... and Xa. Bioorg Med Chem Lett 2004,21:5263-5267.34. Sato M, Motomura T, Aramaki H, Matsuda T, Yamashita M, Ito Y, Kawakami H, Matsuzaki Y, Watanabe W, Yamataka K, Ikeda S,Kodama E, Matsuoka M, ... display sim-ilar 3D folding of the catalytic domain and a conservedcatalytic triad of metal-coordinating carboxylates. INcatalyses at least two reactions: 1) 3' processing, and 2)strand ... belongs to a family of polynucleotidyl transferases/esterases, comprising transposases, RNAses H, and the Argonaut RNAse associated with Dicer (involved in the gene-silencing pathway) [1,6]. These...