "Collagen-related biomarkers in severe sepsis: a big stretch" pptx

... relatively rapid biomarker assays using multiplex [14] and antibody micro- array [15] technology may be widely available in the near future and yield critical severe sepsis prognostic information in ... system. Clin Chem 1997, 43:1749-1756. 15. Garcia BH, 2nd, Hargrave A, Morgan A, Kilmer G, Hommema E, Nahrahari J, Webb B, Wiese R: Antibody microarray analysis of inflammatory mediator...

Ngày tải lên: 13/08/2014, 16:20

... regard- ing the primary diagnosis - only CAS patients were con- sidered. It was performed over a one-year period eliminating any bias related to seasonal variation. Time 0 was clearly defined as ... design and acquisition of data and/or analysis and interpretation of data, as well as in the drafting, revising and final approval of the version to be published. Acknowledgements We are indeb...

Ngày tải lên: 13/08/2014, 20:22

... NAC infusion appear to be of vital importance. Most of the animal data were obtained in pretreatment or early post-treatment studies. In that way, they are of limited relevance to the clinical ... endotoxaemia in volume-resuscitated pigs. NAC significantly elevated glutathione concentrations but failed to improve gas exchange, metabolism and any systemic, pulmonary or hepatosplanchnic p...

Ngày tải lên: 12/08/2014, 20:20

... 158(6):1951-1957. 51. Takizawa H, Tanaka M, Takami K, Ohtoshi T, Ito K, Satoh M, Okada Y, Yamasawa F, Nakahara K, Umeda A: Increased expression of transforming growth factor-beta1 in small airway epithelium ... generated the CT data. TH and NL assisted in the statistical analysis. GJC, EAH, and FJM participated in generating the data and in data analysis. JJR helped design the stud...

Ngày tải lên: 12/08/2014, 11:20

Ngày tải lên: 12/08/2014, 23:24

... peptide – A window to the heart. N Engl J Med 2002, 347:158–159. 6. Tomaru Ki K, Arai M, Yokoyama T, Aihara Y, Sekiguchi Ki K, Tanaka T, Nagai R, Kurabayashi M: Transcriptional activation of the ... associated with an adverse postoperative outcome after cardiac surgery: a comparative study between coronary artery bypass graft, valve, and combined cardiac surgery. Crit Care 2007, 11:R106....

Ngày tải lên: 13/08/2014, 08:20

... resuscitation using pol- yethylene glycol-albumin- and hydroxyethyl starch-based plasma expanders. Shock 2005, 24:66-73. 14. Hangai-Hoger N, Nacharaju P, Manjula BN, Cabrales P, Tsai AG, Acharya SA, ... Seetharama A Acharya 3 , Marcos Intaglietta 1 and Amy G Tsai 1,2 1 Department of Bioengineering, University of California, San Diego, Gilman Dr, La Jolla, California 92093, USA 2 La Jolla...

Ngày tải lên: 13/08/2014, 10:20

... to manipulate inflammatory activation in a therapeutically useful manner. In any case, the results here indicate that COX-2 is degraded by calpain, and that PIN1 regulates its expression via effects ... ester]-threonine-pro- line-leucine-lysine~serine-proline-proline-proline-serine- proline-arginine-[5-((2-aminoethyl)amino)naphthalene- 1-sulfonic acid], and carboxybenzyl-phenylalanine-...

Ngày tải lên: 11/08/2014, 08:22

... Inotrope therapy must be titrated to a targeted response, such as improvements in Svc O 2 and in myocardial function indices, and a reduction in lactate. The combination of dobutamine and noradrenaline ... of haemodynamic support in sepsis? The different stages of sepsis are characterized by certain circulatory changes. Circulatory changes exist at both ‘macrovascular’ and ‘microv...

Ngày tải lên: 12/08/2014, 23:24

... certain circulatory changes. Circulatory changes exist at both ‘macrovascular’ and ‘microvascular’ (capillary) levels, but presently there is no way to monitor microcirculatory changes directly, and neither ... indices, and a reduction in lactate. The combination of dobutamine and noradrenaline stimulates both α 1 and β 2 adrenergic receptors, and it is recommended as first-line treatment...

Ngày tải lên: 12/08/2014, 23:24