Báo cáo y học: "Critical illness hyperglycemia: is failure of the beta-cell to meet extreme insulin demand indicative of dysfunctio" pot
Báo cáo y học: "Critical illness hyperglycemia: is failure of the beta-cell to meet extreme insulin demand indicative of dysfunctio" pot
... resistance (Preissig and Rigby’s argu- ment), or whether the higher exogenous insulin required to bring these patients to target is indicative of higher resis- tance. Discerning whether beta-cell ... peripheral insulin sensitivity and beta-cell function. In the authors’ data, the issue becomes whether the low C-peptide levels in the RF+CVF group are indicative o...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "Critical illness-related corticosteroid insufficiency in patients with severe acute biliary pancreatitis: a prospective cohort study" pot
... to 90) 58 (57 to 60) 84 (79 to 93) < 0.001 SOFA score on the day of SST 5 (3 to 9) 11 (7 to 15) 4 (2 to 6) < 0.001 APACHE II score on the day of SST 15 (10 to 20) 20 (10 to 27) 15 (11 to ... mortality in the present study was characterized by MODS in which respiratory dysfunction was accompanied by dysfunction of other organ systems. MODS occurring in the...
Ngày tải lên: 13/08/2014, 18:22
Tài liệu Báo cáo Y học: Ornithine decarboxylase-antizyme is rapidly degraded through a mechanism that requires functional ubiquitin-dependent proteolytic activity pot
... In this biosynthesis pathway ornithine is decarboxylated to form putrescine by the action of ornithine decarboxylase (ODC, EC 4.1.1.17). Next an aminopropyl group generated by the action of S-adenosylmethionine ... inde- pendently of ODC raised the possibility t hat antizyme may be degraded via different recognition machinery. The major cellular proteolytic system responsibl...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo y học: "Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin" pptx
... suggest that the pathology of RA within the first few months after symptom onset is distinct from that of other early inflammatory arthritides and of established RA. The nature of the cytokines present ... subsequently at clinical follow up. In one of the few other studies of the pathology of very early inflammatory arthritis, synovial histology was assessed in 24...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf
... pathways may be required to prevent or reduce the development of inflammatory arthritis. One potential factor that bridges the two apoptotic pathways is the BH3-only protein Bid. To this end, we ... apoptosis [21]. These events are prevented by the overexpression of Bcl- 2/Bcl-x L or by the complete ablation of Bax and Bak [22]. The induction of apoptosis mediated b...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies" pot
... (13) History of stroke or TIA, n (%) 174 (10) 321 (12) 137 (12)* History of vascular disease, n (%) 770 (43) 1220 (45) 502 (45) History of angina, n (%) 484 (27) 740 (27) 290 (26) History of claudication, ... cardiovascular mortality may be missed, because patients dying of CVD earlier in the disease course are not part of their cohort. This hypothesis was corroborated by our re...
Ngày tải lên: 12/08/2014, 11:23
Báo cáo y học: "Plasma redox status is impaired in the portacaval shunted rat – the risk of the reduced antioxidant ability" doc
... produced by Kupffer cells [37,38]. Upregulation of this cytokine may be related to the enhanced respiratory burst activity of Kupffer cells leading to the redox activation of NF-κB [39-41]. This compensatory ... peroxidation is not produced, therefore it can be suspected that the novo antioxidant synthesis is reduced. If so, the reduction of the systemic antioxidant...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: "Suicide risk in schizophrenia: learning from the past to change the future" pot
... with a family history of suicide who were com- pared with 5,602 patients with no family history of sui- cide. A family history of suicide was found to significantly increase the risk for an attempt ... controlled trials of psychotherapy and concluded that reality-orientated psychotherapy is superior to a dynamic, insight-orien- tated approach. Nevertheless, exploratory psychot...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13" ppsx
... chondrocytes have been shown to produce a host of cytokines and inflammatory mediators, many of which are also produced by monocytes/macrophages [27]. IL-7 can be added to this list of mediators. ... soluble IL-6 receptor (necessary to stimulate chondro- cytes with IL-6), or the combination of the cytokines. Indeed, the combination of the cytokines together was require...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: " ZINBA integrates local covariates with DNA-seq data to identify broad and narrow regions of enrichment, even within amplified genomic region" doc
... exten- sion of Poisson distribution to handle over-dispersion, that is, the situation where the variance of the counts is larger than expected by a Poisson distribution. Instead of using a single Poisson ... Genome Biology 2011, 12:R67 http://genomebiology.com/2011/12/7/R67 Page 12 of 20 for the analysis of TFBS ChIP-seq, are not well-suited to the analysis of thi...
Ngày tải lên: 09/08/2014, 23:20