Báo cáo y học: "Frequent activation of EGFR in advanced chordomas" pptx

... Research Paper The characterisation of mucin in a mature ovarian teratoma occurring in an eight year old patient Anwar Suleman Mall 1 , Marilyn Tyler 1 , Zoe Lotz 1 , Alan Davidson 1 , Jerry Rodrigues ... presence of MUC5AC (M1 antigen) and MUC6 have previously been found in ovarian muci- nous cyst. We characterized the mucins in the crude mucus an...

Ngày tải lên: 26/10/2012, 10:03

... 2001;413(6853):316-22. 4. Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, Imaki H, Ishida N, Okumura F, Nakayama K, Nakayama KI. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box ... Tsunematsu R, Nakayama K, Oike Y, Nishiyama M, Ishida N, Hatakeyama S, Bessho Y, Kageyama R, Suda T, Nakayama KI. Mouse Fbw7/Sel-10/Cdc4 is required for notch degradati...

Ngày tải lên: 31/10/2012, 16:49

... receiving combination therapy. Hepatology 2004;40:1450-8. 15. Crippin JS, McCashland T, Terrault N, Sheiner P, Charlton MR. A pilot study of the tolerability and efficacy of antiviral therapy in ... costly and has not been studied rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are now widely used...

Ngày tải lên: 31/10/2012, 17:11

... transfection of mutant recep- tors of the human and mouse PXR ligand binding domains. By modeling the human PXR ligand binding domain we have identified and mutated two polar residues in the puta- tive ligand ... both adjacent to the ligand binding pocket. The crystal structure of human PXR has shown that these residues are also involved in hyd...

Ngày tải lên: 08/03/2014, 16:20

... (Eur. J. Biochem. 269) 1013 Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types Mo ´ nica Yunta 1 , Jose ´ L. Oliva 2 , ... studied the possibility that activation of the N-terminal Jun k inase (JNK) activity might be a component of the cellular respo...

Ngày tải lên: 08/03/2014, 22:20

... 2002 The role of zinc in the methylation of the coenzyme M thiol group in methanol :coenzyme M methyltransferase from Methanosarcina barkeri New insights from X-ray absorption spectroscopy Markus ... presence of coen- zyme M, indicate how zinc interacts with its substrate coenzyme M and how zinc is most probably coordinated in...

Ngày tải lên: 17/03/2014, 23:20

... T. Sumimoto (Eur. J. Biochem. 269) Ó FEBS 2002 Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu ... Structural and functional analysis of the riboflavin synthesis genes encoding GTP cyclohydrolase II (ribA), DHBP synthase (ribBA), r...

Ngày tải lên: 31/03/2014, 08:20

... purposes) c) The role of probiotics in Allergic Rhinitis Reports on the efficacy of probiotics in treating allergic rhinitis are conflicting. Some studies suggest efficacy such as the study by Wang and ... allergy. factors influencing development of the microbiota. Ann Med 1999, 31(4):288-92. 15. Kalliomaki M, Isolauri E: Role of intestinal flora in the develop- ment...

Ngày tải lên: 08/08/2014, 21:20

... morphogenetic protein (BMP) ligands in synovium and cartilage during collagen-induced arthritisQuantitative polymerase chain reaction of different bone morphogenetic protein (BMP) ligands in synovium and ... are increasingly used to address the role of BMPs in disease pathogenesis. Our group previously studied the role of BMP signaling in joint homeostas...

Ngày tải lên: 09/08/2014, 13:22

... how the deficiency in catalase activity affected the lung inflam- mation induced by bleomycin. In BAL fluid, total numbers of inflammatory cells were increased after bleomycin administration in ... 11:183 http://respiratory-research.com/content/11/1/183 Page 2 of 13 inflammation in acatalasemic mice after bleomycin administration. In bleomycin-induced lung injury animal m...

Ngày tải lên: 12/08/2014, 13:22

... RESEARC H ARTIC L E Open Access Frequent coexistence of anti-topoisomerase I and anti-U1RNP autoantibodies in African American patients associated with mild skin involvement: a retrospective clinical ... was obtained from all patients accord- ing to the Declaration of Helsinki. Autoantibody analysis Autoantibodies in sera from the initial visit o...

Ngày tải lên: 12/08/2014, 15:23

... not necessarily reflect those of his employer, the National Institutes of Health (NIH). Work in KTJ’s laboratory is supported in part by intramural funding from the National Institute of Allergy and Infectious ... J, Qu S, Yu X, Meng Z, He X, Jiang S, Shao Y: Phenotypic and genotypic characterization of human immunodeficiency virus type 1 CRF07_BC strains circulating in th...

Ngày tải lên: 13/08/2014, 01:20

... transcript is located to the left of the retroviral tag on the chromosome, the notation for the gene precedes the notation for the tag (G ± T ). If the transcript is to the right of the retroviral ... also of the mature species of the mir- 106a cluster. This, in turn, suggests that the miRNA cluster can drive the development of T lymphomas. Al...

Ngày tải lên: 13/08/2014, 09:20

... finding suggests that CD30L is not involved in the constitutive NF-κB acti- vation in TL-OmI cells. Expression of CD30 in primary ATL cells Next, we examined CD30 expression in primary ATL cells by ... binding protein pathways. Virus Genes 2001, 22:279-287. 19. Akagi T, Ono H, Shimotohno K: Expression of cell- cycle regula- tory genes in HTLV-I infected T -cell...

Ngày tải lên: 13/08/2014, 09:21

... USA). Receptor tyrosine kinases (RTK) activation profiling using antibody arrays The activation of RTK and their downstream signaling pathways were analyzed using the Proteome Profiler™ Array kits (ARY001 ... [16]. In our study, we found significant activation of EGFR, HER2 and HER4 in respectively 12, one a nd one out of 12 cases, using the same antibody arrays. Interesting...

Ngày tải lên: 13/08/2014, 15:21