Báo cáo y học: " Research In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of β-amyloid plaques associated with Alzheimer''''''''s disease" doc
Báo cáo y học: " Research In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of β-amyloid plaques associated with Alzheimer''''s disease" doc
... in the brain increases with age, whereas the activity of AChE declines. BChE may, there- fore, play a more prominent role in ACh hydrolysis in the aging brain. The presence of BChE in the amyloid ... Ul-Haq et al., In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-ben- zothiazepine against BChE in the fo...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "Research in action: using positive deviance to improve quality of health care" ppt
... deviance studies is the linking of the qualitative findings (i.e., hypotheses) and the quantitative measures of those varia- bles hypothesized to influence performance. A benefit of the mixed methods ... trajectory of diffusion, or spread, of innova- tions throughout an industry (Figure 2): features of the innovation, the dissemination strategy, the alignment of t...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: " RESEARCH ARTICLE Open Access One-year risk of psychiatric hospitalization and associated treatment costs in bipolar disorder treated with atypical antipsychotics: a retrospective claims database analysis" doc
... pro- pensity scores were within 0.25 standard deviations of the logit of the propensity score. All analyses were conducted in propensity score-matched cohorts of the study s ample. The primary analysis ... discontinued their index antipsy- chotic during the 1-year follow-up period, and less than 5% completed a full year of follow-up taking their index antipsychotic medicat...
Ngày tải lên: 11/08/2014, 16:22
Báo cáo y học: " Research Upregulation of CD23 (FcεRII) Expression in Human Airway Smooth Muscle Cells (huASMC) in Response to IL-4, GM-CSF, and IL-4/GM-CSF" pot
... airway remodeling [1]. The increase in bronchial smooth muscle, both hypertrophy [2] and hyperplasia [3], plays a critical role in the develop- ment of airway hyperreactivity (AHR), the hallmark of asthma. ... IL-4/GM-CSF inducing increased expression of CD23, both IL-4 and GM-CSF alone independently increased the expression of CD23 in huASMC. The percentage of cells...
Ngày tải lên: 13/08/2014, 13:22
Báo cáo y học: "Research Glucose sensing in the pancreatic beta cell: a computational systems analysis" ppsx
... consistent with the finding of increased glycolytic intermediates and pyruvate after glucose challenge in the INS1 β-cell line [41] as well as the increase in Ψm with increased glucose in mouse ... phosphorylation is the key limiting step for the steady-state rate of glycolysis in β-cells. However, the overall rate of ATP synthesis at high workloads can also be l...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "Research A generalized physiologically-based toxicokinetic modeling system for chemical mixtures containing metal" pdf
... that, depending on the types of metabolic interactions, there is the potential for substantial increases in the steady-state level of benzene in the liver. It must be noted that the precise relationships between ... is inhibited by As III . Urinary excretion of organic and inorganic arsenic is currently the only mechanism for elimina- tion in the model. The GTMM...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "Research Chemotherapy in conjoint aging-tumor systems: some simple models for addressing coupled aging-cancer dynamics" doc
... that the behavior of the system is complex and that the specifications of a chosen drug in terms of the decay and initial value, combined with the specifications of the system in terms of the inter-dependence ... beginning of the therapy. With no treatments, they soon decay to zero. Implementing the drug with a strength of a T (1 - e mu ) = 0.1 mainta...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: " Research Transperineal prostate biopsy: analysis of a uniform core sampling pattern that yields data on tumor volume limits in negative biopsies" pdf
... efficiency. Assume the initial biopsy cores, which were placed evenly on one side of the midline, are negative (no tumor detected). One then places all the rebiopsy cores evenly on the other side of the ... math- ematical analysis of the transperineal technique relies on a model of the biopsy cores and a model of the tumor. The biopsy core model employs a grid patt...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "he Association Among Lipoprotein-associated Phospholipase A2 Levels, Total Antioxidant Capacity and Arousal in Male Patients with OSA"
... Capacity Total antioxidant capacity in patients was de- termined with Antioxidant Assay Kit (Cayman Chemical Company, USA). The assay relies on the ability of antioxidants in the sample to inhibit ... sample to inhibit the ox- idation of ABTS ® (2,2'-azino-di-[3-ethylbenzthiazoline sulphonate]) to ABTS ® · + by methmyoglobin. The capacity of the antioxidant...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... of cytosine (C) by thymine (T) at nucleotide 677 of the MTHFR gene that converts an alanine to a valine residue was responsible for the thermolability of MTHFR. Actually, the frequency of the ... Frequency of the MTHFR genotypes and the result of the Chi square testing in the different studied groups. Showing the frequency and the results of the cross...
Ngày tải lên: 03/11/2012, 09:49