Báo cáo y học: "Maximum likelihood estimation of reviewers’ acumen in central review setting: categorical data" pdf

... CCG-945 In the CCG-945 study [11], sections of study tum ors were centrally reviewed, initially by a study review neu ropathologist and subsequently by 5 neuropathologists, including the review ... Maximum likelihood estimation of reviewers’ acumen in central review setting: categorical data. Theoretical Biology and Medical Modelling 2011 8:3. Submit your next manu...

Ngày tải lên: 13/08/2014, 16:20

... Foundation of America. Matthew Lee (Intel Scientific Award winner) currently is in the New York University. He is involved in the investigation of Apoptosis inhibitor expression in the hepatoma ... involved in the investigation of the role of HBV proteins in the up-regulation of apoptosis inhibitor. Timothy Block Ph. D is a Professor, director of Drexel Institute for...

Ngày tải lên: 02/11/2012, 11:17

... (p=0.04) of CVD by multiple logistic regression analysis using the above risk factor variables. In conclusion: a) hypoalbuminaemia is an independent predictor of CVD in early CKD stages; b) hypoalbu- minaemia ... events in this population (27). In a re- cent study C-reactive protein and low albumin has been shown to be the predictor of morbidity and mor- tality in CKD 3-5 pa...

Ngày tải lên: 03/11/2012, 11:52

... 1, t ype 2 A a nd type 2C, in contrast, a re highly active against phosphohistidine in histone H4 (reviewed in [1]). Intriguingly, none of the serine/threonine phosphatases acting on histidine ... disappearance of phos- phohistidine on P-selectin are very rapid. The next finding of an intracellular signaling system involving histidine phosphorylation in mammals appeared in 2000...

Ngày tải lên: 24/03/2014, 03:21

... 42% of children were diagnosed with AR by the age of 6 years. The prevalence of AR has increased dramatically in the past 30 years and continues to increase. Children with one component of atopy ... greater risk of developing a second component. 2 In 1998, the Joint Task Force on Practice Parameters in Allergy, Asthma, and Immunology defined rhinitis as ‘‘inflammation of the...

Ngày tải lên: 08/08/2014, 21:20

... by: Coincidental appearance of psychotic symptoms in members of a family while living together Appearance of psychotic symptoms in two closely associated persons Transmission of psychotic symptoms ... entity than the one described by Lasègue. This includes a wider range of psychiatric conditions in the primary, the possibility of psychiatric morbidity in the secondary, sus...

Ngày tải lên: 08/08/2014, 21:20

... and/or treat predisposing factors such as vitamin D deficiency, which is commonly found in this type of patient. The majority of the 1,497 minor injuries consisted of bruising (40%), wounds (35%) ... study of accidents occurring in mentally handicapped patients living in institutions Annals of General Psychi- atry 2010, 9:22 Received: 7 November 2009 Accepted: 8 May 2010 Pub...

Ngày tải lên: 08/08/2014, 23:21

... arginine residues in IS4V H As reported previously, the presence of the heavy chain of IS4 plays a dominant role in binding to CL [29]. IS4V H binds CL in combination with six of the 10 light chains tested ... sequence of IS4V H was dominant in con- ferring the ability to bind cardiolipin (CL) while the identity of the V L paired with this heavy chain was important in de...

Ngày tải lên: 09/08/2014, 06:22

... between indexes of severity and dynamic MRI in either PsA and RA. This last finding is surpris- ing in view of our previous results on the high correlation between clinical and laboratory indexes of ... significantly higher in PsA than in healthy controls, with only one case of overlap between the two conditions. A more efficient way of differentiating PsA from RA by MRI is...

Ngày tải lên: 09/08/2014, 06:22

... abnormal central pain mechanisms to clinical FM pain include temporal summation of pain (or windup) and central sensitization. Review Biology and therapy of fibromyalgia: pain in fibromyalgia syndrome Roland ... the contribution of peripheral pain to overall clinical pain in FM [26]. In a large study of FM patients, ratings of peripheral pain areas accounted for 27% of...

Ngày tải lên: 09/08/2014, 08:22