Báo cáo y học: "Protective effect of the DNA vaccine encoding the major house dust mite allergens on allergic inflammation in the murine model of house dust mite allergy" ppsx

... citation purposes) Clinical and Molecular Allergy Open Access Research Protective effect of the DNA vaccine encoding the major house dust mite allergens on allergic inflammation in the murine model ... detected in the lungs of the control mice (Fig. 2d). In the immunohis- Effect of genetic vaccination on lung histopathology in an anima...

Ngày tải lên: 13/08/2014, 13:22

... greatly reduces the local expression of both these cytokines in the joints of arthritic mice, which may account for the block in joint erosion induced in the CIA model. Addition- ally, VIP shifts the ... RT-PCR of the enzymes involved in the synthesis of these mediators (cyclooxygenase-2 (COX-2) and inducible Figure 1 Cytokine circulating levels in mice at th...

Ngày tải lên: 09/08/2014, 06:23

... exacerbation rates following use of budesonide/ formoterol as maintenance and reliever therapy [10-14] and the efficacy of the combination in the emergency set- ting [34,35]. In conclusion, the budesonide ... beverages in the morning prior to the test days and throughout each of the test days. The study was performed in accordance with the ethical principles th...

Ngày tải lên: 12/08/2014, 11:22

... linear velocity (0.30 ml/min). The theoretical binding capacity of the resins for individual cytokines which was calculated by extrapolation of the increase in cytokine concentration at the column ... simulta- neously at very high concentrations [20]. Although in this study we focused on the cytokine adsorption, one may expect that other proteins can bind to the resin as...

Ngày tải lên: 13/08/2014, 20:21

... combination of ketamine/xylazine in the dose of 20 mg/kg/5 mg/kg (intraperitoneal). Treatment was initiated on the same day of arthritis induction. Drugs The reference drug indomethacine and the ... to inhibit function of phagocytic cells and both monocytic/lymphocytic proinflammatory cytokines involved in rheumatoid synovitis, and this seems to be the key role in t...

Ngày tải lên: 09/08/2014, 10:21

... the Comparison of the frequency of in situ incorporation of digoxigenin (DIG)-dUTP in nuclei of hamster and mouse cells in the absence or presence of TaxFigure 3 Comparison of the frequency of ... intimate interplay between DNAPKcs and Ku explains why an absence of one or the other protein results in increased cytogenetic aberrations in cells. Ku and DNAPKc...

Ngày tải lên: 13/08/2014, 09:21

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Ngày tải lên: 07/08/2014, 18:21

... (Figure 2b). In contrast, STA-5326-treated mice exhibited some inflammatory cell infiltration into the vitreous cavity, but only a few infiltrating cells in the retina with retinal layers remaining intact ... results clearly indicate that oral administration of SAT-5326 is effective in suppress- ing inflammation in EAU. IL-17 production and the proportion of IL-17-producin...

Ngày tải lên: 09/08/2014, 13:22

... inhibition reduced the synovial inflammation, a finding that is well in agreement with those of the present study. Moreover, ASU exhibited an inhibitory effect on iNOS, and therefore on NO production, ... [54]. The present study has limitations largely imposed by the study design. One such limitation is the duration of the study (8 weeks). A longer study would provid...

Ngày tải lên: 09/08/2014, 14:20

... catheter. Amifostine was infused via the Peripheral Dilatation Catheter line intra-aortically and proximally to the occluded segment, 15 min prior to the release of aorta occlusion by deflation of the balloon. ... related to DNA structure and synthe- sis [33]. Indeed, Amifostine induces the DNA- binding activity of wild-type p53, with its most important bio- chemical functi...

Ngày tải lên: 10/08/2014, 10:20