Báo cáo y học: "Modeling the clonal heterogeneity of stem cells" doc

... FEBS 2004 Modeling < /b> the < /b> Q o site < /b> of < /b> crop < /b> pathogens < /b> (Eur. J. Biochem. 271) 2269 Modeling < /b> the < /b> Q o site < /b> of < /b> crop < /b> pathogens < /b> in < /b> Saccharomyces < /b> cerevisiae < /b> cytochrome < /b> b Nicholas Fisher 1 , Amanda C. Brown 1 , ... pyraclostrobin. The < /b> sidechain of < /b> F275 in < /b> chicken bc 1...

Ngày tải lên: 16/03/2014, 16:20

... Arg16 and Glu20. The biological impact of the Aib1 5 and D -Phe12 modifications on the synthetic CRH analogue is illustrated by the peptide binding affinity enhancement towards the CRH receptor and ... towards the design and synthesis of new molecules with higher binding affinity and enhanced stability against biological degradation and possibly biological ac...

Ngày tải lên: 17/03/2014, 10:20

... build the atomic model of Neurospora crassa plasma membrane H + -ATPase, using as template the 2 .6 A ˚ crystal structure of rabbit sarcoplasmic reticulum C a 2+ -ATPase [Toyoshima, C., Nakasako, ... partially accessible to the solvent and m ay therefore act as a gate for the possible exit of a water- coordinated proton occurring at the extra-cytoplasmic end...

Ngày tải lên: 23/03/2014, 21:20

... with 2 lg of the reporter plasmid pCAPCAT, and either 0.5 lg of each of the clones of the overlapping AcMNPV k library or 1.0 lg of each plasmid of the overlapping lef library as described by Passarelli ... focus of this paper was to further elucidate the roles of replication LEFs and the nature of the AcMNPV replication complex by studying their inte...

Ngày tải lên: 23/03/2014, 21:20

.. . antisense oligonucleotides. Eur. J. Pharm. Biopharm. 50, 101–10 9. 1 0. Gamper, H.B., Parekh, H., Rice, M.C., Bruner, M., Youkey, H. & Kmiec, E.B. (2000) The DNA strand of chimeric RNA/ DNA oligonucleotides .. . mutagenesis of the factor IX gene by chimeric RNA/ DNA oligonucleotides. Nat. Med. 4, 285–29 0. 2 8. Kren, B.T., Parashar, B., Bandy...

Ngày tải lên: 31/03/2014, 08:20

... immune-modulatory potential. Five statins are currently available within the UK: pravastatin, simvastatin, fluvastatin, atorvastatin and rosuvastatin; in addition, lovastatin is available in other countries. ... whereas fluvastatin, atorvastatin and rosuvastatin are entirely synthetic [1]. Lovastatin and simvastatin are of the lactone Review Do the pleiotropic effects of...

Ngày tải lên: 09/08/2014, 06:22

... predominantly the tunica intima consisting of the endothelial layer and the basement membrane, and αSMA (e, f) staining predominantly the tunica media consisting of the muscular layer of the ... staining in the infrapatellar fat pad (IPFP) tissue vasculature. 3G5 (a, b) staining predominantly the tunica adventitia consisting of supporting tissue in the vascu...

Ngày tải lên: 09/08/2014, 10:23

... p300, to primary response genes to maintain an active chromatin acetylation signature. Inducible transcription factors then recruit different acetylases that modify a different set of lysines on the ... respec- tively, were acetylated in the unstimulated cells, only 3% (two genes) of the promoters of primary response genes became transiently acetylated at 0.5 h followi...

Ngày tải lên: 09/08/2014, 20:20

... complementary to the projects in UNICORN, showing how the systematic comparative analysis of core and accessory genes of chytrids can shed light on the origin of complex eukaryotic features such as the ... parasite of members of the family Resedaceae. The sequences of metagenomes - the total DNA of microbial populations of environmental samples - allows acc...

Ngày tải lên: 09/08/2014, 20:21

... the early expression of PAX6 in humans (similar to their previous results with rhesus monkey embryonic stem cells), may have been a step in the evolution of the highly evolved forebrain of ... dataset they gener- ated to compare the gene-expression profile of human embryos with that of human embryonic stem cells (hESCs) maintained in culture. ey found that ap...

Ngày tải lên: 09/08/2014, 20:22

... purposes) Implementation Science Open Access Research article Investigating the complementary value of discrete choice experiments for the evaluation of barriers and facilitators in implementation research: a ... complemen- tary value for the evaluation of barriers and facilitators, the choice of implementation strategy will be base...

Ngày tải lên: 11/08/2014, 05:21

... sampling of values of f 11 (the efficacy of the first treatment for the first clone, on the x axis. The results for various values of f 22 , the efficacy of the second treatment for the second ... analysis, there is no fixed order of extinction, but rather we demonstrate the existence of a mathematical con- struct (2.6) that expresses the switching ability am...

Ngày tải lên: 13/08/2014, 16:20

... desired to find the value of BMD as a function of the duration and the dose of LT4 therapy. Any remaining factor can be regarded as a special case of a variable with unchanging numerical val- ues, ... The aim was to evaluate the rate of bone loss and to assess whether calcium supple- mentation with or without intranasal calcitonin was able to decrease the...

Ngày tải lên: 13/08/2014, 16:21

... from the plasma membrane to the nucleus is the compartmentali- zation of signal transducers into quantal endocytic mem- brane-associated signaling packets that are retrogradely transported along ... previous observations suggesting that the signaling endosome hypothesis is a subset of a more general hypothesis that the most efficient mechanism for intracellular si...

Ngày tải lên: 13/08/2014, 23:20

... (e) an untreated planarian and (f) a planarian 6 days after 30 Gy X-ray treatment. Expression of the EST clone 32902158 (TAF-Ibeta1) in (g) an untreated planarian and (h) a planarian 6 days after ... factors (Additional data file 6). Validation of the array data To define the validity and accuracy of our global microarray analysis, we undertook two different approaches: qua...

Ngày tải lên: 14/08/2014, 20:22