... in winter and early spring, and viral infections in the mother during the second and third trimesters of gestation. A strong association between hypofrontality and negative symptoms of schizophrenia, ... symptoms and hypofrontality in both groups, especially in the left superior frontal (Table 5). This relationship between negative symptoms and frontal hypo-perfusion has been supported by many other ... passivity and apathy, difficulty in abstract thinking, lack of spontaneity and flow of conversation, and stereotyped thinking (N1 to N7); and health concerns, anxiety, guilt, tension, mannerisms and...