Báo cáo y học: "Impact of IL8 and IL8-Receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections" doc
Báo cáo y học: "Impact of IL8 and IL8-Receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections" doc
... Furthermore, we hypothesized that polymor- phisms within IL8 have opposite effects on the development of asthma and severe RSV infections. The hypothesis was based on the observation that the -251T allele ... infection in the Eng- lish population [9,10]. Thus the first aim of the current study was to test whether our initial hypothesis of an opposite role of...
Ngày tải lên: 13/08/2014, 13:22
Báo cáo y học: "Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy"
... sequence. Conclusions: This study represents that the Gab1 polymorphism was associated with the low risk of H. pylori infection and the high risk of gastric atrophy among seropositive healthy controls, ... affect the H. pylori infection through the level of cytokines which are advantageous to eradication of H. pylori. These results should be interpreted with caution....
Ngày tải lên: 31/10/2012, 15:37
Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx
... role of the D to N mutation; and (c) the role of the sequence and length of the C-terminal extension. To address whether presence of extra residues at the N-terminal of Pfg27 A were responsible ... affected severely by single amino acid mutations. However, in the present study we can exclude this possibility as the D to N mutation is conserved in four of the si...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo y học: "P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis" ppsx
... during the performance of these studies and received 100% of their compensation from the com- pany. Authors' contributions KKB, SAH and EBH performed all of the in vivo studies and analyzed the ... citation purposes) contributes to the development and maintenance of neu- ropathic pain by inducing the synthesis of inflammatory cytokines and other neuroactiv...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: " Secondary infection with Streptococcus suis serotype 7 increases the virulence of highly pathogenic porcine reproductive and respiratory syndrome virus in pigs" potx
... pigs of the coinfected group had symptoms typical of PHFS, such as high fever, anorexia, and red coloration of the ears and the body. The isolation rates of HP-PRRSV and SS7 were higher and the ... effects on the immune system, and allow sec- ondary infection by SS7, thereby further exacerbating the damage to the immune system. In addition, neurotoxicity is...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: " Classic swine fever virus NS2 protein leads to the induction of cell cycle arrest at S-phase and endoplasmic reticulum stress" potx
... up-regulation of GRP78, cyclin A and NF-B suggesting a role of NS2 in ER stress activation. Additionally, NS2 induces cell cycle Figure 3 The analysis of the stages of cell division of expressing ... in the S-phase with a concomitant decrease in the proportion of cells in the G0/G1 ph ase. The cell cycle effects were associated with the activation of NF-B and...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: "Altered immune parameters in chronic alcoholic patients at the onset of infection and of septic shock" pot
... stimulation of cytokine production by lipopolysaccharide, and the alcohol induced decrease in cytokine synthesis was proportional to the level of alcohol con- sumption [6]. Also, levels of production ... the onset of infection (peritonitis/pneumonia), within 12 hours after the onset of septic shock, and 72–96 hours after the onset of sep- tic shock. With each measure...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx
... that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri Jason Doyle 1 , Lyndon E. Llewellyn 1 , Craig S. ... University of Adelaide, South Australia Two neuropeptides have been isolated and identi®ed from the secretions of the skin glands of the Stony Creek Frog Litoria l esueuri...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: " From antibody insult to fibrosis in neonatal lupus – the heart of the matter" pps
... For the 20-week and 22-week CHB hearts, there was a strong positive cor- relation between the absolute number of macrophages and the content of myofibroblasts. The functional implication of the ... a fetus dying in utero at 18 weeks of gestation [23] and the demonstration of patchy lymphoid aggregates through- out the myocardium of an infant delivered at 30 wee...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "α Anti-α-fodrin antibodies do not add much to the diagnosis of Sjögren’s syndrome" pot
... Hoogen FH: The synergistic value of focus score and IgA% score of sublabial salivary gland biopsy for the accuracy of the diagnosis of Sjogren’s syndrome: a 10- year comparison. Rheumatology 2002, ... sera and that the majority of these antibodies are of the IgG and IgA class, but that their frequency in SjS sera is not higher than that of the classic autoantib...
Ngày tải lên: 09/08/2014, 01:23