Báo cáo y học: " The retroviral RNA dimer linkage: different structures may reflect different roles" potx

... motif [21], they may contribute to the process of dimerisation and the stability of the resultant dimer [22]. Importantly, it is possible to form heterodimers between transcripts from these viruses ... CAG-tri loops. The differ- ences in these interactions, and when or where they occur, may reflect different demands upon this unique feature, and highlight the elasticity of...

Ngày tải lên: 13/08/2014, 13:20

... comparison of the form of both curves, we also show the CD4 trajectory, standardized to the HIV RNA level ten years after seroconversion (i.e. the values in the CD4 curve are divided by 9.09 on the relative ... viral load, the setpoint theory was introduced soon after the implementation of HIV RNA assays [1,2]. Three components describe the setpoint behaviour after the...

Ngày tải lên: 13/08/2014, 05:22

... involved in RNA trafficking & metabolism Binds pr55 Gag and is in the genomic RNA ribonucleoprotein complex Yes [172, 175] tRNA synthetases Enzyme catalyzing the synthesis of tRNAs for RNA translation Binds ... as the metabolic machineries for RNA in the cytoplasm are made by RNA- binding proteins, some of which mark the RNA before their exit from the nucleus...

Ngày tải lên: 13/08/2014, 09:21

... basis for the importance of gene order in the globin locus is not entirely clear, it is in agreement with the hypothesis that t he genes in the globin locus are competitively regulated by the LCR ... in the absence of HS2, suggesting some f orm of c ommunicatio n between these two elements [52]. The GATA sites are bound by either GATA-1 or GATA-2, the only two members o f the...

Ngày tải lên: 18/03/2014, 01:20

... ATPases, enzymes that become autophosphorylated by the gamma phosphate group of the ATP molecule that they hydrolyze. The Na + / K + -ATPase was the first discovered ion transporter, and indeed the first-discovered ... Interestingly, the electrogenic step in the catalytic cycle of the sodium pump is associated with the E 1 -P conformation of the enzyme. Viewed from this stan...

Ngày tải lên: 24/03/2014, 00:21

... adenovirus-mediated p53 gene therapy and introduction of wild-type p53 into tumor cells represents a potentially valuable tool for the therapy of many types of human cancers [103] mainly by causing cell-cycle arrest ... These pat- terns may ultimately be more predictive than analysis of expression of any single genes. Expression arrays RNA expression patterns may be more functionally...

Ngày tải lên: 12/08/2014, 18:21

... purposes) Retrovirology Open Access Editorial The value of Institute of Human Virology meeting abstracts and beyond Kuan-Teh Jeang* Address: The National Institutes of Health, Bethesda, Maryland, USA Email: ... fact not academics. The users may be patients, students, teachers, or health- care professionals; and they would be barred from infor- mation-access by a fee-based format. Is...

Ngày tải lên: 13/08/2014, 09:21

... purpose or by chance. The respondents may not have understood the question, they may not have been concentrated on the task, or they may have had spe- cial experiences, etc. However, the items ... love/like yourself? 5 BODY20 How much do you like your body? 6 HUG21 How do you like being hugged by your mother? 7 HUG22 How do you like being hugged by your father? 8 FEEL23 How do y...

Ngày tải lên: 13/08/2014, 18:21

... viral RNA behaved differ- ently than predicted by those studying cellular mRNAs. Many of the important discoveries in RNA biology were made by study of viral RNA. The only disadvantage is you have ... is your advice to aspiring scientists who also seek challenging cross disci- plinary work? KB: I have really enjoyed being at the interface of the RNA and retrovirus fields, espec...

Ngày tải lên: 13/08/2014, 05:22

... with components of the RNAi machinery [16] may promote the development of autoimmunity. Conclusion The identification of components of the RNAi machinery as targets of the anti-Su autoantibody system provides ... supported by the identification of a 200 kDa protein associated with the Su antigenic complex as Dicer, the enzyme that converts dsRNA precursors into functional si...

Ngày tải lên: 09/08/2014, 08:22