Báo cáo y học: " Harmonization of monographic standards is needed to ensure the quality of Chinese medicinal materials" docx

... and globalization of Chinese medicine. A harmonized regulatory system would improve the quality of CMMs thereby ensuring the safety of the products and assisting Chinese medicine practitioners in their practice. ... Access Commentary Harmonization of monographic standards is needed to ensure the quality of Chinese medicinal materials Kelvin Chan* 1...

Ngày tải lên: 13/08/2014, 15:21

... experiments related to the activity of wild type Rev, the negative con- trol and to the relative amount of cell lysates in the sam- ples. As expected, M4 displayed very low activity compared to the wild type ... study, the M4 mutant was studied to clarifying why oligomer formation is essential for Rev activity by assessing the requirements for restora- tion of t...

Ngày tải lên: 13/08/2014, 09:21

... of the molecular mechanisms of action of this polymorphism. Because these results were based on the low frequency of A/A , they might be inconsistent due to the random errors. Studies of a ... with the risk of Helicobactor pylori infection and gastric atrophy Yasuyuki Goto 1 , Takafumi Ando 2 , Kazuko Nishio 1 , Sayo Kawai 1 , Yoshiko Ishida 1 , Mariko Naito 1...

Ngày tải lên: 31/10/2012, 15:37

... m M sorbitol, the protein is mostly present as the b form, but this form is now bound to eIF4E. The main effect of the higher concentrations of sorbitol is to cause the loss of the most phosphorylated c-form, ... leading to a loss of cell viability. In view of this substantial inhibition of protein synthesis, it will be important to consider their effects...

Ngày tải lên: 18/03/2014, 01:20

... because they s how structural similarity to the human brain endomorphins (e.g. YPWG-NH 2 ) [23]. The sequences of two tryptophyllins are as follows: tryptophyllin L1, FPWL-NH 2 ; tryptophyllin L2, ... into the gut) when the animal is stressed, sick, or under attack. Logically, there are two possibilities, either the nNOS inhibitor is playing some regulatory role in the ani...

Ngày tải lên: 31/03/2014, 15:20

... [30]. Synthesis of the inflammatory cytokines IL-1 and TNF-α and expression of their receptors are enhanced in OA [29–31]. Both cytokines have been shown to potently induce degrada- tion of cartilage ... [29,31]. The activity of many MMPs increases in OA by either an increase in their own synthesis, an increased activation by their proen- zymes, or decreased activity of their...

Ngày tải lên: 09/08/2014, 01:21

... allowing them to understand the decision-making process leading to the use of the specific therapy remains daunting. The issue of the relative risk for a therapeutic in the context of its relative benefit ... twenty-first century there is still the implied contract with the physician that they are able to determine the appropriate and safe therapy for a patient...

Ngày tải lên: 09/08/2014, 07:20

... changed the way we view rheumatoid arthritis Joint failure is the final common pathway of an array of inflammatory, crystal, and degenerative arthritis. The advan- tage of seeing patients early in the ... oedema to be a much stronger predictor of erosion than synovitis [20,45,46]. We propose that bone oedema is secondary to synovitis and consistent with this hypothesis...

Ngày tải lên: 09/08/2014, 13:22

... Ni_jian2008@163.com 1 Department of Hematology and Oncology, Children’s Hospital of Soochow University, Suzhou, China Full list of author information is available at the end of the article Jian et al. Journal of Hematology ... PE- conjugated CD11b antibody or PE-conjugated IgG1iso- type control antibody at 4°C for 30 min and analyzed by flow cytometry using a FACScan flow cyto...

Ngày tải lên: 10/08/2014, 21:23

... benefit of composite indicators of quality is that they are communicable to diverse stakeholders and may be leveraged to induce competition on quality. Payers of healthcare increasingly employ these ... Saltelli A, Tarantola S: Uncertainty and sensitivity analysis techniques as tools for the quality assessment of composite indicators. Journal of the Royal Statistical...

Ngày tải lên: 11/08/2014, 05:21