... 1-α-hydroxylation being CYP27B1. A loss of function mutation in CYP2R1 has also been described [34] and deserves further testing. Variants in CYP2R1, CYP27B1 and CYP24A1 or other genes in the metabolic pathway of ... and 25-hydroxyvitamin D3 in the blood and tissues of the 25-hydroxyvitamin D-24-hydroxylase (Cyp24a1) null mouse. Endocrinology 2005, 146:825-834. 32....
Ngày tải lên: 12/08/2014, 16:20
... [11]. They trained a group of intensivists with 2 hours of didactic teaching and 4 hours of practical teaching, and provided a range of pre-recorded examinations for the intensivists to study in their ... the prevention of hospital-acquired infections, the ability of intensivists to perform echocardiography, and the benefit of polymyxin B haemoperfusion in abdo...
Ngày tải lên: 13/08/2014, 18:22
Báo cáo y học: "MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system" docx
... developing and adult zebrafish brainFigure 1 miRNAs expressed in proliferating and/ or differentiating cells in the developing and adult zebrafish brain. In this and other figures, unless otherwise ... in the design of the study and drafting of the manuscript. EB participated in the in situ hybridization and sectioning experiments. FR revised criti- cally...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo y học: "The aryl hydrocarbon receptor-mediated disruption of vitellogenin synthesis in the fish liver: Cross-talk between AHR- and ERα-signalling pathway" ppt
... phosphorus containing protein, and two lipid contain- ing proteins, lipovitellins I and II [5-7]. These become the primary substances stored as yolk. In the female fish, the induction of VTG synthesis ... hepatocytes, showed that the potency of the different classes of the AHR-ligands to inhibit the VTG synthesis was directly related to their capability to induc...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: "Placenta Percreta-Induced Uterine Rupture Diagnosed By Laparoscopy in the First Trimester"
... lower uterine segment; however, in cases of uterine rupture during the first trimester, the site commonly affected is the fundus, as noted in our patient [7]. The uterine ruptures in the first ... evaluated for the differential diagnosis such as appendicitis and hemoperitoneum. The gradual increase in the size of the uterus with advancing pregnancy can caus...
Ngày tải lên: 25/10/2012, 10:56
Báo cáo Y học: Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe pot
... level only after 60 min (Fig. 1). Pyp1p and Pyp2p phosphatases appear to play a key role in the dephosphorylation of the osmotic stress-activated Sty1p [20]. Interestingly, however, the Sty1p activation ... shock induced a quick and transient phosphorylation of Sty1p that became dephosphorylated within 60–90 min. This is likely due to the activity of threonine-phosphatases...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Novel fish hypothalamic neuropeptide Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide pptx
... NPPv in the hypothalamus. The control study using sense RNA probe resulted in a complete absence of the expression of goldfish LPXRFamide peptide mRNA, suggesting the validity of the in situ hybridization technique. ... (PVO) including the NPPv is a source of pituitary afferents in the goldfish [28]. The NLTp is known to be involved in the control of pituit...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Calcium-binding by p26olf, an S100-like protein in the frog olfactory epithelium pot
... constants of the first to fourth binding of Ca 21 by assuming the presence of four steps of sequential and ordered binding. To identify the site of the EF-hand corresponding to the nth binding of Ca 21 , ... K 1 con- centration, 80– 90% of the change in the a helix content was attained by binding of two Ca 21 . Interestingly, in the mutants which have only...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: "Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells" ppsx
... enhancement in the frequency of arthritis in the T cell-deficient mice and the B cell-defi- cient mice suggest that these cells might play regulatory roles in the initiation of disease. Effect of T ... reactivity of the clonally distinct glycopeptide-reactive T cells [7]. To investigate the role of T cells in the acute effector stage of clinical arthritis,...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo y học: "Candida albicans genome sequence: a platform for genomics in the absence of genetics" potx
... are of particular interest to those interested in fungus-host interactions, because many might play roles in the infection process. The genome of the closely related species Candida dubliniensis ... also contains multiple copies of genes involved in the tricarboxylic acid cycle, oligopeptide trans- port and sphingomyelin degradation. These may contribute to the efficie...
Ngày tải lên: 09/08/2014, 20:20