Báo cáo y học: "Triggering receptor expressed on myeloid cells-1 expression on monocytes is associated with inflammation but not with infection in acute pancreatitis" pdf
... on blood monocytes is an indicator of inflammation but not of infection in patients with AP. • Low HLA-DR expression and high IL-6 concentration could predict severity and infection in samples ... inflammatory response syndrome and then by the compensatory anti-inflammatory response syndrome, which is defined by low human leukocyte antigen (HLA)-DR expression o...
Ngày tải lên: 13/08/2014, 16:20
... identify a stronger COX-2 antigen signal in the airway of mice not receiving the antisense oligonucleotide. In addition, since immu- nohistochemistry revealed that COX-2 expression was consistently ... to interpret. There is a general belief that AHR at least partly correlates with the underlying inflammatory process, since respiratory dysfunction is normally accompanied by airw...
Ngày tải lên: 12/08/2014, 14:20
... infection may include polymyositis, rhabdomyolysis, tumor infiltrations, wast- ing syndromes, severe weakness, and fatigue [2,3]. The pathogenesis of HIV-1 -associated myopathies is not fully understood, ... therapy with thiols such as S-adenosyl-methionine, N-acetylcysteine, or pro- cysteine may reduce the influences of oxidative stress and/ or redox-sensitive signaling pathways in...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Distinctive receptor binding properties of the surface glycoprotein of a natural Feline Leukemia Virus isolate with unusual disease spectrum" pps
... analysis implicates a single residue as the major determinant of binding phenotype To identify the residues within the VRB-containing seg- ment responsible for its influence on binding phenotype, a ... fluorescence intensities obtained in three replicate assays at each concentration by nonlinear regression analysis using saturation binding kinetics equations in GraphPad Prism5.0 (GraphP...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx
... construction of fusion proteins with maltose binding protein as a chaperone on the N-terminus and a C-terminal Ôsolubilization tagÕ.This system may allow large-scale production of those proteins that ... tendency to misfold during expression. Keywords: expression; fusion protein; precipitation; protein folding; solubility. Despite the widespread use of fusion protein-based over- expre...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt
... stimulation in the synovium. Taken together, inter- action between chemokine and chemokine receptor might play roles not only on B cell migration into the synovium, but also B cell activation in the ... ligation of the corresponding ligand chemokine. Alternatively, stimulation with cytokines or adhesion molecules may downregulate chemokine receptor expression in the synovi...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4+ and CD8+ T cells" pot
... dilution. Background fluorescence was measured following staining with the secondary antibody alone. Staining with the anti-carboxy terminal Glut-1 polyclonal antibody (generously provided by A. ... a primary binding receptor for HTLV on CD4 T lym- phocytes was based largely on their supposition that the Glut-1 transporter is not expressed on this lymphocyte subset [8]. Inde...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: " A tool for comparing different statistical methods on identifying differentially expressed genes" potx
... production of the corresponding enzymes and acetylCoA consumption in the cycle, thus improving acetylCoA availability for sterol biosynthesis. It is worth noting that the ACS2 (acetylCoA synthase) ... strain and ERG5 gene is present in the wild type but has been disrupted in the production strain. Phenotypically, the CA10/pCD63 strain differs by the deregulation of the galacto...
Ngày tải lên: 14/08/2014, 14:21
Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"
... role in study design; in the col- lection, analysis, or interpretation of data; in the writing of the report; or in submission decisions. None of the authors have any competing interests to dis- close. Authors' ... second difficulty, that continued beyond the immedi- ate crisis, was lack of money. No one had transport money and getting to the clinic was so difficult and people ha...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: " Effect of dose-escalation of 5-fluorouracil on circadian variability of it"
... treated with the standard dose is not recog- nized of the higher dose. The DPD activity is inhib- ited by 5-FU administration [22], and this might con- tribute to the increase in the concentration ... explained by the inhibition of DPD. In conclusion, the dose-escalation of 5-FU results in a preferable clinical response, especially in ad- vanced ESCC patients, and this is e...
Ngày tải lên: 26/10/2012, 09:39