Báo cáo y học: " Early increases in plasminogen activator activity following partial hepatectomy in humans" docx

... that rapid increases in plasminogen activator activity can occur following similarly large liver resection in humans. Thus, increases in plasminogen activator activity are an early event in the remnant ... an increased proliferative activity in the liver remains to be fully established. Presently, the source of the increased uPA activity is uncer- tain. The v...

Ngày tải lên: 13/08/2014, 13:20

... Liver Int 2009, 29:502-510. 3. El-Serag HB, Davila JA, Petersen NJ, McGlynn KA: The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update. Ann Intern ... around 80% [9,10]. Thus, PET may de tect early extrahepatic HCC lesions in clini- cal follow-up. In the reported studies, the PET scan has been successfully used in detecting extrahepati...

Ngày tải lên: 11/08/2014, 00:23

... phenotype induced by thrombin in obesity promotes vascular inflammation and endothelial dysfunction thereby advancing atherosclerosis. Thrombin activates NF-κB thereby up-regulating a variety of cytokines ... the balance in cytokine secretion from non-adipoctyes to adipocytes or this finding may be attributed to the differences in exper- imental design. In the work by Fain et al., the...

Ngày tải lên: 11/08/2014, 08:22

... that the strategy of therapeutic immunointervention may be directed by the type of underlying infection. Key messages • Early statuses of the innate and adaptive immune system in patients with ... cells decrease; in CAP absolute counts of NK cells, CD4-lymphocytes, CD8-lymphocytes and B-lymphocytes decrease; in intraabdominal infections absolute counts of CD8-lym- phocytes and the rat...

Ngày tải lên: 13/08/2014, 20:22

... circulating IFN inducers [2,3]. Type I IFN activity in SLE is associated with disease severity [1]. TNF was the first cytokine convincingly demonstrated to contribute to chronic inflammation in several ... or were slightly decreased in others. The findings appear clinically relevant since patients with an increased IFN response gene activity after anti- TNF therapy had a poor clinic...

Ngày tải lên: 12/08/2014, 11:22

... 0.14*** ActiGraph-min: time spent in moderate-to-vigorous physical activity (2 × minutes spent in vigorous activity + minutes spent in moderate-intensity activity, ActiGraph-count: raw counts in hours with any ... per minute (MET- min) for a day was computed with the following for- mula: 8 × minutes spent in vigorous activity + 4 × min- utes spent in moderate-intensity...

Ngày tải lên: 14/08/2014, 08:20

... particularly FADD and caspase 8, would have been interesting. In summary, the study by Weber and colleagues reaffirms and advances our knowledge of specific pathways involved in lymphocyte apoptosis in ... lacking MyD88 have decreased lymphocyte apoptosis but a significant increase in mortality [14]. MyD88 is an important proximal component of the main pathogen recognition pathways, s...

Ngày tải lên: 13/08/2014, 11:23

... norepinephrine (or increase in its dose) in the whole population (n = 105) Before norepinephrine (introduction/ increase) After norepinephrine (introduction/ increase) Heart rate, beats/min 98 ... contractility and afterload. In the face of the increase in MAP and hence in left ventricular afterload, the increase in CFI induced by norepinephrine suggests that this drug actually in...

Ngày tải lên: 13/08/2014, 21:21

... 37]), p roin¯ammatory c ytokines [30,31] a nd DNA damaging agents [37], whereas the Raf/ERK pathway is preferentially activated upo n binding of growth factors t o receptor tyrosine kinases ([18] ... p38 MAPK/SAPK2 pathway. Independently of these pathways, protein kinase C (PKC) is able to phosphorylate E lk-1 directly. PKC is activated by diacylglycerol, which is formed by phospholipase C (P...

Ngày tải lên: 17/03/2014, 17:20

... Knee instability is very likely to increase inappropriate mechanical loading in many parts of the joint and, in keeping with this, col II and YKL40 expression rose in all locations after ACLT in ... These findings indicate that elevated collagen type II, collagen type I and YKL40 mRNA expression levels are early and sensitive measures of ACLT-induced joint instability independent of...

Ngày tải lên: 09/08/2014, 06:22