Báo cáo y học: " A mechanistic model of infection: why duration and intensity of contacts should be included in models of disease spread" ppt
Báo cáo y học: " A mechanistic model of infection: why duration and intensity of contacts should be included in models of disease spread" ppt
... Access Research A mechanistic model of infection: why duration and intensity of contacts should be included in models of disease spread Timo Smieszek Address: Institute for Environmental Decisions, Natural ... The average dose of infectious material that is ingested by an individual is a linear function of the duration and intensity of the con...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice" pps
... general suppression of activity of inflam- matory cells and relaxation of airway and vascular smooth muscle [17]. Levels of intracellular cAMP are determined by the enzymatic balance between synthesis ... potent and broader anti-inflammatory effects against smoke-induced lung inflammation than roflumilast. Moreover, the protective effect of PDE4B/4D and 7A AON was maintaine...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "A dynamic model of gene expression in monocytes reveals differences in immediate/early response genes between adult and neonatal cells" potx
... performed in Matlab R14 (Nat- ick, MA) and Statistica v7 (Tulsa, OK, USA). An alpha level of 0.05 was considered statistically significant for all anal- yses. Analysis of the apoptosis assays was undertaken ... [25]. DFA analysis of phases of monocyte activation comparing cord and adult cellsFigure 4 DFA analysis of phases of monocyte activation comparing cord and adult ce...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: " A predictive model for respiratory syncytial virus (RSV) hospitalisation of premature infants born at 33–35 weeks of gestational age, based on data from the Spanish FLIP study" pdf
... Spain. Finally, since day care attendance is not commonly practised in Spain, there were limited data on this variable and it was not included in the final analyses. External validation of the model ... improve standards of care by better identifying high risk infants and, thus, optimising prophylaxis. It may also be used to inform guidance and to help clarify the justifi-...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "A mathematical model of quorum sensing regulated EPS production in biofilm communities" pptx
... upregulated, initiatin g positive feedback, and the bacteria subse- quently produce AHL molecules at an increased rate. As a number of traits in bacterial biofilms relevant for human and plant health are ... depth of a growing biofilm. Bulletin of Mathematical Biology 2003, 65(6):1053-1079. 36. Janakiraman V, Englert D, Jayaraman A, Baskaran H: Modeling growth and quorum se...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: " A computational model for functional mapping of genes that regulate intra-cellular circadian rhythms" pps
... significant advantages of functional map- ping is that it can ask and address biologically meaningful questions about the interplay between gene actions and trait dynamics by formulating a series of ... rhythms. Typically, biological rhythms are dynamic traits, and the pattern of their genetic determination can change dramat- ically with time. In this article, we have incorpor...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: " A mathematical model of venous neointimal hyperplasia formation" doc
... be (expanded and) used by clinical researchers as a testbed for exploring and evaluating various therapies that can tar- get both the traditional and the alternative pathways that are involved in the pathogenesis ... and fibroblasts of the vas- cular media and adventitia, with migration into the intima and proliferation. In addition, there is a significant adventitial a...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: " A statistical model for the identification of genes governing the incidence of cancer with age" pptx
... 8 0 2 4 6 8 10 12 Time Number of clones AA actual AA fitted Aa actual Aa fitted aa actual aa fitted 1 2 3 4 5 6 7 8 0 2 4 6 8 10 12 Time Number of clones AA actual AA fitted Aa actual Aa fitted aa actual aa fitted BioMed ... 8 1 2 3 4 5 6 7 8 Time Number of clones AA actual AA fitted Aa actual Aa fitted aa actual aa fitted 1 2 3 4 5 6 7 8 1 2 3 4 5 6 7 8 Time Number of clones AA actua...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: " A mathematical model of glutathione metabolism" pps
... glutathione have been implicated in aging and a host of diseases including Alzheimer's disease, Parkinson's disease, cardiovascular disease, cancer, Down syndrome and autism. Approach: We explore ... DNA-methyl- transferase; FTD: 10-formyltetrahydrofolate dehydroge- nase; FTS: 10-formyltetrahydrofolate synthase; GCS: γ- glutamylcysteine synthetase; GDC: glycine decarbox...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "A novel model of common Toll-like receptor 4- and injury-induced transcriptional themes in human leukocytes" pot
... 05 and ≥1.2-fold change from base- line. Data were also exported for ana lysis by Ingenuity Pathway Analysis ™ (Ingenuity, Palo Alto, CA, USA) as previously described [3]. qPCR Where indicated, ... systemic inflammation and injury. Introduction Circulating leukocytes play a central role in host immu- nity, and are a major source of inflammatory mediators released in response t...
Ngày tải lên: 13/08/2014, 21:21