Báo cáo y học: " Research Mathematical framework for human SLE Nephritis: disease dynamics and urine biomarkers" pdf

... al., Mathematical framework for human SLE Nephritis: disease dynamics and urine biomarkers Theoretical Biology and Medical Modelling 2010, 7:14 Budu-Grajdeanu et al. Theoretical Biology and Medical ... 7:14 http://www.tbiomed.com/content/7/1/14 Open Access RESEARCH Research Mathematical framework for human SLE Nephritis: disease dynamics and urine...

Ngày tải lên: 13/08/2014, 16:20

... and collected the results for analysis. GY, MK and TL developed methodology for in silico analysis of the results and GY analyzed the results. MG did the MLPA validation of the not previously ... term. More specifically, in the absence of copy number variation, is 2.0 for an AA genotype, for an AB genotype, and 0 for a BB genotype. The fitting procedure yields estimates fo...

Ngày tải lên: 09/08/2014, 20:20

... contributions CC and MG conceived and designed the study. CC and KKY performed the full analysis. CC, KKY, KYY, RA, JR, CS and MG wrote the manuscript. Received: 21 December 2010 Revised: 26 January 2011 Accepted: ... a variety of species ranging from yeast to human. More specifically, we show that chro- matin features can accurately predict t he expression levels of genes and coll...

Ngày tải lên: 09/08/2014, 22:23

... Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Ave, New Haven, CT 06511, USA. 5 Department of Genetics, Stanford University School of Medicine, Alway M344, Stanford, CA 94305, USA. 6 Program ... Biology and Bioinformatics, Yale University, 266 Whitney Ave, New Haven, CT 06511, USA. Authors’ contributions TG designed the experiments and completed the analysis. AA an...

Ngày tải lên: 09/08/2014, 22:24

... mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis Evgeniya A Oshchepkova-Nedosekina* and Vitalii A Likhoshvai Address: Institute of Cytology and Genetics ... the active site of a conformationally dynamic enzyme by directed mutation. Role of dynamics in structure- function correlations in Escherichia coli adenylosuccinate synthetase. J B...

Ngày tải lên: 13/08/2014, 16:21

... not for citation purposes) Theoretical Biology and Medical Modelling Open Access Research A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as ... determined in prelim- inary cytotoxicity assays: 5 mM 3-AB, 100 µM NU1025 and 3 µM PJ34. Clonogenic survival assay Clonogenic survival assays were carried out using the flow cytometric c...

Ngày tải lên: 13/08/2014, 16:21

... 17 (page number not for citation purposes) Theoretical Biology and Medical Modelling Open Access Research A mathematical model for LH release in response to continuous and pulsatile exposure ... (GnRH) is released by the hypothalamus in a pulsatile fashion and stimulates luteinizing hormone (LH) and follicle stimulating hor- mone (FSH) release by pituitary cells by a complex...

Ngày tải lên: 13/08/2014, 22:22

... binding profiles is widely used for such pur- poses [9], yet provides merely a fraction of the information necessary to support the research community. An excellent and extensive comparison of ... laboratory will maintain PAZAR for the long-term as it is necessary for our on-going research, ideally the project would expand through the engagement of a cooperative research communit...

Ngày tải lên: 14/08/2014, 08:20

... the one hand, an alternative human com- puter interaction technique for activities where hands can barely be employed and, on the other, a solution for dis- abled people who maintain eye movement ... used a system composed of three cameras and two sources of differently polarized light. Yoo and Chung [10] employ five infrared lights and two cameras. Shih and Liu [11] use two came...

Ngày tải lên: 22/06/2014, 19:20

... Nakayama EE, Yokoyama M, Sato H, Levy JA, Shioda T: A single amino acid of the human immunodeficiency virus type 2 capsid affects its replication in the presence of cynomolgus monkey and human TRIM5alphas. ... virological analyses in vitro. MY and HS performed structure modeling analyses. HY and MK examined viral genome sequences. NI and TM analyzed the data and wrote the paper....

Ngày tải lên: 13/08/2014, 01:20