Báo cáo y học: " Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes" doc

... purposes) Retrovirology Open Access Research Human T lymphotropic virus type-1 p30 II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes Bindhu ... Yamasaki Y, Yamada Y, Tomonaga M, Mori- kawa S, Geleziunas R, Yoshimura T, Yamamoto N: Human T- cell leukemia virus type I tax activates transcription of...

Ngày tải lên: 13/08/2014, 13:20

Ngày tải lên: 09/08/2014, 23:20

... turn synergize with the ROS to activate the innate immune sys- tem via TLR-2. Activation of the immune system leads to further production of ROS by activated macrophages, acti- vation of NF-κB and induction ... inhibits KC by up to 83% (p =< 0.0194) (Figure 1A &1B). To demonstrate that the ability of DMSO to inhibit HA-fragment induced cytokine expression was not idiosy...

Ngày tải lên: 11/08/2014, 08:22

... acquiring antioxidant activity toward processes with potential implications in apoptosis [51]. Taken together, these results suggest that APs affect the genes associated with mitochondrial func- tion ... so that it is difficult to interpret which AP class affected those genes. In the human liver tis- sues, typical APs and atypical APs may mediate different functions leading to liver...

Ngày tải lên: 11/08/2014, 17:20

... unaffected control subjects [3]. Based on our results demonstrating that the length of the microsatel- lite is inversely correlated to Fli1 promoter activity and that a shorter microsatellite is ... into Jurkat T cells and assayed for promoter activity. Expression is presented relative to the pGL3 Basic empty vector, which was set to 1. Results are an average of three independen...

Ngày tải lên: 12/08/2014, 15:22

... [1]). Tat binds to a transac- tivation response (TAR) RNA [1] and activates HIV-1 tran- scription by recruiting transcriptional co-activators that include Positive Transcription Elongation Factor ... analyzed the effect of LIS1 on the activity of PP2A in vitro. Our results presented here point to LIS1 as a yet unrecognized regulator of PP2A that may contribute to the regulation of H...

Ngày tải lên: 13/08/2014, 09:20

... cell-arresting method on expression of a cell cycle related gene can be quantitatively estimated from the ratio of two estimated amplitudes in two experiments. The ratio can be used to gauge the variation ... and G2/M may be dif- ferentially affected by thy-thy and thy-noc arrests, respectively. Measurements of the intensities of gene expression from microarray experiments are subje...

Ngày tải lên: 13/08/2014, 23:20

... has different actin-associated cytoskeletal roles. Table 1 Activated metabolic pathways during adipocyte differentiation and their key enzymes (rate limiting steps) Pathway Enzyme/Protein name ... 7 Myoinositol 1-phosphate synthase A1 NP_076116 156 8 Cholesterol biosynthesis/keto-body synthesis 3-hydroxy-3-methylglutaryl-CoA synthase 1 NP_666054 178 4 3-hydroxy-3-methylglutaryl-CoA reductas...

Ngày tải lên: 14/08/2014, 16:20

... K, Lair- more MD: Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes. Retrovirology 2004, 1:39. 26. ... against genotoxic insults to HTLV-1 infected lymphocytes. Conclusion: Collectively, our data are the first to indicate that HTLV-1 p30 expression results in...

Ngày tải lên: 13/08/2014, 05:22

... GCCTTCTTGGCCTTTGCAGCTTTA; H2A Fwd TTCAGTTTCCCGTAGGCCGAGT, H2A Rev GA AGCTTGTTGAGCTCCTCATCGT; H2B Fwd AAGAAGGATGGCAAGAAGCGCAAG; H2B Rev ACTTGGAGCTGGTGTACTTGGTGA; H3 Fwd ATCGCTATCGGCCTGGTACAGT; H3 ... AGCTCAACAAGCTTCTGGGCAA; H2A Rev TTGTGGTGGCTCTCGGTCTTCTT; H2B Fwd TGCGCCCAAGAAGGGTTCTAAA; H2B Rev ACGAAGGAGTTCATGATGCCCA; H3 Fwd TGCTCATCCGCAAACTGCCATT; H3 Rev AGT- GACACGCTTGGCGTGAATA; H4 Fwd ACCG...

Ngày tải lên: 13/08/2014, 06:20