Báo cáo y học: " The function of 7D-cadherins: a mathematical model predicts physiological importance for water transport through simple epithelia" pdf

... 8:18http://www.tbiomed.com/content/8/1/18Page 6 of 12RESEA R C H Open Access The function of 7D-cadherins: a mathematical model predicts physiological importance for water transport through simple epitheliaMareike Ahl1,2, Agnes ... analytical characterization of the model as well as the literature search for the necessary parameters. AW performed the electron microscopy of the mouse gut. SW characterized the analyticalproperties ... Germany.2Department of Mathematics I, RWTH-Aachen University, Aachen, Germany.3Lehrstuhl A Mathematik, RWTH-Aachen University,Aachen, Germany.Authors’ contributionsMA did most of the calculations and the analytical...

... modi®ed plasmids and selection of t ransfor-mants was performed as described above.Computer analysisDatabase searches made use of the programBLAST[31].Search for membrane-spanning helices was ... membrane f raction and from the liposomes. The activity of polysul®de respiration with H2increased hyper-bolically with the amount of MM. The activity was 50 a nd80% of the maximum activity ... tandard. MK4(Sigma; c at. no. V-937 8) and v itamin K1(Fluka; cat. no.95271) are commercially available.Activities of Psr and of polysul®de respiration The activity of Psr was measured at...

... wrote the manuscript. TT collected and analysed data. IF participated in the design of the study, analysed data and reviewed the manuscript. MGN analysed dataand performed the statistical analysis. ... statistical analysis. VP analysed data and reviewed the manuscript. CY collected and analysed data. SR analysed data. YK reviewed the manuscript. All authors reviewed and approved the manuscript.Competing ... interaction wasobtained, pairwise comparisons were performed through simple contrasts and simple main effects analysis. Oneway ANOVA was used to analyze time to exhaustion,carbohydrate and fat...

... some associations being correlativerather than causative. The potency of the biologicallyactive metals is likely to vary, for example, Riley et al.[22]was able to rank metal toxicity to rat ... bycytospot preparations. These were stained with Diff Quick(Lamb) before determination of differential cell counts.BAL biochemical analysis The primary BAL from each rat was analysed for markers of ... periods. Of metals analysed, iron was most abundant in the total and acid extract, while zinc was the most prevalent metal in the water- soluble fraction. Elevated markers of inflammation included a...

... 127:47-54.26. Asturias JA, Gomez-Bayon N, Arilla MC, Sanchez-Pulido L, Valencia A, Martinez A: Molecular and structural analysis of the panal-lergen profilin B cell epitopes defined by monoclonal anti-bodies. ... 132:258-262.31. Al-Dowaisan A, Fakim N, Khan MR, Arifhodzic N, Panicker R,Hanoon A, Khan I: Salsola pollen as a predominant cause of respiratory allergies in Kuwait. Ann Allergy Asthma Immunol 2004,92:262-267.32. ... 1:6). Assecondary antibody either HRP-labelled goat anti-humanIgE (Bethyl Laboratories, Montgomery, USA, Cat no A8 0-108P), or a dual antibody combination of mouse mono-clonal anti-human IgE (AbD...

... for spermatogenesis.ACKNOWLEDGEMENTSWe wish to thank the staff from the Laboratory Animal Center,Yamagata University School of Medicine, for taking care of the rats.Supported in part by a Gran t-in-Aid for ... NADPH oxidation and other red uctases in the samples can be ignored. One unit of GR activity was d efinedas the amount of enzyme that catalyzes the oxidation of 1 lmol of NADPH per min. All assays ... YamagataUniversity School of Medicine, 2-2-2 Iida-nishi, Yamagata City,Yamagata 990-9585, Japan. Fax: + 81 23 628 5230,Tel.: + 81 23 628 5227, E-mail: jfujii@med.id.yamagata-u.ac.jpAbbreviations: GR, glutathione...

... contributionsAP was the primary author and carried out data collection, analysis of bloodsamples, and statistical analysis. JG and AT helped collect data. AB assistedwith statistical analysis. JL and ... of variance (ANOVA).POMS data were analyzed using a 2 × 3 (treatment ×time) RM multiple analysis of variance (MANOVA).Serum cortisol and total testosterone data were analyzedusing separate ... assisted with analysis of POMS and SSTdata. MG and RK assisted with manuscript preparation. MB, JO, SS, and CRassisted with analysis of blood samples. All authors read and approved the final...

... ACGTTGGATGAGAGAACTGGGTTAAGGCAGrev ACGTTGGATGCCAGCACATCTTTTCACTCCACTCCATACCACTGGTCAGCTG 93.81ST+7 rs574174 G /A 0.19 0.19 fwd ACGTTGGATGCTGCCCTTGATGATTCCAAGrev ACGTTGGATGGGAACATCACAGGAAATGACACTGTCCCCATCCCATC ... ACGTTGGATGTTGCTCAGCCCCAAAGATGGCCCCACAGCCACTGGACAG 93.95V4 rs2787094 C/G 0.22 0.23 fwd ACGTTGGATGAGAAACAGGAAGGAAGGTCCrev ACGTTGGATGTATGGTTCGACTGAGTCCACCTGAGTCCACACTCCCCTG 93.84Respiratory ... ACGTTGGATGAGTCGGTAGCAACACCAGGrev ACGTTGGATGACCATGACACCTTCCTGCTGGCTGCCTCTGCTCCCAGG 91.88ST+4 rs44707 A/ C 0.41 0.41 fwd ACGTTGGATGGGAGTGAAAAGATGTGCTGGrev ACGTTGGATGCCACTTCCTCTGCACAAATCACAAATCACCTCTGTCACCC...

... RVafterload is probably counterbalanced by the effect of a highintrathoracic pressure. The RV afterload was not increased by the application of OLCventilation. The mean arterial pulmonary pressure ... dramati-cally affects the capability of the scanner to distinguish a voxelFigure 3Computed tomography scan examples of basal lung areasduring expirationComputed tomography scan examples of basal lung areasduring ... Foley catheter.Fluid management during the study was based on the REDVprovided by the pulmonary artery catheter. The REDV beforelung lavage was considered the optimal REDV. After lung lav-age...

... 4b[4ab] A4 cabTGTACCAATTGCTAATTGTAA A AAAGTGTTGCTTTTCA A TTGCCAAAGTTTGTTTCA A TGA A CAAAAAGCCTTAAG[4ab][4ab] A3 ACATATCTATGAAACTTATGGGGATACTTGGGCAGGAGTGGAAGCCATAA A TAA A GAATTCTGCAACAACTGCTGTTTATCCATTTCAAG32 A2 ACCCTGAATTAGCAGGACCAACTAATTCATCTGTATTACTTTGACTGTTTTTCAAG1 A1 TAGCAACAGACATACAAA A CTAAAGAATTACAAAAACAAATTACAAAAATTCAAAATTTTCGGGTTTATTACAAG A1 ex A2 exD4 A SV-SD4/RRE/SA-pA A3 ex A5 ex A7 exISS A4 cab5ex A4 cabAGGGACAGCAGAGATCCAGTTTGGAAAGGACCAGCAAAGCTCCTCTGGAAAG1AGACTCTGCTATAAGAAAGGCCTTATTAGGACACATAGTTAGCCCTAGGTGTGAATATCAAGCAGGACATAACAAG2ESSV AGAATTGGGTGTCGACATAGCAGAATAGGCGTTACTCGACAGAGGAGAGCAAGAAATGGAGCCAGTAGATCCTAGACTAGAGCCCTESS2 ... 4b[4ab] A4 cabTGTACCAATTGCTAATTGTAA A AAAGTGTTGCTTTTCA A TTGCCAAAGTTTGTTTCA A TGA A CAAAAAGCCTTAAG[4ab][4ab] A3 ACATATCTATGAAACTTATGGGGATACTTGGGCAGGAGTGGAAGCCATAA A TAA A GAATTCTGCAACAACTGCTGTTTATCCATTTCAAG32 A2 ACCCTGAATTAGCAGGACCAACTAATTCATCTGTATTACTTTGACTGTTTTTCAAG1 A1 TAGCAACAGACATACAAA A CTAAAGAATTACAAAAACAAATTACAAAAATTCAAAATTTTCGGGTTTATTACAAG A1 ex A2 exD4 A SV-SD4/RRE/SA-pA A3 ex A5 ex A7 exISS A4 cab5ex A4 cabAGGGACAGCAGAGATCCAGTTTGGAAAGGACCAGCAAAGCTCCTCTGGAAAG1AGACTCTGCTATAAGAAAGGCCTTATTAGGACACATAGTTAGCCCTAGGTGTGAATATCAAGCAGGACATAACAAG2ESSV ... 4b[4ab] A4 cabTGTACCAATTGCTAATTGTAA A AAAGTGTTGCTTTTCA A TTGCCAAAGTTTGTTTCA A TGA A CAAAAAGCCTTAAG[4ab][4ab] A3 ACATATCTATGAAACTTATGGGGATACTTGGGCAGGAGTGGAAGCCATAA A TAA A GAATTCTGCAACAACTGCTGTTTATCCATTTCAAG32 A2 ACCCTGAATTAGCAGGACCAACTAATTCATCTGTATTACTTTGACTGTTTTTCAAG1 A1 TAGCAACAGACATACAAA A CTAAAGAATTACAAAAACAAATTACAAAAATTCAAAATTTTCGGGTTTATTACAAG A1 ex A2 exD4 A SV-SD4/RRE/SA-pA A3 ex A5 ex A7 exISS A4 cab5ex A4 cabAGGGACAGCAGAGATCCAGTTTGGAAAGGACCAGCAAAGCTCCTCTGGAAAG1AGACTCTGCTATAAGAAAGGCCTTATTAGGACACATAGTTAGCCCTAGGTGTGAATATCAAGCAGGACATAACAAG2ESSV...