Báo cáo y học: " Liver sinusoidal endothelial cell modulation upon resection and shear stress in vitro" doc

... thereby. Background Following partial hepatectomy (PHx) the remaining liver is transfused by normal blood volume, thereby exposing liver sinusoidal endothelial cells (LECs) to excess hemo- dynamic ... forces on the surface of liver sinu- soids and intactness of the endothelial lining. Under normal conditions, liver lobule sinusoids show an intact endothelial lining, consisti...

Ngày tải lên: 13/08/2014, 13:20

... centrifugation, and centrifugal elutriation. This method yields both high purity and functionally intact pig liver sinusoidal cells that can be cultivated in monolayer cultures. Notably, the yield of sinusoidal ... successfully for vital-staining of LSEC either in vivo by intravenous injec- tion, or by administration to LSEC-cultures in vitro. Since FITC-FSA is a highly stable...

Ngày tải lên: 13/08/2014, 13:20

... for determination of cytokines and biomarkers of endothelial dysfunction were stored at - 70°C before laboratory testing. Cytokines and adhesion mole- cules were measured using enzyme-linked immunosorbent assays ... con- tained large numbers of B cells, whereas in coronary artery disease it is typical for lymphocytic infiltrates to consist almost exclusively of T cells [44]. These rep...

Ngày tải lên: 09/08/2014, 06:22

... CD28 and ICOS signaling in T cells and SOCS3 signaling in monocytes resulting in reduced T cell p ro- liferation and cytokine response [112]. Treg cells play an important role in preventing autoimmunity ... CD1d is rapidly up-regulated on cardiac endothelial cells and myocytes and results in infiltr ation of Vg4+ T cells into the myocard ium [93]. As with NKT cells, Vg...

Ngày tải lên: 11/08/2014, 21:21

... addition, cells take up both their own EGF and that secreted by adjoining cells in our model, because cancer cells act in both autocrine and paracrine manner in consuming EGF [40,41]. Each cell encompasses ... overexpressed in many cancers, including non-small cell lung cancer (NSCLC). In silico modeling is considered to be an increasingly promising tool to add useful insigh...

Ngày tải lên: 13/08/2014, 16:21

... pravastatin loaded erythrocytes Hematological Indices To determine the effect of loading process on erythrocytes, normal erythrocytes, erythrocytes sus- pended in PBS, and pravastatin-loaded erythrocytes ... into the erythrocytes should have a degree of water solubility and resistance to degradation within erythrocytes [18]. Certain drugs have been entrapped in erythro- cytes by...

Ngày tải lên: 25/10/2012, 11:10

... general urology outpatient clinic at a Veterans Administration hospital in Brooklyn, NY. It included questions on lower urinary tract symptoms (LUTS) with 0-5 point scale and on quality of life ... frequency and 85% nocturia. The increase in our study is consistent with Irwin et al.’s epidemiologic study. Although a higher prevalence of OAB is ex- pected in our study populat...

Ngày tải lên: 25/10/2012, 11:35

... granulocyte/ macrophage-colony-stimulating factor, GRO-α, and prostaglandin E 2 in various cell types [4,5]. Of these targets, IL-6 and IL-8 are most likely to act as major insti- gators of RA joint inflammation, since ... A, de Haji S, Boonstra J, Gobin S, Daha M, vab Kooten C: Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epith...

Ngày tải lên: 09/08/2014, 01:23

... anti- inflammatory response counteracting tissue injury caused by CNS lupus. Keywords: amyloid precursor protein, β-amyloid protein, cerebrospinal fluid, neuropsychiatric systemic lupus erythematosus, ... tau and MRI-verified brain damage, indicates that Aβ42 might have exerted its toxic- ity locally, leading to sequels. Finally, as previously found in AD [30] and in low-pressure hydr...

Ngày tải lên: 09/08/2014, 01:23

... shown to play major roles in the inflammatory process, anti-inflammatory mediators as well as proinflammatory ones. The cytokine interleukin-10 (IL-10) has been in focus for many years in autoimmune ... respiratory distress; 2, discontinuous inspiratory stridor; 3, continuous inspiratory stridor; 4, con- tinuous inspiratory stridor and abnormal breathing pattern; 5, cyanosis. Mice dev...

Ngày tải lên: 09/08/2014, 01:24