Báo cáo y học: "Novel concepts in virally induced asthma" potx

... signaling complex, interferon (IFN)-α (IFNA5) which is a type I IFN involved in early cytokine responses to viral infection, inducible nitric oxide synthase (NOS2A), and the high affinity IgE ... disease in infancy, and perhaps asthma inception, include those that are involved in cytokine production (IFNA13, IL15, IL10, and IL17) and cytokine receptor sig- naling (IL4R,IL9R, and STAT1)....

Ngày tải lên: 13/08/2014, 13:22

... lamivudine resistance. Induction of isoleucine or valine in the YMDD motif results in a sterical hindrance, preventing lamivudine from appropriately configuring into the nucleotide bind- ing site ... virus variants with mutations in the YMDD motif, namely a substitution of methionine to valine (YVDD) and methionine to lysine (YKDD) at position rt204 were present in patients' seru...

Ngày tải lên: 12/08/2014, 04:20

... [9]. Importantly, the utility (and basic scientific understanding) of many of these novel biomarkers has been reinforced by predictable changes in their levels upon specific, clinically relevant ... population clinical research in critical care medicine and the dangers of extrapolating population- centred, relatively uncomplicated, limited, single-organ patho- physiology to the critically...

Ngày tải lên: 13/08/2014, 08:20

... composition is altered, with a de- crease in the fractional content of phosphatidylglycerol and an increase in that of phosphatidylinositol and sphingomy- elin. In addition, the concentration of large ... subsequently se- creted in an organized tubular myelin form, which exists in the alveolar lining fluid subphase. It is from tubular myelin that the surfactant film is formed. Surfa...

Ngày tải lên: 12/08/2014, 18:20

... workplace, a research laboratory that studies fish biology. On a recent holiday, her symptoms completely resolved, but they recurred within a week of her returning to work. The patient later ... of breath and skin rash when feeding the fish. The patient keeps no pets at home, and although there is no personal history of atopy, her father has hay fever. The physical exam- ination was unremarka...

Ngày tải lên: 08/08/2014, 20:23

... quantified superoxide and hydroxyl rad- ical-scavenging effect by electron spin resonance spec- trometry [41]. They reported that in a hypoxanthine- xanthine system, baicalein strongly reduced superoxide radicals. ... kaolin intake induced by ritonavir in rats. Increased kaolin intake induced by ritonavir (mg/kg) was decreased with SbE pretreatment in a dose-related manner (P <...

Ngày tải lên: 10/08/2014, 05:20

... phosphatases play relevant roles in the biology of the yeast (cell integrity, cell c ycle regulation, cation homeostasis, etc) and that they interact with several key signalling pathways. In some cases, ... rcelona, Spain. E-mail: Joaquin.Arino@uab.es Abbreviations: MAP kinase, mitogen activated protein kinase; TOR, target of rapamycin; PP1, type 1 protein phosphatase; PP2A, type 2A prote...

Ngày tải lên: 17/03/2014, 23:20

... locus previously identified in a multiplex family study [2]. UBASH3B and UBAC2 encode ubiquitin-associated proteins. The ubiquitin system is best described in targeting misfolded or damaged proteins for ... easy for a rare condition such as BD. The authors addressed this point by performing the initial analysis on pooled samples and then, having identified potential SNPs, validating the f...

Ngày tải lên: 09/08/2014, 14:22

... for storage [40] 7 Zinc metalloproteinase 28-46 Zinc metalloproteinase- disintegrin (snake) Inflammation; myonecrosis [28,37] 7 Latrotoxin-like (ankyrin repeat domains) 25-33 Alpha-latrotoxin (spider) Pain [45] 6 ... (Cysteine rich secretory protein) 33-68 Helothermine (lizard); cysteine-rich venom protein (snake) Muscle wasting; smooth muscle relaxation [46,47] 1 Sea anemone cytolytic toxin-...

Ngày tải lên: 09/08/2014, 22:23

... maintained using a circulat- ing-water heating pad. An elliptical skin incision was made around the left forelimb girdle, encompassing the axillary fold medially in anticipation of primary skin ... all stained myelinated fibers were included in the database for analysis. In order to prevent grading bias, the observe r was blinded to the origin of the prepared slides. Statistical Analysi...

Ngày tải lên: 10/08/2014, 10:20