Báo cáo y học: "MHC class I expression protects rat colon ca

Báo cáo y học: "MHC class I expression protects rat colon carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway" ppt

... shown). Conclusions MHC class I expression protects colon carcinoma cells from apoptosis and cytolysis induced by hepatic NK cells, by blocking the perforin/granzyme pathway. This mecha- nism of immune ... Human and murine cytotoxic T lym- phocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cy...

Ngày tải lên : 13/08/2014, 13:20

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Báo cáo y học: "Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients" doc

... between RA disease activity and miRNA expression levels, patients were classified into inac- tive/remission and active patients, based on C-reactive protein (CRP) and erythrocyte sedimentation rate ... addition to RA diagnostics, or monitoring disease progression or treatment efficacy. The underlying mechanisms resulting in increased miRNA expression and inability of miR- 146a t...

Ngày tải lên : 09/08/2014, 13:21

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Báo cáo y học: "Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy" ppsx

... with the y- axis representing the expression ratios between the mutant and wild-type cells and the x-axis the signal intensity in the mutant. The color scale indicates the modulation of hybridization ... were included in the microarray for assessing synthesis variability, and location of the probe within a given open reading frame and of mismatches on hybridi...

Ngày tải lên : 14/08/2014, 20:22

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Báo cáo y học: "Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers" docx

... recently identified cells with characteristics of MPCs in synovial fluid of osteoarthritic patients using FACS analysis and proved their potential to differentiate. Apart from their functionality, there ... in forward/side scatter exhib- ited no difference between isotype and antibody staining. A maximum of 2% positive cells by staining with isotype antibody mouse IG1 or IG2 con...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "Cetuximab in the treatment of metastatic mucoepidermoid carcinoma of the salivary glands: A case report and review of literature" doc

... predictive of sensitivity to the EGFR-tyrosine kinase inhibitor, gefitinib [11]. On the other hand, no activating mutations in the EGFR gene are associated with response to anti-EGFR strategies ... Claudio Pizzocaro - claudio.pizzocaro@spedalicivili.brescia.it; Vittorio D Ferrari - vittoriodf59@excite.it; Giovanni Marini - bscivile@numerica.it * Corresponding author Abstract Introduct...

Ngày tải lên : 11/08/2014, 21:22

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Báo cáo y học: "Early intra-intensive care unit psychological intervention promotes recovery from post traumatic stress disorders, anxiety and depression symptoms in critically ill patients" docx

... clinical psychologists and intensivists from the patients and/ or the patients’ relatives in collaboration with the family physician. Pre-existing psychiatric illness was excluded on the basis of the Diagnostic and ... Italy). Given that, in our experience, clinical psychological activity is usually welcomed by patients and relatives, this study was carried out to verify...

Ngày tải lên : 14/08/2014, 07:21

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Báo cáo y học: "The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus" ppt

... factors, including the longevity of the injected protein and the level of free G-actin in the circulation at sites of inflammation inhibiting the DNase I activity. Our data obtained by a transgenic expression ... E13R:T205K, which enhance activity and impair inhibition by salt, and A114R to eliminate inhibition by G-actin [30-33]. The cDNAs were inserted into the...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: " Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways." ppt

... NF-κB and the p38 MAP kinase signaling pathways in the induction of I Bα expression by LPS. Clinically, NF-κB activation is involved in many chronic disease conditions, such as rheumatoid arthritis, atheroscleorosis, ... intes- tine where the luciferase signal was highly induced. Quan- tification of the luciferase signal showed that inhibition of luciferase activity by bortez...

Ngày tải lên : 11/08/2014, 08:21

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Báo cáo Y học: Molecular cloning, bacterial expression and properties of Rab31 and Rab32 docx

... proteins (RabSF1±SF4). It has been proposed that such sequences may c onvey effector speci®city, whereas the Switch I and II domains primarily convey sensitivity t o the binding of GTP [8]. There ... in Ras (Q61L). This is consistent with evidence that this glutamine residue may participate in GTP h ydrolysis by stabilizing t he catalytic transition state [36]. Moreove r, the Q79L...

Ngày tải lên : 08/03/2014, 16:20

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Báo cáo Y học: The group I-like ribozyme DiGIR1 mediates alternative processing of pre-rRNA transcripts in Didymium iridis pptx

... the ITS1 insert in the correct orientation were linearized by HindIII digestion, while the ITS2 insert was further subcloned into the XbaI/HindIII site of the pBlue- script+ vector (Stratagene) ... [7]. Homing activity of the I- DirI protein has been demonstra- ted by Dir.S956-1 intron mobility studies involving genetic crosses between intron-containing and intron-lacking D...

Ngày tải lên : 23/03/2014, 21:20

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