Báo cáo y học: "Morphological changes in diabetic kidney are associated with increased O-GlcNAcylation of cytoskeletal proteins including a-actinin " docx

... 13 of 16 RESEARCH Open Access Morphological changes in diabetic kidney are associated with increased O-GlcNAcylation of cytoskeletal proteins including a-actinin 4 Yoshihiro Akimoto 1* , Yuri ... thediabetickidneythemorphological changes in the glomerulus and tubules may be ascribed to the abnormal O-GlcNAcylation of cytoskeletal proteins including...

Ngày tải lên: 13/08/2014, 13:21

... DRB1 In the initial, retrospective study, the frequency of B cells was determined as a percentage of CD19 + lymphocytes from total T lymphocytes and B lymphocytes combined (CD3 + + CD19 + lymphocytes). ... for the induction of collagen-induced arthritis in rodents [34]. Our chief finding of a significant influence of the RA- associated shared epitope on the numbers of circul...

Ngày tải lên: 09/08/2014, 03:24

... known in patients with PAH and SLE [14]. FGR is typically related to placental insufficiency due to reduced blood flow and increased resistance in the uterine arteries. In vitro, the incubation of ... at conception are less likely to experience flares during pregnancy [6]. Our patient had normalized her pulmonary artery pressure assessed by echocardiography just before pregnancy...

Ngày tải lên: 11/08/2014, 17:21

... study showed that increased calories were associated with increased mortality in patients with sepsis and acute respiratory failure [26]. These findings suggest that commonly used rates of energy ... surgery typically display endogenous insulin resistance that is characterized by reduced insulin uptake in peripheral tissues, along with an increase in glucose BG = blood glu...

Ngày tải lên: 13/08/2014, 08:20

... glycogen (Fig. 6a), and with foci of clear hepatocytes (Figs. 6a, 6b). In these clear areas, hepatocytes were slightly bigger and occasionally displayed in two cell-thick plates. In these areas, ... normal proliferative index, the possibility of premalignancy or malignancy should be considered in this type of hypervascular and hyposiderotic nodule, occurring in the context...

Ngày tải lên: 13/08/2014, 13:20

... A: Interleukin-6-type cytokine-induced changes in acute phase protein glycosylation. Annals of the New York Academy of Sciences 1995, 762:319-330. 22. Bond A, Ratkay LG, Waterfield JD, Hay FC: ... gave informed consent. The study is in compliance with the Helsinki Figure 1 MALDI-TOF-MS analysis of tryptic glycopeptides of IgG1 and IgG2MALDI-TOF-MS analysis of tryptic glycope...

Ngày tải lên: 12/08/2014, 11:22

... 671-674 within the NWFDIT epitope. Interestingly, the loss of a putative N-linked glycosylation site in the progressors in the V4 region was compensated for by a gain o f an N- linked glycosylation ... 665 (within the ALDSQWN epitope) resulting in the gain of a tyrosine kinase phosphorylation (TKP) site at codons 665-667, andanNtoSmutationatcodon671resultinginthe gain of a CK2 pho...

Ngày tải lên: 13/08/2014, 01:20

... 50% of CEBPA and HNF4A bind- ing site sequences overlap in the genome, many bind ing events might be non-functional interactions with acces- sible motifs in regions of open chromatin - in yeast, ... for by either one or two point mutations (and not by insertions or deletions), suggesting that changes in TF occupancy are largely caused by the steady accumulation of smal...

Ngày tải lên: 09/08/2014, 20:22

... subjects with SCI. These differences may be due to a complex pathophysiology of SCI in humans which may be additionally complicated by nerve root injury. While pathophysiology of SCI in humans ... injury. Adv Physiol Educ 2002, 26:238-55. 26. Yoshimura N, de Groat WC: Plasticity of Na+ channels in afferent neurones innervating rat urinary bladder following spinal cord injury....

Ngày tải lên: 10/08/2014, 10:20

... assay by down regulation of CFTR expression in the human intestinal cell line T84 in vitro [93]. Ion transport in pyelonephritis In a retrospective study of 300 children with urinary tract infection ... losses, hyponatremia and hypokalemia in diarrhoeal diseases, electrolyte abnormalites in pyelonephritis of early infancy, septicemia induced pulmonary edema, and in hyper...

Ngày tải lên: 11/08/2014, 08:21