Báo cáo y học: " Mathematical model insights into arsenic detoxification" pptx
Báo cáo y học: " Mathematical model insights into arsenic detoxification" pptx
... article as: Lawley et al.: Mathematical model insights into arsenic detoxification. Theoretical Biology and
Medical Modelling 2011 8:31.
Lawley et al. Theoretical Biology and Medical Modelling 2011, ... inorganic arsenic
LiAs-stor liver storage of inorganic arsenic
LMMAs liver monomethyl arsenic
LDMAs liver dimethyl arsenic
LDMAs-stor liver storage of dimethyl arsenic
UiAs...
Báo cáo y học: "Phosphoproteomics: new insights into cellular signaling" pptx
... The availabil-
ity of genome databases and advancements in analytical
technology, especially mass spectrometry, has made it
possible to study many phosphoproteins and phosphorylation
sites at ... and the discovery of new phos-
phorylation sites in known signaling proteins. As enzymatic
catalysis by protein kinases is the only known physiological
mechanism for phosphorylation of serine, ... ph...
Báo cáo y học: "Genome-wide insights into eukaryotic transcriptional control" doc
... complete redundancy, quantitative redun-
dancy, and incongruent redundancy. e latter category
was unexpected yet is relatively common and can arise
from partial redundancy between two factors ... treatment. e sensi-
tivity of this approach meant that they could identify
about tenfold more protein-coding genes rapidly
regu lated by estrogen than did microarrays. Moreover,
the data revea...
Báo cáo y học: " mathematical model of brain glucose homeostasis" doc
... mainly due to the fact that the brain is uniquely
dependent on the availability of glucose and that dysglyc-
emia, either hypoglycemia or hyperglycemia, would
induce brain dysfunction. Not only ... glucose utilization by erythrocytes, which is
assumed to occur only in the arterial compartment for
simplification, although the glucose is physiologically uti-
lized by erythrocytes in all blood ....
Báo cáo y học: " Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction" pot
... rouleaux,
assuming that viscosity is determined by the numbers of
erythrocytes only at a high yield velocity (since high yield
velocities destroy rouleaux). Granted this assumption, the
viscosity is determined ... resemble
those of a solid body. When the yield velocity increases,
the length of the rouleaux gradually decreases and ulti-
mately only stand-alone erythrocytes are left.
To test th...
Báo cáo Y học: O-GalNAc incorporation into a cluster acceptor site of three consecutive threonines Distinct specificity of GalNAc-transferase isoforms pot
... transferred N-acetylgalactosamine into
the second Thr residue only when N-acetylgalactosamine
was attached to the third one.
Keywords: O-glycosylation; mucin; polypeptide N-acetylga-
lactosaminyltransferase; ... UDP-GalNAc.
Biosynthesis of O-glycans is mediated by the step-wise
addition of monosaccharides by a variety of glycosyl-
transferases, where topology and kinetic properties of
Golgi...
Báo cáo Y học: A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor docx
... a
three-dimensional model of the ligand binding domain
(LBD) of the mouse aryl hydrocarbon receptor (mAhR).
The model allowed us to putatively i dentify the residues
responsible for the recognition of polychlorinated ... by AhR receptors and to formulate an
hypothesis on the signal transduction mechanism.
Keywords: aryl h ydrocarbon receptor; polychlorinated
dibenzo-p-dioxins; structure p...
Báo cáo y học: "Put your heart into the joint benefits of statins" pps
... 3-hydroxy-3-methylglutaryl-coenzyme A; IFN = interferon; i.p. = intraperitoneally; LPS = lipopolysaccharide; Th = T helper cell; TNF =
tumour necrosis factor.
Arthritis Research & Therapy ... both capacities. Statins are particularly topical in
this regard.
Statins (3-hydroxy-3-methylglutaryl-coenzyme A [HMG-
CoA] reductase inhibitors) are widely prescribed for indi-
viduals at increased...
Báo cáo y học: "A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANK" pps
... part,
mediated by IL-1 and/or TNF-α.
Oncostatin M (OSM), a cytokine produced by activated T
cells and macrophages, is structurally and functionally
related to the IL-6 cytokine family. Raised levels ... Shaughnessy
SG: Stimulation of osteoclast differentiation in vitro by mouse
oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and
interleukin 6: synergy with dexamethasone. Cytokine 2...
Báo cáo y học: "A model of anti-angiogenesis: differential transcriptosome profiling of microvascular endothelial cells from diffuse systemic sclerosis patients" potx
... pool with NHS-cyanine dyes (Cy3 and Cy5;
Amersham Biosciences, Amersham Place, England). The two
labeled probes were hybridized with the array for 16 h at 65°C.
Arrays were scanned by using a 4000B ... 2:737-744.
7. Whitfield ML, Finlay DR, Murray JI, Troyanskaya OG, Chi JT, Per-
gamenschikov A, McCalmont TH, Brown PO, Botstein D, Connolly
MK: Systemic and cell type-specific gene expression p...
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