Báo cáo y học: "Harmine activates intrinsic and extrinsic pa

Báo cáo y học: "Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanom" doc

... which indi- cated the involvement of harmine in both intrinsic and extrinsic pathways of apoptosis. Cell death mechanism induced by the harmine in B16F-10 melanoma cells may be mediated by the ... inhibitory effects of harmine on some transcription factors and proinflammatory cytokines that protect cell from apoptosis. Conclusion: Harmine activates both intrinsic...

Ngày tải lên : 13/08/2014, 14:20

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Báo cáo y học: " Physical health behaviours and health locus of control in people with schizophrenia-spectrum disorder and bipolar disorder: a cross-sectional comparative study with people with nonpsychotic mental illness" ppt

... this study was of a preliminary nat- ure set against the prospect of addressing more tightly focused research questions in the near future, guided by the findings of the present study. Clinical ... widely recognised method utilised in research involving self-rat- ing of health [28]. Secondly, we asked participants to estimate their ten-year risk of suffering myocardial infarctio...

Ngày tải lên : 11/08/2014, 15:22

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Báo cáo y học: "Global nucleosome distribution and the regulation of transcription in yeas" doc

... with only intergenic DNA in order to determine histone occupancy in intergenic regions. Although it should be kept in mind that the degree of histone cross-linking may not always accurately reflect ... results in differential segregation of intergenic regions of the genome into the aqueous phase. Nagy et al. [13] proposed that this may be a result of different efficiency of...

Ngày tải lên : 14/08/2014, 14:21

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Báo cáo y học: "Lifetime health effects and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach"

... using original length of stay data and 2003 nursing day prices. Subsequently, total individual costs of care during the first six months were computed by holding the original ratio between inpatient ... by a multidisciplinary team [33]. However, length of stay in stroke units may vary within Europe and this may change the financial, short-term, impact of stroke services outsid...

Ngày tải lên : 25/10/2012, 10:35

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Báo cáo y học: "HLA-DR regulation and the influence of GM-CSF on transcription, surface expression and shedding

... percentage of cells expressing HLA- DR on monocytes and the density of HLA-DR was measured. Immuno-fluorescent microscopy of HLA-DR in PBMC Cytospins of PBMC obtained from healthy controls and septic ... mechanism involved in the regulation of HLA-DR, as described in the study of Fumeaux et al. (2002), flow cytometry and immunoflourescence were used to determine in...

Ngày tải lên : 03/11/2012, 09:57

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Báo cáo Y học: A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H37Rv and the secreted chorismate mutase (y2828) from Yersinia pestis pptx

... Yersinia pestis (*YpCM, y2 828), puriﬁcation of the protein, investigation of the properties of the enzyme, and the crystal structure analysis of the protein. Results and Discussion Annotation of CMs in M. ... cleavage by subtilisin between the prodomain and the target protein, thus releasing the target protein in its native form, begin- ning with the initiator methionine...

Ngày tải lên : 17/03/2014, 17:20

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Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot

... dynamics. Introduction of conformational restraint through cycliza- tion has become a standard strategy in medicinal chemistry for increasing the receptor afﬁnity and selectivity of peptide ligands ... concentrations and polyphosphoinositide turnover in cultured rat astrocytes. MATERIALS AND METHODS Materials All amino-acid residues, preloaded 4-hydroxymethyl- phenoxymethyl-copo...

Ngày tải lên : 24/03/2014, 04:21

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Báo cáo Y học: Azidothymidine causes functional and structural destruction of mitochondria, glutathione deﬁciency and HIV-1 promoter sensitization pptx

... is abundantly expressed in eukaryotic cells, and plays an important role in regulation of cellular redox potential by eliminating ROS including H 2 O 2 . Intracellular concentration of this molecule ... More importantly, AZT treatment is thought to be an unexpected cause of the oxidative stress-induced HIV-1 activation [10,11]. GSH, a cysteine-containing tripeptide (c-glutamyl- cy...

Ngày tải lên : 24/03/2014, 04:21

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Báo cáo y học: "On demand treatment and home therapy of hereditary angioedema in Germany - the Frankfurt experience" pptx

... in hereditary angioedema (HAE) is characterized by interindividual and intraindividual variability in symptom expression over time. Flexible therapy options are needed. Methods: We describe and ... gastrointestinal tract, and the throat, the latter leading to potentially life-threat ening laryngeal edema. Manifestation of acute edema in hereditary angioedema is characterized by...

Ngày tải lên : 08/08/2014, 21:20

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Báo cáo y học: "VLA-4-dependent and -independent pathways in cell contactinduced proinflammatory cytokine production by synovial nurselike cells from rheumatoid arthritis patients" potx

... by chronic infiltration of T lymphocytes and B lymphocytes, plasma cells, and macrophages into the synovial tissue of joints [13,14]. High levels of proinflammatory cytokines are invariably ... cells, and show that lymphocyte binding mediated by the very late antigen-4 (VLA-4)-independent pathway is sufficient to induce the accelerated proinflammatory cytokine production. Materi...

Ngày tải lên : 09/08/2014, 06:22

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