Báo cáo y học: "House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms" docx

... arterial whole blood. Additionally, a slight increase in red blood cell count, as compared against a normal individual, was observed. Key words: Hb J -Meerut [α 120 (H3) Ala- >Glu (α1)], DNA analysis, ... Hb J- Meerut [α 120 (H3) Ala ->Glu (1)] In A Turkish Male Gunỗag Dinỗol 1 , Serkan Gỹvenỗ 1 , Dedrey Elam 2 , Abdullah Kutlar 2 , Fe...

Ngày tải lên: 02/11/2012, 10:09

... overexpression of the recombinant proteins leading to a compromised mitochondrial integrity rather then to an intrinsic property of the proteins. T his could e xplain the lack of r egulation by free fatty ... protein band d isplaying a molecular weight corresponding to that of the hUCP3. Figure 3 shows the level of hUCP3 expression after infecting L6 cells with increasing...

Ngày tải lên: 21/02/2014, 15:20

... In these authors’ opinions, such studies obviously represent the next logical step in the unfolding story of the modulation of the oligomeric structures of HIV-1 viral enzymes by synthetic peptides ... identification of synthetic peptides and small mole- cules that specifically target the subunit–subunit interfaces of these retroviral enzymes, resu...

Ngày tải lên: 08/03/2014, 09:20

... capacita- tive calcium entry in these cells. These results suggest that stimulation of three isoforms of PLA 2 by thapsigargin liberates free AA that, in turn, induces capacitative calcium in ux in human T-cells. Keywords: ... be activated independently of increases in [Ca 2+ ] i , probably via receptor coupling of this enzyme [36]. Though TG stimu- lated the in...

Ngày tải lên: 08/03/2014, 09:20

... additional data showing that b-expansins resemble ancient and modern cathepsin B, which is a member of the papain (C1) family of cysteine proteinases. Using the Pichia pastoris expression system, ... Properties of group I allergens from grass pollen and their relation to cathepsin B, a member of the C1 family of cysteine prot...

Ngày tải lên: 08/03/2014, 22:20

... Expression of the V-ATPase proteolipid subunit of Acetabularia acetabulum in a VMA3 -deficient strain of Saccharomyces cerevisiae and study of its complementation Mikiko Ikeda 1 , Misato Hinohara 1 , ... was examined using a Saccharomyces cerevisiae VMA3-deficient strain that lacked its own gene for one of the proteolipid subunits of...

Ngày tải lên: 08/03/2014, 23:20

... erosions. Haplotype analysis of the polymorphisms showed no haplotype associations in any of the subgroups. Conclusions We found no evidence of major effects of TLR gene polymorphisms in RA, although ... in the rheumatoid synovium [8], suggesting that innate immunity may be involved in initiating the inflammatory process or in inhibiting regulation mechanisms t...

Ngày tải lên: 09/08/2014, 01:22

... from the Golgi membrane into the cytoplasm. Our working hypothesis is that aberrantly expressed Golgi complex autoantigens may be released into the immune system when cells undergo lysis. By virtue ... prominent function in the processing, transport- ing, and sorting of intracellular proteins subsequent to their synthesis in the rough endoplasmic reticulum. Struc- turall...

Ngày tải lên: 09/08/2014, 01:23

... erosions. Haplotype analysis of the polymorphisms showed no haplotype associations in any of the subgroups. Conclusions We found no evidence of major effects of TLR gene polymorphisms in RA, although ... [8], suggesting that innate immunity may be involved in initiating the inflammatory process or in inhibiting regulation mechanisms that normally prevent chronic in...

Ngày tải lên: 09/08/2014, 13:22

... 7:236 http://www.virologyj.com/content/7/1/236 Page 2 of 6 RESEARC H Open Access Echoviruses are a major cause of aseptic meningitis in infants and young children in Kuwait Ajmal Dalwai, Suhail Ahmad, Widad Al-Nakib * Abstract Background: ... determine the role and type of EVs caus- ing AM cases in Kuwait, an Arabian Gulf country in the Middle East, and...

Ngày tải lên: 12/08/2014, 01:21

... Ren Y, Tang J, Mok MY, Chan AW, Wu A, Lau CS: Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis ... apoptosis and impaired phagocytic clearance of apoptotic cells could play important roles in the break- down of self-tolerance in autoimmune disea...

Ngày tải lên: 12/08/2014, 15:22

... Molecular Allergy Open Access Research House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms Henk ... ng/ml. 0 0 .1 1 10 10 0 Allergen (àg/ml) Interleukin-6 (pg/ml) 0 25 50 75 10 0 12 5 HDM extract Der p1 rDer p5 0 0 .1 1 10 10 0 Al...

Ngày tải lên: 13/08/2014, 13:22

... al., Lack of neo-sensitization to Pen a 1 in patients treated with mite sublingual immunotherapy Clinical and Molecular Allergy 2 010 , 8:4 Received: 4 November 2009 Accepted: 15 March 2 010 Published: ... in which the evaluation of a large number of patients treated with mite sublingual/ oral vaccines did not result in a neo- sensitisation to...

Ngày tải lên: 13/08/2014, 13:22

... Emergency Physicians; Canadian Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases, et al: Surviving Sepsis Campaign: international guidelines for management of severe ... Committee. Statistical analysis Continuous variables were summarized as medians and interquartile ranges. We compared the distribution of continuous variables by using the t test,...

Ngày tải lên: 13/08/2014, 21:21

... Injury 2009, 40(Suppl 4):S2 7-3 5. doi: 10.1186/175 7-7 24 1-1 8-3 4 Cite this article as: Stahel et al., "Metabolic staging" after major trauma - a guide for clinical decision making? Scandinavian ... phases after major trauma. The authors conclude that a better understanding of these pathophys- iological events may provide the treating clinician...

Ngày tải lên: 13/08/2014, 23:20