Báo cáo y học: " Increased proviral load in HTLV-1-infected patients with rheumatoid arthritis or connective tissue disease" potx

... are mainly CD45RO-expressing CD4 + T lymphocytes and the proviral load is reported to correlate with the number of memory T cells [48]. In our HTLV-1-infected cohort with RA or connective tissue ... suggesting that the majority of infiltrated cells were HTLV-1-infected. In the peripheral blood from HTLV-1-infected patients with RA or connective tissue disease...

Ngày tải lên: 13/08/2014, 13:20

... Several factors may explain this increase in CL CR in PT patients. First, urinary creatinine excretion may be involved in such a phenomenon. A higher creatinine urinary excretion was observed in PT compared ... especially for drugs with renal elimination (beta- lactams, ceftazidime, cefepime, piperacillin, vancomycin, aminoglycosides, and so on). Key messages • In ICU patients...

Ngày tải lên: 14/08/2014, 07:21

... psoriasis study analyzed a region previously identified by linkage in sibling pairs, and by thorough haplotype analysis narrowed it down to a single polymorphism (having excluded the remaining ... factor by tumor necrosis factor alpha and interleukin-1 in rheumatoid arthritis. Arthritis Rheum 1998, 41:1258-1265. 39. Lindy O, Konttinen YT, Sorsa T, Ding Y, Santavirta S, Ceponis A, Lo...

Ngày tải lên: 09/08/2014, 01:23

... and microcytotoxicity assays. Preliminary association analysis was conducted by χ 2 test- ing on contingency tables comparing the three genotypic frequencies between cases and control individuals to yield a ... joints involved, with systemic onset disease typically associated with the great- est morbidity. JRA is probably a collection of diseases with complex overlapping etiologies, w...

Ngày tải lên: 09/08/2014, 06:22

... frequently co-occur with anti-Jo-1 antibodies in sera from patients with idiopathic inflammatory myopathy. Clin Exp Immunol 1997, 109:403-405. 41. Yaneva M, Arnett FC: Antibodies against Ku protein in ... Targoff IN: Laboratory testing in the diagnosis and manage- ment of idiopathic inflammatory myopathies. Rheum Dis Clin North Am 2002, 28:859-890. 3. Bohan A, Peter JB: Polymyosi...

Ngày tải lên: 09/08/2014, 10:20

... DeWoody K, Williamson P, Braun J, Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy Study Group: Efficacy and safety of infliximab in patients with ankylosing spondylitis: ... Listing J, Sieper J: Comparison of the Bath Ankylosing Spondylitis Disease Activity Index and the modified version of the index in assessing disease activity in patients with...

Ngày tải lên: 12/08/2014, 12:20

... decline in SGRQ total score (units/year) according to post-bronchodilator FEV 1 RoD quartiles. Abbreviations: SGRQ, St George’s Respiratory Questionnaire; FEV 1 , forced expiratory volume in 1 ... rapid decline in lung function, particularly in the early stages of COPD, would require a study of reproducibility of FEV 1 and its decl ine in individual patients, possibly at short inte...

Ngày tải lên: 12/08/2014, 14:20

... UK) for 40 min at room temperature for fixation and permeabilisation (for iNOS and 4-HNE) or with formalin (for nitrotyrosine and MPO). The endog- enous peroxidase activity was blocked by incubation ... Hospital, Helsinki, Finland, 2 Pulmonary Medicine, Helsinki University Central Hospital, Helsinki, Finland, 3 Clinical Physiology, Helsinki University Central Hospital, Helsinki, Finlan...

Ngày tải lên: 12/08/2014, 16:20

... disease-modifying antirheumatic drug; EIA: enzyme immunoassay; ELISA: enzyme-linked immunosorb- ent assay; MCV: mutated citrullinated vimentin; PTPN22: protein tyrosine phosphatase nonreceptor type 22; ... antibodies could be useful for monitoring the effects of infliximab therapy. Introduction Rheumatoid arthritis (RA) is the most common chronic inflam- matory joint disease, with a wor...

Ngày tải lên: 09/08/2014, 01:22

... tyrosine kinase-2 to the receptor complex (for review [4,5]). Receptor engagement leads to phosphorylation of tyrosine residues in the cytoplasmic domain of gp130. Phosphotyrosine within the YxxQ ... model gained much support from investigators in arthritis research, and so for more than a decade much effort focused on investigating the molecular basis of inflammatory arthritis induce...

Ngày tải lên: 09/08/2014, 01:23