Báo cáo y học: "Population genetics of cancer cell clones: possible implications of cancer stem cells" pptx

... potential of genetically heterogeneic tumours. Finally, if we consider a cancer stem cell model where clonal evolution is occurring onlyinasubsetofthecancercells(thestemcells)wecanseethatforanysizeof tumour, ... Biology and Medical Modelling 2010, 7:42 http://www.tbiomed.com/content/7/1/42 Page 2 of 10 RESEARC H Open Access Population genetics of cancer cell clones: possi...

Ngày tải lên: 13/08/2014, 16:20

... species of mercury (methyl- and ethyl-mercury). Idiosyncratic non-allergic toxic reactions to mercury may be independent of the exposure dose [2]. There was no evidence of any other symptoms connected ... removal of the mercury amalgam. Finally, low haemoglobin concentration and low hemat- ocrit were related to anemia, which was possibly pro- voked by the toxic effect of mercury on...

Ngày tải lên: 11/08/2014, 23:21

... leading to pathology may exist prior to cancer initiation. Background Family history and race represent two of the greatest contrib- utors to the probability of developing cancer of the prostate. Recent ... measure of an underlying predisposition to cancer phenotypes reflected by cancer grade: low pathological grade (Gleason ≤6) versus cancers of higher grade (Gleason 7-10)....

Ngày tải lên: 14/08/2014, 07:21

... However, activin A has been recently shown to play a role in the mainte- nance of the pluripotency of human embryonic stem cells [40]. The maintenance of pluripotency of embryonic stem cells could involve Wnt ... recognized by the SH3 antibody, and express prolyl-4-hydroxylase. Prolyl-4-hydroxy- lase was shown to be expressed by synoviocytes [18,24] but to be absent on BM-MSC usin...

Ngày tải lên: 09/08/2014, 07:20

... field study of 3 metabolically- related, polymorphic enzyme loci, with relatively high levels of heterozygosity, in an orchard population of D. melanogaster. The enzymes chosen ... of Drosophila melanogaster. In : H ECHT M., S TEERE W. (ed), Essays in Evolution and Genetics in Hovor of Theodosius Dobzhansky, 381-389, Appleton-Century-Crofts,...

Ngày tải lên: 09/08/2014, 22:23

... genetic variability of 7 fish-farm strains and 14 wild populations of brown trout was studied by electrophoretic analysis of 23 enzyme systems coded for by 52 loci. The total ... may be drawn from our results for the utilisation and management of genetic variability. First, hatchery populations only exhibit 50 p. 100 of the total variabi...

Ngày tải lên: 09/08/2014, 22:23

... - a Genotype called as reference homozygote by sequencing and heterozygote by MassARRAY or heterozygote by sequencing and alternative homozygote by MassARRAY. b Genotype called as heterozygote by sequencing ... homozygote by MassARRAY or alternative homozygote by sequencing and heterozygote by MassARRAY. c Uncalled genotype or tri-allelic in one of the two. Concordant Homozygous alternate v...

Ngày tải lên: 09/08/2014, 22:23

... Effect of isotype antibody on cell migration. IS: isotype antibody; V:VEGF neutralizing antibody; BGC/STC+IS: BGC/STC cell supernatants added with isotype antibody; BGC/STC+V: BGC/STC cell supernatants ... representative of three independent experiments. (E) effect of isotype antibody on cell migration. IS: isotype antibody; V:VEGF neutralizing antibody; BGC/STC+IS: BGC/STC cel...

Ngày tải lên: 10/08/2014, 05:21

... manuscript. Author Details 1 Gastroenterology Division, Yokohama City University School of Medicine, Japan and 2 Department of Pathology, Yokohama City University Hospital, Japan References 1. Iishi ... treatment of the minute cancer and esophageal * Correspondence: inamorim@med.yokohama-cu.ac.jp 1 Gastroenterology Division, Yokohama City University School of Medicine, Japan Fu...

Ngày tải lên: 11/08/2014, 12:20

... 13:993-1018. 33. Peters CS, Malesky LA: Problematic usage among highly-engaged players of massively multiplayer online role playing games. Cyberpsychol Behav 2008, 11:481-484. 34. Yee N: The Demographics, ... Khazaal Y, Rochat L, Gay P, Zullino D, Van der Linden M: Psychological Predictors of Problematic Involvement in Massively Multiplayer Online Role-Playing Games: Illustration in a Sa...

Ngày tải lên: 11/08/2014, 15:22