Báo cáo y học: "Low-dose, long-term macrolide therapy in asthma: An overview" potx

... significantly after 4 weeks of oral macrolide antibiotic administration, suggesting that anti- inflammatory effects may, in part be mediated by the NO pathway [13]. Macrolide antibiotics and asthma therapy Macrolide ... 14-membered ring macrolide antibiot- ics. In an elegant study probing mechanism of action of this effect, Abe et al [4] investigated the effects of clarithro-...

Ngày tải lên: 13/08/2014, 13:22

... [1]. N -acetylcysteine in acetaminophen poisoning and acetaminophen-induced liver failure NAC has been used since the 1970s, and it effectively manages APAP poisoning by glutathione repletion if adminis- tered ... APAP poisoning and APAP-induced liver failure because of the possibility of changed kinetics of NAC in liver injury, reduced efficacy, and adverse hemodynamic changes (vasodilat...

Ngày tải lên: 13/08/2014, 16:20

... measured by FEV 1 and accordingly associated with a higher daytime symptom score and other markers of asthma severity. 45,48 The timing of the infection may also play an important role in the induction ... disturbing airway physiology through a number of different path- ways. Cpn and Mpn species are able to generate proinflammatory cytokines both in vivo and in vitro. 11 Both agents a...

Ngày tải lên: 08/08/2014, 21:20

... assem- bled into a panel providing an average of 13 deletions per chromosome [8]. Using this panel, ESTs can be mapped cytologically and physically to one of 159 deletion ‘bins’ (a bin is a region defined ... particularly true in studies of the fascinating relationship between recombination, synteny and genome evolution and of the regulation of gene expression in polyploid organisms. Re...

Ngày tải lên: 09/08/2014, 20:20

... dehydrogenase (G6PD), hypoxanthine guanine phosphoribosyl transferase (HPRT), phospho- glycerate kinase (PGK1), and a monocarboxylic acid transporter (SLC16A2) show incomplete silencing in ... maintain silencing. An early repressive chromatin mark, tri-methylation of lysine 27 on histone H3 (H3K27me3), is recruited by the Polycomb complex of chromatin-modifying proteins, resulting i...

Ngày tải lên: 09/08/2014, 20:22

... here is an indirect one, it opens the door to examine the X-inactivation status for any polymorphic X-linked gene in normal mice in any tissue. Conclusions Analysis of allele-specific transcript ... 20:1848-1867. 4. Huynh KD, Lee JT: X-chromosome inactivation: a hypothesis linking ontogeny and phylogeny. Nat Rev Genet 2005, 6:410-418. 5. Huynh KD, Lee JT: Imprinted X inactivation in e...

Ngày tải lên: 09/08/2014, 20:22

... the therapy fol- lowing the inj ury, as in cases 11 and 15. Only in cases of lethal wounds can we infer that the injury was grave. In this survey the injuries are arbitrarily categorized according ... 54) since they involve Gods. Out of the remaining 50, only 16 or 32% of injuries involve a Trojan perpetrator, while the majority (34 cases or 68%) involves an Achaean one. In terms...

Ngày tải lên: 10/08/2014, 09:22

... airway obstruction and in modulating the allergic inflammation in asthma. To succeed in finding safe and effective ways of manipulating airway inflammation and airway obstruction by surfactant components ... B lymphocyte differentiation into specific IgE anti- body secreting plasma cells. In addition, interleukin (IL)-5 release by T lymphocytes attracts and activates eosinophils and p...

Ngày tải lên: 12/08/2014, 18:20

... indicating poor agreement. Discussion In this study investigating the reliability of diagnostic coding by physicians trained to collect data in ICU patients, we observed that coding by an external ... pages. Diagnosis coding Coding is performed using the ICD-10 during the ICU stay and immediately at the time of ICU discharge and medical record writing. The treating physician allocates o...

Ngày tải lên: 13/08/2014, 11:22

... negatively charged; orange, hydoxyl; gray, amido; green, proline; purple, cysteine; mid-blue, histidine,; light blue, glycine; olive green, tryptophan and tyrosine; yellow, remaining nonpolar. A. ... charged, red; hydoxyl, orange; amido, grey; proline, green; cysteine, purple; histidine, mid blue; glycine, light blue; tryptophan and tyrosine, olive green; remaining nonpolar, yellowClick here...

Ngày tải lên: 14/08/2014, 14:21