Báo cáo y học: "Construction of Gene Regulatory Networks using biclustering and Bayesian networks" docx

... credibility of the network generated by analyzing the network topology using NetworkAnalyzer [36] and finding putative modules using MCODE [37] and BINGO [38]. Results and Discussion Biclustering ... networks that have learned using Bayesian networks [29]. A performance comparison of networks generated from learning corresponding biclustering algorithms...

Ngày tải lên: 13/08/2014, 16:20

... that cover X-boxes of the entire set of known target genes at the time (see Materials and methods). Four (RYYVYY N1-3 RRHRAC, GYTNYY N1-3 RRNRAC, GYTDYY N1-3 RRNRAC, GYTRYY N1-3 RRHRAC) were searched ... several genes as novel candidates for ciliogenesis. Our data are of particular importance for further genetic and genomic studies in the field of ciliogenesis and, consequently,...

Ngày tải lên: 14/08/2014, 08:20

... the conservation of syn- teny: the interdigitation of regulatory elements and their tar- get genes by other genes with unrelated functions and regulatory pathways [84,85]. None of those proposed ... information of mapped SNP markers (primer and probe sequences, gene annotation, and synteny)Detailed information of mapped SNP markers (primer and probe sequences, gene...

Ngày tải lên: 09/08/2014, 20:20

... = Ct (target gene of sample) - Ct (refer- ence gene of sample) ΔCt (calibrator) = Ct (target gene of calibrator) - Ct (reference gene of calibrator) Ratio (folds of difference) of sample: calibrator ... J, Yang Y, Mu YX, Liu M, Lu L, Li Y, Zhu Y, Wu J: Inhibition of Hepatitis B virus gene expression by single and dual small interfering RNA treatment. Virus Res 200...

Ngày tải lên: 12/08/2014, 01:21

... metabolically biotinylated Fab constructs can be genetically engineered to precisely control the num- ber and location of biotin residues on the antibody. Our lab has developed metabolically biotinylated ... targeted gene delivery. Findings The hAd5-based vector remains one of the most popu- lar vector systems for gene delivery and cancer gene therapy. However, the ubiquitous ex...

Ngày tải lên: 12/08/2014, 02:20

... replication specificity and/ or to modulate their cytopathogenicity. For instance, cytotoxic genes may be incorporated into the viral genome or virus spread may be improved by inclusion of genes encoding ... University of Amsterdam, Amsterdam, The Netherlands and 2 Department of Paediatric Oncology, Emma Children Hospital, Academic Medical Center of the University of Amsterdam,...

Ngày tải lên: 13/08/2014, 09:20

... Microarray analyses of PCOS samples from 2003 to 2007 Microarray study Number of differentially expressed genes The molecular phenotype of PCOS theca cells and new candidate genes defined by microarray ... [10]. However, none of those genes are likely to be the key players in the pathogenesis of PCOS because its complexity and heterogeneity suggest the involvement of many gene...

Ngày tải lên: 13/08/2014, 16:20

... identify and predict subsets of target genes potentially triggered by different regulatory pathways and thus possessing different regulatory modules. The meth- odology is easily applicable to any ... discovery of complementary pairs entails automatically the discovery of the corresponding subsets of sequences. We analyzed the distribution of the constituents of the found c...

Ngày tải lên: 13/08/2014, 22:22

... (7.4) ygcL (6.6) rcsF (6.3) yddK (5.7) ygaF (5.4) ynaJ (5.3) pdxA a (5.2) wzc (5.0) surA (4.9) rpe a (4.8) ygdD a (4.7) aroF (4.1) yadN (4.0) uvrY (4.0) yeeA (4.0) ydhH (3.9) yfhD (3.9) yadK ... reaction. Km r Km r Defined or random library Reference Selection Generation of flanks with biotinylated primer Polyadenylation Nested PCR (amino-allyl dUTP incorporation) Dye conjugation Mic...

Ngày tải lên: 14/08/2014, 07:21

... obtained directly from the source provider, and that history, exam, and differential diagnosis are central to the provision of portal -of- entry primary care as well as secondary specialty care. They noted ... point of referral may depend on the familiarity or relationship between the providers, and that the nature of the referral (e.g., amount and type of information accompan...

Ngày tải lên: 25/10/2012, 10:06