Báo cáo y học: "A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia" ppsx
Báo cáo y học: "A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia" ppsx
... determine thepotential efficacy of recombinant human tissue factor pathway inhibitor (tifacogin) in a subpopulation of patients with community-acquired pneumonia (CAP) from a phase III study of severe ... Uchiba M, Okabe H, OkabeK, Yamaguchi Y: Recombinant tissue factor pathway inhibitor reduces lipopolysaccharide-induced pulmonary vascularinjury by inhibiting leukocyte activation. Am J Respir ... Platelet-Activat-ing Factor Acetylhydrolase in Severe Sepsis Investigators: Recombinant human platelet-activating factor acetylhydrolasefor the treatment of severe sepsis: results of a phase III,...
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Báo cáo y học: "Relative effectiveness and adverse effects of cervical manipulation, mobilisation and the activator instrument in patients with sub-acute non-specific neck pain: results from a stopped " ppt
... point.Pain decreased by 3 points in the Activator group, 4points in the manipulation group, and 3 points in themobilisation group. A reduction in pain of at least 2points is considered a clinically ... RI, Grodin AJ: Myofascial Manipulation: Therapy and Clinical Application. Austin, Pro-Ed 2001.91. McPartlan JM, Simons DG: Myofascial trigger points: Translating molecular theory into manual ... treatment with any of theinterventions during 6 months prior to recruitment to thestudy; specific neck pain due to fracture, neoplasm, infec-tion, inflammatory arthropathy, radiculopathy or myel-opathy;...
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Báo cáo y học: "Antibodies to cyclic citrullinated protein and erythrocyte sedimentation rate predict hand bone loss in patients with rheumatoid arthritis of short duration: a longitudinal study" pdf
... widely used in daily clinical practice. Theobjective of this longitudinal study was to examine if theseserological markers also predict hand bone mineral density(BMD) loss in patients with RA of ... latemeasure of bone involvement in RA [13].The objective of this study was to examine if serological mark-ers widely used in daily clinical practice also can predict earlyinvolvement of bone measured ... Support) study, a Norwegian arm of the cohort was followed longitudinally. At inclusion in 1992,238 patients aged from 20 to 70 years, with a clinical diagno-sis of RA and disease duration of less...
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Báo cáo y học: "A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α" potx
... Alternatively, this single amino acid substitu-tion might influence the configuration of surroundingloops by the changes in the side chain and polarity with- out directly involving the binding site of ... efficiently in CM cells but ineffi-ciently in human cells, we succeeded in rescuing theimpaired replicative capability of the virus in human cells.Sequence analysis of the MA-CA region of the ... capability in human cells. We thus concluded thatthe recovered replicative capability in human cells wasmainly the result of acquisition of the single amino acidsubstitution at the 116th position of...
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Báo cáo y học: "Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis." ppt
... is induced by AGE,can contribute to the inflammatory cycle by the induction of proinflammatory cytokines, via the nuclear factor- κB pathway [21]. No studies have yet examined RAGEexpression in ... specific type of AGE) were previously found to correlate with increased clini-cal disease activity in RA and with RF levels [6–11].However, in the present study no clinical parameter of jointdisease ... approximately 70% of patients with RA. Indeed, they have become an integralpart of the definition of this disease, despite the fact thatRFs are found in a small percentage of normal individuals,often...
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Báo cáo y học: "Respiratory and haemodynamic changes during decremental open lung positive end-expiratory pressure titration in patients with acute respiratory distress syndrome" docx
... system, decreased. These findings of rel-ative haemodynamic stability during the RMs are in line with those reported in the ARDS Network study [4,38] showing a10.6 ± 1.2 mmHg decrease in systolic ... compliance of the respira-tory system (Cdyn). Cdyn was automatically calculated asVtinsp/EIP – PEEP. The graphical display of Cdyn will indicatethe response of the patients& apos; respiratory system ... waseffective in improving respiratory system mechanics and oxy-genation in patients fulfilling standard ARDS criteria [21,27]while already being ventilated with low tidal volume and highPEEP. No clinically...
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Báo cáo y học: "Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity" docx
... derivate inhibited HIV-1 entry only into T cells Evaluation of C14 efficiency to inhibit limit the entry of HIV-1 into primary cellsFigure 4 Evaluation of C14 efficiency to inhibit limit the entry of ... France),respectively. Human recombinant macrophage-colonystimulating factor (rhM-CSF), granulocyte-colony stimu-lating factor (rhM-CSF), interleukin-4 (rhIL-4) and inter-leukin-2 (rhIL-2) were obtained ... anti-HIV-1 activity and cytotoxicityagainst a variety of tumor cell lines comparable to someclinically used drugs [8]. Two classes of chemically modi-fied BA derivatives are reported to inhibit HIV-1...
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Báo cáo y học: "A quantitative evaluation of gross versus histologic neuroma formation in a rabbit forelimb amputation model: potential implications for the operative treatment and study of neuromas" ppt
... fundamental prin-ciple of neuroma surgery involves excising the injurednerve segment proximally to the level of grossly n ormalfascicles. Yet the zone of injury of a peripheral nerve end-ing in a ... backmore proximally on the nerve stump, beyond theappearance of grossly normal-appearing fascicles, maybe beneficial during neuroma surgery in symptomatic patients. Employing the use of intra-operative ... days after injury, with onlyslightly increased myelinated fiber numbers [41]. OurfindingsaremoreconsistentwiththoseofAitken,whodemonstrated that in the nerve to the gastrocnemiusmuscle of...
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Báo cáo y học: "A Practical Approach to Management of Chronic Hepatitis B"
... made in managing HBV infection, challenge remains in optimizing HBV therapy. First, further understanding HBV dynamics and correlation of the level of HBV replication with liver injury will be invaluable ... Activity and Stage Liver biopsy provides us with valuable information of histological activity and stage of HBV disease in patients with HBV infection. It is known that patients with chronic HBV infection ... hepatic inflammation carry a significantly higher risk of disease progression. Histological staging of HBV disease is clinically very valuable in assessing degree of fibrosis and predicting disease...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... ±Birkprotease inhibitors [5], metallothioneins [6], prothymosina [7], a bacterial ®bronectin-binding protein [8], the brainprotein a-synuclein together with the related proteinsb-synuclein and c-synuclein ... scanning cal-orimetry, of bovine b-andj-casein, recombinant human a-,b-andc-synuclein, together with the A30P and A53T mu-tants of a-synuclein associated with familial cases of Par-kinson's ... higher yield of the pure protein. Both proteins were shownto be better than 95% pur e by a lkaline urea P AGE, with only the b-casein showing slight contamination with aglycosylated form of j-casein.Recombinant...
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