Báo cáo y học: "HIV-1 encoded candidate micro-RNAs and their cellular targets" pot

... no. GSE23044. Briefly, each pair of wild-type and transgenic heart samples were labeled with Hy 3 and Hy5 fluores- cent dyes respectively and hybridized to a miRCURY LNA™ mouse microRNA Array (version ... J Physiol Regul Integr Comp Physiol 2003, 285(3):R552-560. 13. Sayed D, Hong C, Chen IY, Lypowy J, Abdellatif M: MicroRNAs play an essential role in the development of cardiac hypertro...

Ngày tải lên: 10/08/2014, 05:21

... Cas- taneda S, Cornelius LA, Das J, Doweyko AM, et al.: Discovery of N- (2-chloro-6-methyl-phenyl)-2-(6-(4-(2-hydroxyethyl)-piper- azin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxa- mide (BMS-354825), ... may be a candidate predictive and 'surrogate' biomarker. Additionally, EphA2, a target of dasatinib, is a candidate predictor of efficacy in both prostate and breas...

Ngày tải lên: 14/08/2014, 08:20

... cell growth. Transcription of the Scylla and Charybdis genes is induced by hypoxia via the hypoxia-inducible transcription factor HIF. The same induction by HIF and downstream effects on TSC1/TSC2 ... Epalinges, Switzerland), reported that these mutant embryos die at different stages of embryonic development (embryonic day (E) 10.5 for lgs1 -/- lgs2 -/- , and E14.5 for pygo1 -/- pygo2...

Ngày tải lên: 14/08/2014, 14:21

... significantly less medial wall thickening, pulmonary artery hypertension, and right ventricular hypertrophy after 3 weeks at 10% O 2 [17 •• ]. Although the pathophysiology of pulmonary hypertension ... Biophys Acta 2000, 1497:1–10. An excellent review of EC–leukocyte interactions involved in vascular inflam- matory responses to hypoxia. 7. Yan SF, Zou YS, Gao Y, Zhai C, Mackman N, Lee SL,...

Ngày tải lên: 12/08/2014, 18:20

... second MLV type with a distinctly different host range was sub- sequentlyisolatedbyLevyandPincusfromtheNZB mousestrain[2].Thesevirusesweredefinedbytheir apparent inability to infect cells of their ... Glycosylation-dependent inactivation of the ecotropic murine leukemia-virus receptor. J Virol 1994, 68:626-631. 152. Yan Y, Jung YT, Wu T, Kozak CA: Role of receptor polymorphism and glycos...

Ngày tải lên: 13/08/2014, 01:20

... et al. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2011, 19:42 http://www.sjtrem.com/content/19/1/42 Page 2 of 13 and quality standards were synthesized by a pplying the internationally ... reliability (10 articles), and validity (10 articles) of triage scales. One article studied both reliability and validity and was rated differently due to the studied end...

Ngày tải lên: 13/08/2014, 23:20

... these analyses, we investigated which AS events may be coordinated func- tionally and potentially form AS-regulated networks, and which sequence elements in transcripts are likely to play a role ... associations, and gray edges denote pathway-pathway or pathway-CNS function associations. Pathways and CNS functions are in bold letters. Gene names are the NCBI Entrez Gene standard gene...

Ngày tải lên: 14/08/2014, 07:21

... preferentially on one strand (termed directional motifs (DMs)) and thus have sig- nificantly different CF + and CF - values (Figure 3a). Indeed, many motifs are randomly positioned on one strand and ... (N=188) WCATYM (N=128) VCAGT Y (N=212) TCAGTY [DMp2](N=403) Embryo Adult BCACWS (N=149) WTAGTH (N=188) WCATYM (N=128) VCAGT Y (N=212) TCAGTY [DMp2](N=403) N Testis (Parisi, 2004) Ov...

Ngày tải lên: 14/08/2014, 16:21

... co- mutation analysis, we also conclude that Pvt1 and Myc are likely in the same pathway; this may mean that any of the miRNAs directly determine Myc transcript levels by siRNA-type mediated degradation; ... as important as Myc in T lymphomagenesis, and, presumably, in T cell activation. An analysis of the co-mutations in the lymphomas likely place Pvt1 and Myc into the same pathway. Bac...

Ngày tải lên: 13/08/2014, 06:20

... citation purposes) Retrovirology Open Access Short report HIV-1 encoded candidate micro-RNAs and their cellular targets Yamina Bennasser 1 , Shu-Yun Le 2 , ManLungYeung 1 and Kuan-Teh Jeang* 1 Address: ... purposes) Sequences and localization of HIV -encoded miRNA candidatesFigure 1 Sequences and localization of HIV -encoded miRNA candidates. a) Locations for 5 predicted...

Ngày tải lên: 13/08/2014, 13:20