... Selective induction of eotaxin release by interleukin-13 or interleukin-4 in humanairway smooth muscle cells is synergistic with interleukin-1β and is mediated by the interleukin-4 receptor α-chain. ... airway inflam-mation, mucus hypersecretion, and airway hyperrespon-siveness (AHR) [1]. In the process of airwayinflammation, various types of cells, such as eosinophils,mast cells, T lymphocytes, ... strongly suggest that in sensi-tized individuals, memory/effector T cells could reach the lung tissue and locally act on the airways, thus woulddirectly induce and maintain basal AHR independently...