Báo cáo y học: "Three dimensional structure directs T-cell epitope dominance associated with allergy" pptx

... purposes) Clinical and Molecular Allergy Open Access Research Three dimensional structure directs T-cell epitope dominance associated with allergy Scott J Melton* 1 and Samuel J Landry 2 Address: 1 Biomedical ... when analyzed for a population, the dominance of certain epitopes becomes apparent, with some dominant epitopes recognized by a majority of subjects. The CD4+...

Ngày tải lên: 13/08/2014, 13:22

... activity of CBH IB against crystalline cellulose, the enzyme hydrolyses avicel in a processive manner. In processive cellulose hydrolysis, initial hydrolytic attack occurs at the chain end, with ... ., Tuohy, M., Murray, P. & Higgins, T. (2003) Crystallisation and preliminary crystallographic analysis of the catalytic domain cellobiohydrolase IB from Talaromyces emersonii. Acta Crystall...

Ngày tải lên: 23/03/2014, 13:20

... 1.0°C ± 0.2°C compared with 1.7°C ± 0.6°C in joints with active arthri- tis (p < 0.0001). By ROC analysis, an HDI value of 1.3°C yielded a sensitivity of 67% and a specificity of 100%. The area ... frequency, correlated with the Ritchie articular index, grip strength, morning stiffness, erythrocyte sedimentation rate, and pain score [33]. In our study, the HDI performed with greate...

Ngày tải lên: 09/08/2014, 10:22

... vertically in static stance. Examiner error analysis If we denote by Y ijk the observation on participant i (i = 1, , 40) by examiner j (j = 1,2,3) on day k (k = 1,2), then for a first error analysis, ... Eliasziw M, Young SL, Woodbury MG, Fryday-Field K: Statistical methodology for the concurrent assessment of interrater and intrarater reliability. Using goniometric measurements as an exa...

Ngày tải lên: 13/08/2014, 14:20

... Radiofrequency ablation is effective with 96% of primary ablation with few tumoral recurrence and limited morbidity in patients with hepatocellular carcinoma associated with chronic liver disease without ... any review in the RFA therapy literature focused on the efficacy of RFA for HCC associated with CLD without cirrhosis, and cur- rent guide lines on this topic are limited...

Ngày tải lên: 08/08/2014, 17:20

... ultrasonography and cytology. E 2 in serum was measured (approximately 12 hours after tablet intake) by radioimmunoassay (Clinical AssaysTM, DiaSorin, Vercelli, Italy) at baseline and yearly thereafter. BMD ... E 2 after 2 years. The change in TNF-α was also associated weakly with the change in sIL-6R and more strongly with the alterations in IL-1Ra and ESR and inversely to a smaller e...

Ngày tải lên: 09/08/2014, 01:21

... may be inherently associated with increased muscle cross-sectional area due to a larger body size. We have also demonstrated that participation in vigorous physical activity was associated with ... physical activity may, in the setting of vig- orous physical activity, reflect vastus medialis hypertrophy in an attempt to restrain excessive lateral patella displacement. We have previous...

Ngày tải lên: 09/08/2014, 01:22

... restricted to activated T lympho- cytes [5,22,23] and could be observed in resting T lym- phocytes, B lymphocytes, monocytes or granulocytes [20,24]. In contrast, Th2 lymphocytes were reported to produce ... osteoarthritis (OA) were analyzed using Affymetrix HuGeneFL microarrays. Data assessment was done using Affymetrix Microarray Suite 5.0. CXCL, Cys–X–Cys ligand; CXCR, Cys–X–Cys receptor;...

Ngày tải lên: 09/08/2014, 01:23

... mainly associated with infiltrating mononu- clear cells, especially macrophage-like cells surrounding the lesion of lymphocytic infiltration, identified by morphol- ogy and by reactivity with ... interferon-inducible protein 10 associated with Th1 profiles of chemokine receptor in autoimmune pulmonary inflammation of MRL/ lpr mice Fumitaka Shiozawa, Tsuyoshi Kasama, Nobuyuki Yajima,...

Ngày tải lên: 09/08/2014, 01:23

... could very well be so, but when analysing the genes within a QTL it seems reasonable to start with the most likely candidate genes rather than with ran- domly picked ones, especially if the region ... associated with the autoimmune experimental arthritis phenotype, with rat/human gene homology data, and with descriptions of phenotypic gene effects and selected keywords. Each keywo...

Ngày tải lên: 09/08/2014, 06:22