... vaccinating only those aged 50 to 59 results in ICERs of £12,539 and £9,043, vaccinatingonly those aged 60 to 69 results in ICERs of £10,639 and £9,742, and vaccinating all persons aged 65 and ... bene-fits of vaccination, resulting in higher ICERs of £17,807/QALY and £32,809/QALY gained respectively. Anothersensitivity analysis assumed a 10-year duration of fullvaccine efficacy and, in addition, ... administration of the vaccine wereincluded. We assumed that in 50% of cases the vaccinewould be administered by a nurse during a vaccinationappointment and in 50% of cases by a GP during a routinevisit....