Báo cáo y học: "Enhancement of in vitro interleukin-2 production in normal subjects following a single spinal manipulative treatment" potx
Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"
... components by use of the inverse Diels Alder technology. The high chemical stability and the ease of synthesis qualify these polyamide building blocks as favourites for intracellular delivery and ... SScciieenncceess 2011; 8(5):387-396 Research Paper Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers Ruediger Pipkorn1 * , Manfred ... Solid phase synthesis of the Reppe Anhy-dride polyamide pentamer I. To demonstrate the high efficiency of the DARinv-based Click -chemistry, we synthesized a pentamer which is amide-based...
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Báo cáo y học: "Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes"
... Effects of p-Synephrine alone and in Combination with Selected Bioflavo-noids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes Sidney J. Stohs1, Harry G Preuss2, ... weight control agent. Key words: p-Synephrine, naringin, hesperidin, resting metabolic rate, heart rate, blood pressure Introduction The bioflavonoids hesperetin and naringenin are widely distributed ... particularly in caffeine-sensitive individuals [39]. The absence of changes in blood pressure, rest-ing heart- rate and self-ratings in the four treatment groups involving p-synephrine, naringin and...
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Báo cáo y học: "Characterization of erythrovirus B19 genomes isolated in liver tissues from patients with fulminant hepatitis and biliary atresia who underwent liver transplantation"
... Characterization of erythrovirus B19 genomes isolated in liver tissues from patients with fulminant hepatitis and biliary atresia who underwent liver transplantation Kenji Abe 1, Tetsuya Kiuchi ... words: Erythrovirus B19; erythrovirus B19 genome; fulminant hepatitis; biliary atresia; liver transplantation 1. Introduction Erythrovirus (formally parvovirus) B19 (B19) causes a wide range of ... patients with fulminant hepa-titis and biliary atresia. Interestingly, all fulminant hepatitis patients infected with B19 had the replicative form of B19 mRNA. It is noteworthy that serum B19 DNA...
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Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... Discussion and Conclusions To address the question whether the +T294C polymorphism in PPAR is associated with the risk for coronary heart disease and/ or plasma lipid levels in women, we investigated ... state the activities of numerous interacting genes are altered which may influence the effect of PPAR on metabolism. In our data and in the study by Skogsberg et al., the effect of the C ... software. The association between the +294T/C polymorphism and serum lipids, coronary heart disease, and body mass index (BMI) was calculated using the Student’s t-test analysis with genotype as the...
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Tài liệu Báo cáo Y học: Prediction of protein–protein interaction sites in heterocomplexes with neural networks ppt
... determined by its p osition in t heÓ FEBS 2002 Predicting protein–protein interaction sites (Eur. J. Biochem. 269) 1357 Prediction of protein–protein interaction sites in heterocomplexes with neural ... recently, methods were devised for predictingresidues involved in protein interaction s ites in the absence of any structural reports. By analysing hydrophobicitydistribution, linear stretches of ... mutations, by solving the structure of some of thecomplexes or by other experimental means.CONCLUSIONSWe have analysed the possibility of predicting the residuesforming part of protein–protein interacting...
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Tài liệu Báo cáo Y học: Induction of (2¢)5¢)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide docx
... Induction of (2Â)5Â)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide Vladislav A. ... to24 h . The i dentity of the p3A2product synthesized by the (2–5)A synthetase both in tissue and in primmorphs of S. domuncula was verified by TLC and HPLC analysis astriphosphorylated and/ or ... activated by certain classes of RNA, mainly double-stranded RNA [14]. In vertebrates the (2–5)A pathway is also induced by interferons [15]. The major enzyme in this pathway, the (2–5)A synthetase...
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Tài liệu Báo cáo Y học: Analyses of the CYP11B gene family in the guinea pig suggest the existence of a primordial CYP11B gene with aldosterone synthase activity docx
... decrease in the activity for the 11b-hydroxylase, CYP11B1 . Intriguingly, however, the 11b-hydroxylase activity of the aldosterone synthase CYP11B2 was basically unaffected whereas the 18-hydroxy-lation ... frame.Thus, the guinea pig presumably branched off at a very earlytime point within the mammalian radiation irrespective of the branching order. Intriguingly, however, the guinea pig possesses already ... 18-oxidation activity of CYP11B2 using varioussubstrates thus showing it to be the aldosterone synthase of the guinea pig. It was interesting to note that CYP11B2 of the guinea pig had a considerably...
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Báo cáo Y học: Formation of aberrant phosphotau fibrillar polymers in neural cultured cells doc
... methods). Bar indic ates 200 nm.Ó FEBS 2002 Tau aggregates in cultured cells (Eur. J. Biochem. 269) 1487 Formation of aberrant phosphotau fibrillar polymers in neural cultured cells Mar Pe´rez1,Fe´lix ... protein [3,4] that in pathologicalsituations, and in a hyperphosphorylated form [5–8]assembles into fibrillar polymers. The mechanism for that aberrant tau assembly has been widely analyzed by ... University, Cleveland, OH, USAHere we show, for the first time, the in vitro formation of filamentous aggregates of phosphorylated tau protein in SH-SY 5Y human neuroblastoma cells. The formation of such...
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Báo cáo khoa học: Initiation of JC virus DNA replication in vitro by human and mouse DNA polymerase a-primase ppt
... replication of aplasmid carrying the JCV origin. Columns 2 and 3, SV40 Tag with human and murine DNA polymerase a-primase, respectively; columns4 and 5, JCV Tag with human and murine DNA polymerase ... driven by murine comparedwith human DNA polymerase a-primase. In order toFig. 1. DNA replication assays in murine FM3A cell extracts depleted of DNA polymerase a-primase using the SV40 (A) and JCV ... origin (A); the JCV system con-tains JCV TAg and DNA with the JCV rep-lication origin (B). DNA polymerase (0.25 and 0.5 U) of the indicated DNA polymerase a-primase complexes were added (H4, human, columns...
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Báo cáo Y học: Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells potx
... for Zn-induced apoptosis in human Burkittlymphoma B cells. An increase in labile Zn in the cytoplasmmay suppress apoptosis by inhibition of the action of caspase, cytoplasmic apoptosis inducer, ... [53,54]. Caspases, a family of cysteineproteases, play a pivotal role in the execution of apoptosis [26]. We therefore examined the involvement of caspases in the apoptosis induced by Py/Zn. PARP ... substrate of caspases, and proteolysis of PARP is an index of activation of caspases [55–58]. Therefore, we first examined changes in the time courses of induction of apoptosis (Fig. 3A) and proteolysis...
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báo cáo hóa học: " Effects of collagen membranes enriched with in vitro-differentiated N1E-115 cells on rat sciatic nerve " doc
... al.: Effects of collagen membranes enriched with in vitro-differentiated N1E-115 cells on rat sciatic nerve regeneration after end-to-end repair. Journal of NeuroEngineering andRehabilitation ... particular type of nerve tissue engineering approach has very limited effects on nerve regeneration after sciatic end-to-end nerve reconstruction in the rat. Background Nerve regeneration is a complex ... regeneration. In the present study, we aimed at investigating the effects of enwrapping the site of end-to-end rat sciatic nerve repair with equine type III collagen nerve mem-branes either alone...
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Báo cáo y học: "Cost of mental and behavioural disorders in Kenya" ppt
... comparativeterms, the Kenyan estimate of 10% of the Ministry of Health budget is lower than that of the Netherlands and Table 1: Annual cost of operating and organizing psychiatric services in Kenya (1 US$ ... those borne by the health care system and thefamily in directly addressing the problem of MBD; and (b) the indirect costs, i.e. loss of productivitycaused by MBD, which is borne by the individual, ... (food and gas), and utilities accounted for 61%, 5%, 7% and 3%respectively.Table 2 presents a summary of the direct and indirectcosts. The cost of operating and organizing inpatient psy-chiatric...
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Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt
... pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studiesCarlotta ... SSc-related ILD, weexamined the benefit of CYC on lung function as measured by pulmonary function tests by conducting a systematic review and meta-analysis of randomized clinical trials and prospective observational ... dataacquisition and analysis, and in manuscript preparation. PJEparticipated in data acquisition and in manuscript preparation.All authors read and approved the final manuscript.Additional...
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Báo cáo y học: "Activation of monocytes and cytokine production in patients with peripheral atherosclerosis obliterans" docx
... 8:23http://www.journal-inflammation.com/content/8/1/23Page 7 of 7 Plasma levels of pro and anti-inflammatory cytokinesPlasma levels of IL-6, TNF-a and IFN-g were significantlyhigher in patients; t he levels of the anti-infl ammatorycytokines IL-10 ... expression of adhesion molecules of the endothelium and synthesis of other pro-inflammatorycytokines such as IL-1 and IL-6.Similar to results regarding pro-inflammatory cytokines,high levels of anti-inflammatory ... 8:23http://www.journal-inflammation.com/content/8/1/23Page 6 of 7 in peripheral blood, t he objectives of the present studywere to evaluate the plasma levels of anti-inflammatory and inflammatory cytokines including interleukin-6 (IL-6),...
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Báo cáo y học: "Enhancement of in vitro interleukin-2 production in normal subjects following a single spinal manipulative treatment" potx
... previouslydemonstrated that a single spinal manipulative treatment (SMT) accompanied by audible release has an inhibitoryeffect on the production of proinflammatory cytokines in asymptomatic subjects. ... which a complete set of data was available wereincluded in the final analysis. Routine flow cytometry(FACS) examination of cell surface markers ascertainedthat the numbers of IL-2 producing lymphocytes ... manipulation of the lumbar spine and zygapophyseal joint gapping hasbeen demonstrated by use of magnetic resonance imaging in normal subjects [34]. However, a relationship betweenjoint gapping and...
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