Báo cáo y học: " Interactions between xenoestrogens and ketoconazole on hepatic CYP1A and CYP3A, in juvenile Atlantic cod (Gadus morhua)" ppsx

... resulted in 70% induction of CYP1A activities and 93% increase in CYP1A protein levels. Ketoconazole and nonylphenol alone or in combination had no effect on CYP3A expression, as analyzed by western ... Access Research Interactions between xenoestrogens and ketoconazole on hepatic CYP1A and CYP3A, in juvenile Atlantic cod (Gadus morhua) Linda...

Ngày tải lên: 13/08/2014, 13:20

... latter observation may indicate an increase in PPII conforma- tion caused by stabilization of the proline-containing peptide upon binding to the SH3-domain [34]. Ligand binding over a concentration range ... arrangement of interaction domains in the regulation of kinase Keywords kinase activity; proline-rich motifs; protein– protein interactions; SH3 domain; tyrosine phosphorylation Corr...

Ngày tải lên: 24/03/2014, 00:21

... on day 0 and day 21. Collagen antibody- induced arthritis was induced by intravenous injection of 2 mg arthrogen mAb cocktail to type II collagen, and 3 days later by intraperitoneal injection ... LPS stimulation or TNBS administration. These results strongly suggest that IL-32 functions in cooperation with other inflam- matory signals in vivo. This induction of these proinflammator...

Ngày tải lên: 09/08/2014, 08:23

... people (a point muta- tion in the Duffy promoter abolishes erythrocyte gene expression). This confers an evolutionary advantage since Duffy-negative erythrocytes are resistant to infection by Plasmodium ... analysis of gene–environment interactions to date is hypothesis driven. The difficulties in quantifying and characterizing environmental risk factors for atopy (including onset an...

Ngày tải lên: 12/08/2014, 18:20

Ngày tải lên: 12/08/2014, 19:22

... Astrocyte cultures, without cytosine arabinoside, were passaged once a week and in 4-6 weeks the neurons were eliminated; the remaining astrocytes were ready for HIV transfection or infection. ... arabinoside) and ready for HIV transfection or infection in two days. Neuronal toxicity assay Neurotoxicity assays were performed by methods described previously [20]. Briefly, human fetal n...

Ngày tải lên: 13/08/2014, 01:20

... mutations in the conserved YPL motif in Nef abolished this binding and eliminated effects of Nef on the proliferation of MVBs and release of viral particles. We conclude that by connecting GagPol and ... in control cells that expressed only GFP. Thus, the proliferation of MVBs requires interactions between Nef and AIP1. Interactions between Nef and AIP1 are required...

Ngày tải lên: 13/08/2014, 09:20

... patterns in estrogen (nonylphenol) and aryl hydrocarbon receptor agonists (PCB-77) interaction using rainbow Trout (Onco- rhynchus mykiss) primary hepatocyte culture. J Toxicol Environ Health A 2006, ... expression. Conclusion The findings in the present study demonstrate the interac- tions between NP and PCB-77 in primary culture of salmon hepatocytes. The AhR-agonist (PCB-77) fu...

Ngày tải lên: 13/08/2014, 13:20

... hydroxyl- amine spin trap 2-ethyl-3-hydroxy-2,4,4 trimethyloxazolidine (OXANOH) by gassing a 10 mM solution of the radical with hydrogen for 45 minutes in the presence of the catalyst platinum ... surgery. Conclusions: The main finding in our study is that MMP-9 in plasma is asscociated with radical production dur- ing carotid endarterectomy, suggesting that this enzyme might be inv...

Ngày tải lên: 26/10/2012, 10:03

... of joint debris that may cause a synovitis. Subchondral bone, periostium, synovium, ligaments, and joint capsule are all richly innervated and contain nerveendingsthatmaybethesourceofpaininOA patients ... [8,15,36], may result in the mani- festation of pain in other joint tissues. This may be a consequence of alterations in joint mechanics resulting in structural changes elsewhere...

Ngày tải lên: 12/08/2014, 15:22