... Central Page 1 of 5 (page number not for citation purposes) Clinical and Molecular Allergy Open Access Review The Hoover's Sign of Pulmonary Disease: Molecular Basis and Clinical Relevance Chambless ... properly cited. Clinical and Molecular Allergy 2008, 6:8 http://www.clinicalmolecularallergy.com/content/6/1/8 Page 3 of 5 (page number not for citation pu...
Ngày tải lên: 13/08/2014, 13:22
... regions. TS28 body body cavity/lining head/neck limb organ system tail body back body blood vessel body bone body connective tissue body muscle body nerve body organ body skin lower body upper ... Dictionary is structured as a directed acyclic graph, and is organized hierarchically both spatially and functionally. The ontology will be used to annotate and integrate diff...
Ngày tải lên: 14/08/2014, 14:21
Báo cáo Y học: The plant S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase is located in both envelope and thylakoid chloroplast membranes pot
... but presumably involved in heme synthesis [4] and POR can associate with the thylakoids [9]. Finally, the ®nal steps of chlorophyll synthesis, such as addition and r eduction of geranylgeranyl chain, ... [10,11] and in cyanobacteria [12] by functional complementation and b y expression of active recombinant protein. In plants, the activity of the S-adenosyl- L -methionine:Mg...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo y học: " The ‘RASor’s’ edge: Ras proteins and matrix destruction in arthritis" pps
... that they appear to ‘spontaneously’ synthesize MMPs. Primary cultures of RA synovial cells contain a mixture of activated fibroblasts, macrophages, and lymphoid cells (T cells, B cells, and neutrophils), ... targets of different signaling pathways [6-8]. Nonetheless, the promo- ters of these MMPs share many common cis-regulatory elements that may respond coordinately [6-8]; the pr...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "The devil’s in the details" pdf
... because they saw it as taking money and attention away from important fundamental research and channeling it into lower-quality, clinically oriented studies that often didn’t go anywhere. ... a year for 10 years (about 1.7% of its current $30 billion budget), but it does not provide any new money to pay for it. So the money must come from somewhere, and the big fear among many...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "Revisiting Lynam’s notion of the “fledgling psychopath": are HIA-CP children truly psychopathic-like" ppsx
... IA-onl y, and CP-only) using measures of psy- chopathic personality, antisocial behavior, and laboratory tasks designed to assess difficulty in delay of gratification and response modulation. Lynam’s ... zation [7]. Psychopathy has a long history of being viewed as consisting of various forms and subty pes. Karpman [60] was first to distinguish between primary and secondary...
Ngày tải lên: 13/08/2014, 18:21
Báo cáo y học: "the emperor’s new shibboleth" pdf
... theory posits that every word in a text has hidden layers of meaning that have been accrued through centuries of historical and cultural processes. The writer is typically unaware of these layers ... that was some- thing of a problem for me, because I thought the theory was a load of crud. This was only partly due to the fact that I couldn’t understand practically anything that De...
Ngày tải lên: 14/08/2014, 14:21
Báo cáo Y học: The reductive hotspot hypothesis of mammalian aging Membrane metabolism magnifies mutant mitochondrial mischief pptx
... stress of superoxide to oxidative stress from hydroxyl and alkoxyl radicals. LDL oxidation may play a key role in atherosclerosis [41]; more generally, however, slightly oxidized LDL is readily imported ... substrate and all of Complex II’s, they would be expected to respond similarly to any long-term intervention. That they do not suggests that much of the NADH produced by the TCA...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains pptx
... from X-ray crystallography, supporting the idea that biosynthesized domain 4 automatically folds into the secondary structure of the native toxin. On the other hand, the spectra of the T2 and T2¢ ... facilities of kinetic analysis by the BIAcore systems. We thank Drs Yoshitaka Nagai and Koichi Suzuki for support and encouragement. We are grateful to Drs Inomata and Hayashi for t...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: The cold-active lipase of Pseudomonas fragi Heterologous expression, biochemical characterization and molecular modeling pdf
... secreted by a signal peptide-independent pathway and calls for further investigation on this subject. Enzyme activity and specificity In the standard tricaprylin hydrolysis assay, rPFL displayed highest ... and biocatalysis under low water conditions [1,2]. Furthermore, fundamental issues concerning the molecular basis of cold activity and the interplay between flexibility and c...
Ngày tải lên: 24/03/2014, 04:21